Syringetin is an
''O''-methylated flavonol, a type of flavonoid. It is found in
red grape (absent in white grape),
in ''
Lysimachia congestiflora'' and in ''
Vaccinium uliginosum
''Vaccinium uliginosum'' (bog bilberry, bog blueberry, northern bilberry or western blueberry) is a Eurasian and North American flowering plant in the genus ''Vaccinium'' within the heath family.
Distribution
''Vaccinium uliginosum'' is native ...
'' (bog billberries). It is one of the
phenolic compounds present in wine.
It induces human osteoblast differentiation through
bone morphogenetic protein-2/
extracellular signal-regulated kinase
In molecular biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and p ...
1/2 pathway.
Metabolism
Syringetin is formed from
laricitrin by the action of the enzyme laricitrin 5′-''O''-methyltransferase
[ ( myricetin ''O''-methyltransferase).
]
Glycosides
* Syringetin-3-''O''-galactoside[
* Syringetin-3-''O''-glucoside]Larix sibirica
''Larix sibirica'', the Siberian larch or Russian larch, is a frost-hardy tree native to western Russia, from close to the Finnish border east to the Yenisei valley in central Siberia, where it hybridises with the Dahurian larch ''L. gmelinii' ...
''
* Syringetin 3-''O''-(6′′-acetyl)-β-glucopyranoside found in ''Picea abies
''Picea abies'', the Norway spruce or European spruce, is a species of spruce native to Northern, Central and Eastern Europe.
It has branchlets that typically hang downwards, and the largest cones of any spruce, 9–17 cm long. It is very close ...
'' (Norway spruce)
References
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O-methylated flavonols
Resorcinols