TP-003 is an
anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to
benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, ...
drugs, but is structurally distinct and so is classed as a
nonbenzodiazepine anxiolytic. It is a positive allosteric modulator at the benzodiazepine binding site of
GABAA receptors.
It has modest
anticonvulsant
Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of ...
activity although less than that of
diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, ...
.
See also
*
Imidazopyridine
*
L-838,417
References
Tertiary alcohols
Anxiolytics
GABAA receptor positive allosteric modulators
Imidazopyridines
Nitriles
Fluoroarenes
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