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''The Andromeda Strain'' is a 1969 techno-thriller novel by
Michael Crichton John Michael Crichton (; October 23, 1942 – November 4, 2008) was an American author and filmmaker. His books have sold over 200 million copies worldwide, and over a dozen have been adapted into films. His literary works heavily feature tech ...
, his first novel under his own name and his sixth novel overall. It is written as a report documenting the efforts of a team of scientists investigating the
outbreak In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire ...
of a deadly extraterrestrial
microorganism A microorganism, or microbe,, ''mikros'', "small") and ''organism'' from the el, ὀργανισμός, ''organismós'', "organism"). It is usually written as a single word but is sometimes hyphenated (''micro-organism''), especially in old ...
in
Arizona Arizona ( ; nv, Hoozdo Hahoodzo ; ood, Alĭ ṣonak ) is a state in the Southwestern United States. It is the 6th largest and the 14th most populous of the 50 states. Its capital and largest city is Phoenix. Arizona is part of the Fou ...
. ''The Andromeda Strain'' appeared in the ''New York Times'' Best Seller list, establishing Michael Crichton as a
genre Genre () is any form or type of communication in any mode (written, spoken, digital, artistic, etc.) with socially-agreed-upon conventions developed over time. In popular usage, it normally describes a category of literature, music, or other f ...
writer.


