tripartite motif containing 45, also known as TRIM45, is a human

gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...

. This gene encodes a member of the

tripartite motif family The tripartite motif family (TRIM) is a protein family. Function Many TRIM proteins are induced by interferons, which are important component of resistance to pathogens and several TRIM proteins are known to be required for the restriction of infe ...

. The encoded protein may function as a ranscriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.

References

Further reading