Transforming acidic coiled-coil-containing protein 1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''TACC1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
The function of this gene has not yet been determined; however, it is speculated that it may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers.
Interactions
TACC1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization advocating for the legal and human rights of children with intersex traits. The organization was founded in 2006 and fo ...
with:
*
Aurora A kinase
Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the ''AURKA'' gene.
Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during ...
,
*
Aurora B kinase
Aurora kinase B is a protein that functions in the attachment of the mitotic spindle to the centromere and in cytokinesis.
Discovery
In 1998, Aurora kinase B was identified in humans by a polymerase chain reaction screen for kinases that are o ...
,
[
* ]BARD1
BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the ''BARD1'' gene. The human BARD1 protein is 777 amino acids long and contains a RING finger domain (residues 46-90), four ankyrin repeats (residues 420-555), and a ...
,[
* ]SNRPG
Small nuclear ribonucleoprotein G is a protein that in humans is encoded by the ''SNRPG'' gene.
Interactions
SNRPG has been shown to interact with DDX20
Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem- ...
,[
]
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
{{gene-8-stub