Tetramethyl bisphenol F (TMBPF) is a new

coating A coating is a covering that is applied to the surface of an object, usually referred to as the substrate. The purpose of applying the coating may be decorative, functional, or both. Coatings may be applied as liquids, gases or solids e.g. Pow ...

intended as a safer replacement for bisphenol A and

bisphenol F Bisphenol F (BPF; 4,4′-dihydroxydiphenylmethane) is an organic compound with the chemical formula . It is structurally related to bisphenol A (BPA), a popular precursor for forming plastics, as both belong to the category of molecules known as b ...

to use in epoxy linings of aluminium cans and

steel can A steel can, tin can, tin (especially in British English, Australian English, Canadian English and South African English), steel packaging, or can is a container for the distribution or storage of goods, made of thin metal. Many cans re ...

s. It was previously suggested as an insulator in electronic circuit boards. Polymerisation of tetramethyl bisphenol F occurs with epichlorohydrin when heated between 40 and 70 °C using an alkali as a catalyst to form the resin used as a coating.

Health and Environmental Effects

Causes serious eye irritation. May cause respiratory and skin irritation. Very toxic to aquatic life.

Human Endocrine Effects

According to tests TMBPF does not have any effect on the endocrine system; it does not leach out of cans because unlike BPA it is fully polymerized when deposited on the metal, so there is no free chemical to leach out. Tetramethyl bisphenol F was tested on rats to see if there were effects like male or female hormones. It had almost no effects like this. However, a different study did find effects.

References

{{Reflist, {{Cite journal , last1=Szafran , first1=Adam T. , last2=Stossi , first2=Fabio , last3=Mancini , first3=Maureen G. , last4=Walker , first4=Cheryl L. , last5=Mancini , first5=Michael A. , date=2017-07-13 , title=Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis , journal=PLOS ONE , volume=12 , issue=7 , pages=e0180141 , doi=10.1371/journal.pone.0180141 , pmc=5509144 , pmid=28704378, bibcode=2017PLoSO..1280141S , doi-access=free Commodity chemicals Coatings Plasticizers