Zinc transporter ZIP4 is a
transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the cell membrane. Many transmembrane proteins function as gateways to permit the transport of specific substances across the membrane. They frequent ...
which in humans is encoded by the ''SLC39A4''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
. It is associated with
acrodermatitis enteropathica
Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc through the inner lining of the bowel, the mucous membrane. It is characterized by inflammation of the skin (dermatitis) around bodily openings ...
.
See also
*
Solute carrier family
References
External links
OMIM entry on ACRODERMATITIS ENTEROPATHICA, ZINC-DEFICIENCY TYPE; AEZ
*
Solute carrier family
{{membrane-protein-stub