Soberana Plus, technical name FINLAY-FR-1A, is a COVID-19 candidate vaccine produced by the Finlay Institute, a

Cuban Cuban or Cubans may refer to: Related to Cuba * of or related to Cuba, a country in the Caribbean * Cubans, people from Cuba, or of Cuban descent ** Cuban exile, a person who left Cuba for political reasons, or a descendant thereof * Cuban Americ ...

epidemiological research institute.

Medical uses

It can be used as a third (

booster Booster may refer to: Amusement rides * Booster (Fabbri ride), a pendulum ride * Booster (HUSS ride), an evolution of the Breakdance ride * Booster (KMG ride), a pendulum ride Arts, entertainment, and media Fictional characters * Booster, a cha ...

) dose for

Soberana 02 Soberana 02 or Soberana 2, technical name FINLAY-FR-2, is a COVID-19 vaccine produced by the Finlay Institute, a Cuban epidemiological research institute. The vaccine is known as PastoCovac () in Iran, where it has been developed in collaborati ...

vaccine at eight weeks. It's also studied as an independent single-dose vaccine.

Efficacy

It combined the Soberana 02, the vaccine booster shot shows an efficacy of 91.2%. The final result of a third dose of Soberana Plus increased the efficacy up to 92.4%. Efficacy against severe disease and death is 100% for the heterologous three-dose regimen.

Clinical trials

Booster dose

Soberana Plus has also been studied as a

booster dose A booster dose is an extra administration of a vaccine after an earlier ( primer) dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to prote ...

for

Single dose

Authorizations

On 20 August 2021, Cuba approved Soberana Plus as a booster after two doses of

. On 23 September, Cuba approved Soberana Plus for COVID-19 survivors over 19 years old. On 7 December, the authorization was expanded to include COVID-19 survivors from 2 to 18 years old.

References

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