Plot

A team from an
Air Force An air force – in the broadest sense – is the national military branch that primarily conducts aerial warfare. More specifically, it is the branch of a nation's armed services that is responsible for aerial warfare as distinct from an ...
base is deployed to recover a
military satellite A military satellite is an artificial satellite used for a military purpose. The most common missions are intelligence gathering, navigation and military communications. The first military satellites were photographic reconnaissance missions. ...
that has returned to Earth, but contact is lost abruptly. Aerial surveillance reveals that everyone in Piedmont, Arizona, the town closest to where the satellite landed, is apparently dead. The duty officer of the base tasked with retrieving the satellite suspects it returned with an extraterrestrial
contaminant Contamination is the presence of a constituent, impurity, or some other undesirable element that spoils, corrupts, infects, makes unfit, or makes inferior a material, physical body, natural environment, workplace, etc. Types of contamination Wi ...
and recommends activating "Wildfire", a protocol for a government-sponsored team of scientists intended to contain threats of this nature. The Wildfire team, led by Dr. Jeremy Stone, believes that the satellite—intentionally designed to capture upper-atmosphere
microorganism A microorganism, or microbe,, ''mikros'', "small") and ''organism'' from the el, ὀργανισμός, ''organismós'', "organism"). It is usually written as a single word but is sometimes hyphenated (''micro-organism''), especially in old ...
s for bio-weapon exploitation—returned with a deadly microorganism that kills through nearly instantaneous
blood clotting Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechan ...
. Upon investigating Piedmont, the team discovers the townspeople either died in mid-stride or went "quietly nuts" and committed bizarre suicides. Two survivors—the sick,
Sterno Sterno is a brand of jellied, denatured alcohol sold in a can and meant to be burned directly in its can. Its primary uses are in food service for buffet heating, in the home for fondue, and as a chafing fuel for heating chafing dishes. Other ...
-addicted, geriatric Peter Jackson and the constantly bawling infant Jamie Ritter—are biological opposites who somehow survived the organism. Jackson, Ritter, and the satellite are taken to the secret underground Wildfire laboratory, a secure facility equipped with every known capacity for protection against microorganisms escaping into the environment. Wildfire is hidden in a remote area near Flatrock,
Nevada Nevada ( ; ) is a U.S. state, state in the Western United States, Western region of the United States. It is bordered by Oregon to the northwest, Idaho to the northeast, California to the west, Arizona to the southeast, and Utah to the east. N ...
, sixty miles from
Las Vegas Las Vegas (; Spanish for "The Meadows"), often known simply as Vegas, is the 25th-most populous city in the United States, the most populous city in the state of Nevada, and the county seat of Clark County. The city anchors the Las Veg ...
, concealed in the sub-basements of a legitimate
Department of Agriculture An agriculture ministry (also called an) agriculture department, agriculture board, agriculture council, or agriculture agency, or ministry of rural development) is a ministry charged with agriculture. The ministry is often headed by a minister ...
research station. Dr. Hall is the only scientist authorized to disarm the automatic self-destruct mechanism; he is an unmarried male and thus presumed to make the most dispassionate decisions during crisis. Further investigation determines that the deaths were caused by an extraterrestrial microbe transported by a meteor that crashed into the satellite, knocking it from orbit. The microbe contains chemical elements required for terrestrial life (
hydrogen Hydrogen is the chemical element with the symbol H and atomic number 1. Hydrogen is the lightest element. At standard conditions hydrogen is a gas of diatomic molecules having the formula . It is colorless, odorless, tasteless, non-to ...
and
carbon Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent—its atom making four electrons available to form covalent chemical bonds. It belongs to group 14 of the periodic table. Carbon ma ...
) and appears to have a
crystalline structure In crystallography, crystal structure is a description of the ordered arrangement of atoms, ions or molecules in a crystalline material. Ordered structures occur from the intrinsic nature of the constituent particles to form symmetric patterns ...
, but lacks the DNA, RNA,
proteins Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
, and
amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha ...
s present in all forms of terrestrial life, and directly transforms energy to matter with no discernible byproducts. The microbe, code-named "Andromeda", mutates with each growth cycle, changing its biological properties. The scientists learn that the current form of Andromeda grows only in a narrow pH range; in a too acidic or too
alkali In chemistry, an alkali (; from ar, القلوي, al-qaly, lit=ashes of the saltwort) is a basic, ionic salt of an alkali metal or an alkaline earth metal. An alkali can also be defined as a base that dissolves in water. A solution of a ...
ne growth medium, it will not multiply. Andromeda's ideal pH range is 7.39–7.43, within the range found in normal human blood. Jackson and Ritter survived because both had abnormal blood pH (Jackson acidotic from consumption of Sterno and
aspirin Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat inc ...
, Ritter alkalotic from
hyperventilation Hyperventilation is irregular breathing that occurs when the rate or tidal volume of breathing eliminates more carbon dioxide than the body can produce. This leads to hypocapnia, a reduced concentration of carbon dioxide dissolved in the bloo ...
). However, by the time the scientists realize this, Andromeda has mutated into a form that degrades the lab's plastic seals and escapes
containment Containment was a geopolitical strategic foreign policy pursued by the United States during the Cold War to prevent the spread of communism after the end of World War II. The name was loosely related to the term '' cordon sanitaire'', which ...
. Trapped in a contaminated lab, Dr. Charles Burton demands that Stone inject him with a "universal
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention ...
"; Stone refuses, arguing that it would render Burton too vulnerable to infection by other harmful bacteria. Burton survives because the mutated Andromeda is no longer
pathogen In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a g ...
ic. The mutated Andromeda attacks the
synthetic rubber A synthetic rubber is an artificial elastomer. They are polymers synthesized from petroleum byproducts. About 32-million metric tons of rubbers are produced annually in the United States, and of that amount two thirds are synthetic. Synthetic rubb ...
door and hatch seals within the Wildfire facility, rapidly migrating toward the upper levels and the surface. The self-destruct nuclear weapon is automatically armed when it detects the containment breach, triggering its detonation countdown to prevent the spread of the infection. As the bomb arms, the scientists realize that given Andromeda's ability to generate matter directly from energy, the organism would be able to consume the released energy and ultimately benefit from a nuclear explosion, forming a large indestructible
biofilm A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular po ...
within a day. To halt the detonation, Hall must insert a special key he carries into an emergency substation, one of which should be accessible from any location in Wildfire. Unfortunately, he is trapped in a section that, due to an oversight, has no substation. He must navigate Wildfire's obstacle course of automatic defenses to reach a working substation on an upper level. He barely disarms the bomb before all the air is evacuated from the deepest level of the Wildfire complex, which contains the remainder of the team and their assistants. Andromeda is suspected to have eventually mutated into a benign form and migrated to the upper atmosphere, where the
oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements ...
content is lower, better suiting its growth. The novel's epilogue reveals that a crewed spacecraft, ''Andros V'', was incinerated during atmospheric re-entry, presumably because Andromeda had eaten its tungsten/plastic laminate heat shield and caused it to burn up.


