Vitexin is an
apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a flavone compound that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool.
Apigenin is abundant in parsl ...
flavone
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but substituted derivatives, ...
glucoside
A glucoside is a glycoside that is chemically derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes.
Th ...
, a chemical compound found in the
passion flower
''Passiflora'', known also as the passion flowers or passion vines, is a genus of about 550 species of flowering plants, the type genus of the family Passifloraceae.
''Passiflora'' species are widely cultivated for their striking flowers, fla ...
, ''
Vitex agnus-castus
''Vitex agnus-castus'' (also called vitex, chaste tree / chastetree, chasteberry, Abraham's balm, lilac chastetree, or monk's pepper) is a plant native of the Mediterranean region. It is one of the few temperate-zone species of ''Vitex'', which ...
'' (chaste tree or chasteberry), in the ''
Phyllostachys nigra
''Phyllostachys nigra'', common name, commonly known as black bamboo or purple bamboo ( zh, 紫竹), is a species of bamboo, native plant, native to Hunan, Hunan Province of China, and is widely cultivated elsewhere.
Growing up to tall by broa ...
'' bamboo leaves, in the
pearl millet
Pearl millet (''Cenchrus americanus'', commonly known as the synonym ''Pennisetum glaucum'') is the most widely grown type of millet. It has been grown in Africa and the Indian subcontinent since prehistoric times. The center of diversity, and ...
(Pennisetum millet), and in
Hawthorn.
Metabolism
Goitrogenicity
Goitrogens are substances that disrupt the production of thyroid hormones. This triggers the pituitary to release thyroid-stimulating hormone (TSH), which then promotes the growth of thyroid tissue, eventually leading to goiter.
Goitrogenic dr ...
of millet flavones : Vitexin inhibits
thyroid peroxidase
Thyroid peroxidase, also called thyroperoxidase (TPO), thyroid specific peroxidase or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. Thyroid peroxidase oxidizes iodide ions to form iodine atoms ...
thus contributing to
goiter
A goitre (British English), or goiter (American English), is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly.
Worldwide, over 90% of goitre cases are ca ...
.
*
Vitexin beta-glucosyltransferase
Vitexin is an apigenin flavone glucoside, a chemical compound found in the passion flower, ''Vitex agnus-castus'' (chaste tree or chasteberry), in the ''Phyllostachys nigra'' bamboo leaves, in the pearl millet (Pennisetum millet), and in Hawthor ...
*
Vitexin 2"-O-rhamnoside 7-O-methyltransferase
In enzymology, a vitexin 2"-O-rhamnoside 7-O-methyltransferase () is an enzyme that catalyzes the chemical reaction
:S-adenosyl-L-methionine + vitexin 2"-O-beta-L-rhamnoside \rightleftharpoons S-adenosyl-L-homocysteine + 7-O-methylvitexin 2"-O-bet ...
See also
*
Isovitexin
Isovitexin (homovitexin or saponaretin) is a flavone, namely the apigenin-6-''C''-glucoside. In this case, the prefix 'iso' does not imply an isoflavonoid (the position of the B-ring on the C-ring), but the position of the glucoside on the flavon ...
(or homovitexin, saponaretin) is the apigenin-6-''C''-glucoside.
*
Orientin
Orientin is a flavone, a chemical flavonoid-like compound. It is the 8-C glucoside of luteolin.
Natural occurrences
Orientin is found in '' Adonis vernalis'', in ''Anadenanthera colubrina'' and ''Anadenanthera peregrina'', and in the ''Phyllos ...
, the 3'-OH derivative
References
External links
Vitexin on RDchemicals.com
{{flavone
Flavone glucosides
C-glycoside natural phenols