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Subhash Mukherjee (16 January 1931 – 19 June 1981) was an Indian
scientist A scientist is a person who Scientific method, researches to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engag ...
,
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
who created the world's second and India's first child using in-vitro fertilisation. Kanupriya Agarwal (Durga), who was born in 1978, just 67 days after the first IVF baby in
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
. Afterwards, Dr. Subhash Mukherjee was harassed by the then West Bengal state government and Indian Government and not allowed to share his achievements with the international scientific community. Dejected, he committed
suicide Suicide is the act of intentionally causing one's own death. Risk factors for suicide include mental disorders, physical disorders, and substance abuse. Some suicides are impulsive acts driven by stress (such as from financial or ac ...
on 19 June 1981. His life and death has been the subject of newspaper reviews and inspired the
Hindi Modern Standard Hindi (, ), commonly referred to as Hindi, is the Standard language, standardised variety of the Hindustani language written in the Devanagari script. It is an official language of India, official language of the Government ...
movie '' Ek Doctor Ki Maut'' (Death of a physician), directed by Tapan Sinha.


Early life

He was born to a Bengali
Brahmin Brahmin (; ) is a ''Varna (Hinduism), varna'' (theoretical social classes) within Hindu society. The other three varnas are the ''Kshatriya'' (rulers and warriors), ''Vaishya'' (traders, merchants, and farmers), and ''Shudra'' (labourers). Th ...
family on 16 January 1931 in
Hazaribagh Hazaribagh is a city and a municipal corporation in Hazaribagh district in the Indian state of Jharkhand. It is also the administrative headquarters of Hazaribagh district and divisional headquarters of North Chotanagpur division. It is known ...
, Bihar and Orissa Province (now in
Jharkhand Jharkhand (; ) is a States and union territories of India, state in East India, eastern India. The state shares its border with the states of West Bengal to the east, Chhattisgarh to the west, Uttar Pradesh to the northwest, Bihar to the north ...
), India. He studied BSc (Hons.) in Physiology (1949) from
University of Calcutta The University of Calcutta, informally known as Calcutta University (), is a Public university, public State university (India), state university located in Kolkata, Calcutta (Kolkata), West Bengal, India. It has 151 affiliated undergraduate c ...
. He then studied
MBBS A Bachelor of Medicine, Bachelor of Surgery (; MBBS, also abbreviated as BM BS, MB ChB, MB BCh, or MB BChir) is a medical degree granted by medical schools or universities in countries that adhere to the United Kingdom's higher education tradi ...
(1955) from the Calcutta National Medical College, which was then affiliated with the
University of Calcutta The University of Calcutta, informally known as Calcutta University (), is a Public university, public State university (India), state university located in Kolkata, Calcutta (Kolkata), West Bengal, India. It has 151 affiliated undergraduate c ...
. He later earned a
PhD A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
(1958) from the
Rajabazar Science College The University College of Science, Technology and Agriculture (formerly known as Rajabazar Science College) are two of five main campuses of the University of Calcutta (CU). The college served as the cradle of Indian sciences, where Raman won t ...
campus of
University of Calcutta The University of Calcutta, informally known as Calcutta University (), is a Public university, public State university (India), state university located in Kolkata, Calcutta (Kolkata), West Bengal, India. It has 151 affiliated undergraduate c ...
in 'Reproductive Physiology' under the stewardship of Prof. Sachchidananda Banerjee. Later he earned his second PhD from the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
in 1967 in 'Reproductive Endocrinology'.