Main characters

* Dr. Jeremy Stone: Professor and chair of the
bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...
department at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is conside ...
; Stone is fictitiously the winner of the 1961
Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accordi ...
, whereas the actual winner was Georg von Békésy. * Dr. Charles Burton: Professor of
Pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
at the
Baylor College of Medicine Baylor College of Medicine (BCM) is a medical school and research center in Houston, Texas, within the Texas Medical Center, the world's largest medical center. BCM is composed of four academic components: the School of Medicine, the Graduate S ...
* Dr. Peter Leavitt: Clinical
microbiologist A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of para ...
; suffers from
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrica ...
* Dr. Mark Hall:
Surgeon In modern medicine, a surgeon is a medical professional who performs surgery. Although there are different traditions in different times and places, a modern surgeon usually is also a licensed physician or received the same medical training as ...
* Prof. Christian Kirke: one of the intended five, an
anthropologist An anthropologist is a person engaged in the practice of anthropology. Anthropology is the study of aspects of humans within past and present societies. Social anthropology, cultural anthropology and philosophical anthropology study the norms an ...
from
Yale Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wor ...
, was hospitalized with appendicitis


Background

Crichton was inspired to write the novel after reading '' The IPCRESS File'' by
Len Deighton Leonard Cyril Deighton (; born 18 February 1929) is a British author. His publications have included cookery books, history and military history, but he is best known for his spy novels. After completing his national service in the Royal Air ...
while studying in the UK. Crichton says he was "terrifically impressed" by the book—"a lot of ''Andromeda'' is traceable to ''Ipcress'' in terms of trying to create an imaginary world using recogniseable techniques and real people." He wrote the novel over three years.


Odd-man hypothesis

The "odd-man hypothesis" is a fictional
hypothesis A hypothesis (plural hypotheses) is a proposed explanation for a phenomenon. For a hypothesis to be a scientific hypothesis, the scientific method requires that one can test it. Scientists generally base scientific hypotheses on previous obse ...
that states that unmarried men are better able to execute the best, most dispassionate decisions in crises—in this case, to disarm the nuclear weapon intended to prevent the escape of organisms from the laboratory in the event the auto-destruct sequence is initiated. In the novel, the odd-man explanation is a page in a
RAND Corporation The RAND Corporation (from the phrase "research and development") is an American nonprofit global policy think tank created in 1948 by Douglas Aircraft Company to offer research and analysis to the United States Armed Forces. It is finance ...
report of the results of test series wherein different people were to make
command decisions ''Command Decisions'' was a series produced by Hoff Productions which aired on The History Channel in 2004. Each episode depicted an historic battle through re-creations, and gave the viewer an opportunity to test his or her skills, strategies, and ...
in nuclear and biological wars and chemical crises. Hall is briefed on the hypothesis after his arrival at Wildfire. In the book, his copy of the briefing materials has the hypothesis pages removed; in the film, he is criticized for failure to read the material beforehand. Dr. Hall is assumed to have the highest "command decision effectiveness index" among the Wildfire team; this is the reason why he is given a control key to the self-destruct mechanism. Hall initially derides this idea, saying that he has no intention of committing suicide before he is told that it is his job to ''disarm'' the weapon, rather than to ''arm'' it: Stone then admits that the odd-man hypothesis, while accurate (in the confines of the book), was essentially a false document used to justify handing over a nuclear weapon to private individuals and out of government control.


Adaptations

In 1971, ''The Andromeda Strain'' was the basis for the film of the same name directed by
Robert Wise Robert Earl Wise (September 10, 1914 – September 14, 2005) was an American film director, producer, and editor. He won the Academy Awards for Best Director and Best Picture for his musical films ''West Side Story'' (1961) and ''The Sound of ...
, and featuring Arthur Hill as Stone, James Olson as Hall,
Kate Reid Daphne Katherine Reid (4 November 1930 – 27 March 1993) was an English-born Canadian stage, film, and television actress. She played more than one thousand roles, most notably onstage in '' Death of a Salesman'', in the 1980 film ''Atlantic C ...
as Leavitt (changed to a female character, Ruth Leavitt), and
David Wayne David Wayne (born Wayne James McMeekan, January 30, 1914 – February 9, 1995) was an American stage and screen actor with a career spanning over 50 years. Early life and career Wayne was born in Traverse City, Michigan, the son of Helen M ...
as Dutton (Burton in the novel). In 2008, ''The Andromeda Strain'' was the basis for an eponymous miniseries executive-produced by Ridley and
Tony Scott Anthony David Leighton Scott (21 June 1944 – 19 August 2012) was an English film director and producer. He was known for directing highly successful action and thriller films such as '' Top Gun'' (1986), '' Beverly Hills Cop II'' (1987), ''D ...
and
Frank Darabont Frank Árpád Darabont (born Ferenc Árpád Darabont, January 28, 1959) is an American film director, screenwriter and producer. He has been nominated for three Academy Awards and a Golden Globe Award. In his early career, he was primarily a ...
, and featuring
Benjamin Bratt Benjamin Bratt (born December 16, 1963) is an American actor and producer who has worked in film and on television. He had supporting roles in the 1990s in such box office hits as ''Demolition Man'' (1993), ''Clear and Present Danger'' (1994), ...
as Stone. Other characters' names and personalities were radically changed from the novel.


