Protein SET, also known as Protein SET 1, is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''SET''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Interactions
Protein SET has been shown to
interact
Advocates for Informed Choice, doing business as, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex trai ...
with:
*
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Acidic leucine-rich nuclear phosphoprotein 32 family member A is a protein that in humans is encoded by the ''ANP32A'' gene. It is one of the targets of an oncomiR, MIRN21.
Interactions
Acidic leucine-rich nuclear phosphoprotein 32 family member ...
,
* CDK5R1
Cyclin-dependent kinase 5 activator 1 is an enzyme that in humans is encoded by the ''CDK5R1'' gene.
Function
The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is ...
,
* KLF5
Krueppel-like factor 5 is a protein that in humans is encoded by the ''KLF5'' gene.
Function
This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epi ...
,
* NME1
Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the ''NME1'' gene. It is thought to be a metastasis suppressor.
Function
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metasta ...
, and
* TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A is an enzyme that in humans is encoded by the ''TAF1A'' gene.
Function
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TA ...
.
References
Further reading
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Histone Acetyltransferase Inhibitor
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