Career

After completing his MBBS from Calcutta National Medical College, he worked as a Lecturer, Reader and Professor of Physiology at NRS Medical College, Kolkata from 1967 to 1975. While working with Sunit Mukherji, a Cryobiologist and Gynecologist Dr. Saroj Kanti Bhattacharya, he became the first physician in India (and second in the world, following British physicians
Patrick Steptoe Patrick Christopher Steptoe CBE FRS (9 June 1913 – 21 March 1988) was an English obstetrician and gynaecologist and a pioneer of fertility treatment. Steptoe was responsible with biologist and physiologist Robert Edwards and the nurse and ...
and Robert Edwards) to perform the
in vitro fertilisation In vitro fertilisation (IVF) is a process of fertilisation in which an ovum, egg is combined with spermatozoon, sperm in vitro ("in glass"). The process involves monitoring and stimulating the Ovulation cycle, ovulatory process, then removing ...
resulting in a test tube baby "Durga" (alias Kanupriya Agarwal) on 3 October 1978. He faced hostility from the West Bengal State government and refusal of the
Government of India The Government of India (ISO 15919, ISO: Bhārata Sarakāra, legally the Union Government or Union of India or the Central Government) is the national authority of the Republic of India, located in South Asia, consisting of States and union t ...
to allow him to attend international conferences. The Bengal government had appointed a panel headed by a radiophysicist – with a gynaecologist, a neurophysiologist and a physiologist as members – to examine the claims by Mukerji. The committee members were Dr. Mrinal Kumar Dasgupta, Chairman Radio-Astronomer (Calcutta University), Dhiren Kundu, Nuclear Physicist (Saha Institute), Dr. J C Chatterjee, Gynecologist and Dr. Ajit Maiti, Neurophysiology (Calcutta University). Mukhopadhyay committed suicide in his Calcutta residence on 19 June 1981 after he was humiliated and insulted by the committee. His recognition is attributable to T. C. Anand Kumar who is credited to be the mastermind behind India's second (officially the first) test-tube baby. Kumar came to the conclusion that he was not the first after reviewing Subhash Mukhopadhyay's personal notes. He was ably helped by Sunit Mukherji, who was a one-time colleague of Mukhopadhyay. Kumar was involved in setting up a research institute in
reproductive biology Reproductive biology includes both sexual and asexual reproduction. Reproductive biology includes a wide number of fields: * Reproductive systems * Endocrinology * Sexual development (Puberty) * Sexual maturity * Reproduction * Fertility H ...
in memory of Mukhopadhyay. A film '' Ek Doctor Ki Maut'' directed by Tapan Sinha was made on his life.


Late recognition

According to scientific records dating from before Mukhopadhyay's eventual recognition, ''Harsha vardhan reddy buri'' (born 16 August 1986) was the first human test tube baby of India. The credit for this achievement went to T. C. Anand Kumar, Director of IRR (ICMR). In 1997, Kumar went to Kolkata to participate in a Science Congress. It was there that all the research documents of Mukhopadhyay were handed over to him. After scrutinising and having discussions with Durga's parents, Kumar became certain that it was in fact Mukhopadhyay who was the architect of first human test tube baby in India. This scientist once mentioned him in a journal on A critique of Mukherjee's technique'', 'The brief description given by Mukherjee in his letter dated 19 October 1978 to the Director of Health Services, Government of West Bengal, the reports he gave over the television interviews and reported in the lay press describe how Mukherjee carried out the procedure of ''in vitro'' fertilisation.' On T.C. Anand Kumar's initiative, Mukhopadhyay was mentioned as the architect of the first Indian test tube baby in a document related to the subject of artificial intercourse in ICMR. India's first test tube baby "Durga", whose parental name is Kanupriya Agarwal, works at a multinational company as a marketing executive in Delhi. On her 25th birthday, she publicly revealed her identity for the first time in a ceremony organised in the memory of Mukhopadhyay. She spoke about Mukhopadhyay in front of the media, expressing joy that Mukhopadhyay's achievement had been acknowledged by a reputed international publication, the ''Dictionary of Medical Biography''. The ''Dictionary of Medical Biography'', published by World Foundation, lists names of 1100 medical scientists from 100 countries around the world for their path breaking contributions to the medical science. Dr. Mukhopadhyay's name is one of those names.Infertility of Indian Establishment
''indiananalysis.blogspot.in''. Retrieved 20 August 2013


See also

*'' Ek Doctor Ki Maut''


References


External links

* {{DEFAULTSORT:Mukhopadhyay, Subhash Bengali people Indian gynaecologists Medical doctors from Kolkata 1981 deaths University of Calcutta alumni Alumni of the University of Edinburgh 1931 births People from Hazaribagh 20th-century Indian medical doctors Suicides in India Indian medical researchers 1981 suicides