Musical adaptations

*
Death metal Death metal is an extreme subgenre of heavy metal music. It typically employs heavily distorted and low-tuned guitars, played with techniques such as palm muting and tremolo picking; deep growling vocals; aggressive, powerful drumming, fe ...
band
Nocturnus Nocturnus, currently Nocturnus AD, is an American death metal band formed in Tampa, Florida, in 1987 by the drummer/vocalist Mike Browning (formerly of Morbid Angel). They were known for their science-fiction themed lyrics and use of keyboards, ...
has a song called "Andromeda Strain" on their début album, '' The Key''. *
Progressive metal Progressive metal (sometimes shortened to prog metal) is a broad fusion music genre melding heavy metal and progressive rock, combining the loud "aggression" and amplified guitar-driven sound of the former with the more experimental, cerebral ...
band Shadow Gallery has a song titled "The Andromeda Strain" about genetically engineered
biological weapons A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism ...
on the album '' Room V''. * Klaus Schulze performed live concert "Andromeda Strain" in 1976 in
Rotterdam Rotterdam ( , , , lit. ''The Dam on the River Rotte (river), Rotte'') is the second largest List of cities in the Netherlands by province, city and List of municipalities of the Netherlands, municipality in the Netherlands. It is in the Prov ...
.


Reception

Reviews for ''The Andromeda Strain'' were overwhelmingly positive, and the novel was an American bestseller, establishing Michael Crichton as a respected novelist and science-fiction writer. *''
The Pittsburgh Press ''The Pittsburgh Press'' (formerly ''The Pittsburg Press'' and originally ''The Evening Penny Press'') was a major afternoon daily newspaper published in Pittsburgh, Pennsylvania, from 1884 to 1992. At one time, the ''Press'' was the second larg ...
'' said it was "Relentlessly suspenseful... A hair-raising experience." *''
Detroit Free Press The ''Detroit Free Press'' is the largest daily newspaper in Detroit, Michigan, US. The Sunday edition is titled the ''Sunday Free Press''. It is sometimes referred to as the Freep (reflected in the paper's web address, www.freep.com). It primar ...
'' called it "Hideously plausible suspense...
hat A hat is a head covering which is worn for various reasons, including protection against weather conditions, ceremonial reasons such as university graduation, religious reasons, safety, or as a fashion accessory. Hats which incorporate mecha ...
will glue you to your chair." *''
Library Journal ''Library Journal'' is an American trade publication for librarians. It was founded in 1876 by Melvil Dewey. It reports news about the library world, emphasizing public libraries, and offers feature articles about aspects of professional pract ...
'' said ''The Andromeda Strain'' was "One of the most important novels of the year (1969)." *''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
s Christopher Lehmann-Haupt said "Tired out by a long day in the country, I was awake way past bedtime. My arms were numb from propping up my head. By turning from side to side, I had driven the cats from their place at the foot of the bed, and they were disgruntled. I was very likely disturbing my wife's sleep. But I was well into Michael Crichton's ''The Andromeda Strain''. And he had me convinced it was all really happening."First Ballantine Books Edition: January 1993 *Most other critics say that ''The Andromeda Strain'' is the novel that created the Techno-thriller genre.


Sequel

A sequel titled '' The Andromeda Evolution'', written by Daniel H. Wilson, was released on November 12, 2019.


Notes


References

*Crichton, Michael (1969). ''The Andromeda Strain''. .


External links

* {{DEFAULTSORT:Andromeda Strain, The 1969 American novels 1969 science fiction novels Alfred A. Knopf books American novels adapted into films American science fiction novels Fictional diseases and disorders Novels about diseases and disorders Novels about extraterrestrial life American novels adapted into television shows Novels by Michael Crichton Novels set in Arizona Science fiction horror novels Science fiction novels adapted into films Techno-thriller novels Yavapai County, Arizona