Steven Laureys (born 24 December 1968 in

Leuven Leuven (, , ), also called Louvain (, , ), is the capital and largest City status in Belgium, city of the Provinces of Belgium, province of Flemish Brabant in the Flemish Region of Belgium. It is located about east of Brussels. The municipalit ...

) is a Belgian

neurologist Neurology (from , "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the brain, the ...

. He is principally known as a clinician and researcher in the field of neurology of consciousness.

Career

Laureys graduated as a

Medical Doctor A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis ...

from the

Vrije Universiteit Brussel The Vrije Universiteit Brussel (Dutch language, Dutch, ; lit. Free University of Brussels; abbreviated VUB) is a Dutch- and English-speaking research university in Brussels, Belgium. It has four campuses: Brussels Humanities, Science and Engine ...

Belgium Belgium, officially the Kingdom of Belgium, is a country in Northwestern Europe. Situated in a coastal lowland region known as the Low Countries, it is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeas ...

, in 1993. While specializing in neurology he entered a research career and obtained his MSc in

Pharmaceutical Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...

Medicine working on

pain Pain is a distressing feeling often caused by intense or damaging Stimulus (physiology), stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sense, sensory and emotional experience associated with, or res ...

and

stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...

using in vivo

microdialysis Microdialysis is a minimally-invasive sampling technique that is used for continuous measurement of free, unbound analyte concentrations in the extracellular fluid of virtually any tissue. Analytes may include endogenous molecules (e.g. neurotra ...

and

diffusion MRI Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences as well as software that generates images from the resulting data that uses the diffusion of water molecules to generate contrast (vision), contrast ...

in the rat (1997). Drawn by

functional neuroimaging Functional neuroimaging is the use of neuroimaging technology to measure an aspect of brain function, often with a view to understanding the relationship between activity in certain brain areas and specific mental functions. It is primarily used a ...

, he moved to the Cyclotron Research Center at the

University of Liège The University of Liège (), or ULiège, is a major public university of the French Community of Belgium founded in 1817 and based in Liège, Wallonia, Belgium. Its official language is French (language), French. History The university was foun ...

, Belgium, where he obtained his PhD studying residual brain function in the

vegetative state A vegetative state (VS) or post-coma unresponsiveness (PCU) is a disorder of consciousness in which patients with severe brain damage are in a state of partial arousal rather than true awareness. After four weeks in a vegetative state, the patie ...

in 2000. He is board-certified in neurology (1998) and in end-of-life and palliative medicine (2004). He currently leads the Coma Science Group at the Cyclotron Research Centre of the

. He is clinical professor of

neurology Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous syst ...

, at the Liège University Hospital and Research Director at the

National Fund for Scientific Research The National Fund for Scientific Research (NFSR) (Dutch: ''Nationaal Fonds voor Wetenschappelijk Onderzoek'' (NFWO), French: ''Fonds National de la Recherche Scientifique'' (FNRS)) was once a government institution in Belgium for supporting scienti ...

. Laureys is chair of the World Federation of Neurology's Coma and Disorders of Consciousness Research Group and of the European Neurological Society's Subcommittee on Coma and Disorders of Consciousness. Since 2009, he is invited professor at the Royal Academy of Belgium.

Research

His team assesses the recovery of neurological

disability Disability is the experience of any condition that makes it more difficult for a person to do certain activities or have equitable access within a given society. Disabilities may be Cognitive disability, cognitive, Developmental disability, d ...

and of neuronal plasticity in severely brain damaged patients with

altered states of consciousness An altered state of consciousness (ASC), also called an altered state of mind, altered mental status (AMS) or mind alteration, is any condition which is significantly different from a normal waking state. It describes induced changes in one's me ...

by means of multimodal

. It aims at characterizing the brain structure and the residual cerebral function in patients who survive a severe

brain injury Brain injury (BI) is the destruction or degeneration of brain cells. Brain injuries occur due to a wide range of internal and external factors. In general, brain damage refers to significant, undiscriminating trauma-induced damage. A common ...

: patients in

coma A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to Nociception, respond normally to Pain, painful stimuli, light, or sound, lacks a normal Circadian rhythm, sleep-wake cycle and does not initiate ...

minimally conscious state A minimally conscious state (MCS) is a disorder of consciousness distinct from persistent vegetative state (PVS) and locked-in syndrome. Unlike PVS, patients with MCS have partial preservation of conscious awareness. MCS is a relatively new cate ...

and

locked in syndrome Locked-in syndrome (LIS), also known as pseudocoma, is a condition in which a patient is aware but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles in their body except for vertical eye movements and ...

. The importance of this project is twofold. First, these patients represent a problem in terms of

diagnosis Diagnosis (: diagnoses) is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in a lot of different academic discipline, disciplines, with variations in the use of logic, analytics, and experience, to determine " ...

prognosis Prognosis ( Greek: πρόγνωσις "fore-knowing, foreseeing"; : prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) ...

, treatment and daily management. Second, these patients offer the opportunity to explore human consciousness, which is presently one major conundrum

neurosciences Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, ...

have to solve. Indeed, these patients present a complete, nearly graded, range of conscious states from

unconsciousness Unconsciousness is a state in which a living individual exhibits a complete, or near-complete, inability to maintain an awareness of self and environment or to respond to any human or environmental stimulus. Unconsciousness may occur as the r ...

(

) to full

awareness In philosophy and psychology, awareness is the perception or knowledge of something. The concept is often synonymous with consciousness. However, one can be aware of something without being explicitly conscious of it, such as in the case of bli ...

(

locked-in syndrome Locked-in syndrome (LIS), also known as pseudocoma, is a condition in which a patient is aware but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles in their body except for vertical eye movements and ...

). This research confronts clinical expertise and bedside behavioral evaluation of

with state-of-the-art multimodal imaging combining the information from

positron emission tomography Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, r ...

(PET),

functional magnetic resonance imaging Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...

(fMRI), structural

MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and rad ...

electroencephalography Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignal, bio signals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in ...

(EEG), event related potential (ERP) and

transcranial magnetic stimulation Transcranial magnetic stimulation (TMS) is a noninvasive neurostimulation technique in which a changing magnetic field is used to induce an electric current in a targeted area of the brain through electromagnetic induction. A device called a st ...

(TMS) data.

References

External links

Coma Science Group
(with downloadable papers)
Steven Laureys' page at the University of Liège

Cyclotron Research Centre

Liège University Hospital
{{DEFAULTSORT:Laureys, Steven 1968 births Living people Belgian neuroscientists Belgian consciousness researchers and theorists Cognitive neuroscientists Materialists Belgian medical writers Belgian science writers Electroencephalographers 21st-century Belgian scientists Academic staff of Université Laval Vrije Universiteit Brussel alumni

Career

Research

See also

References

External links