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The Hospital for Sick Children, corporately branded as SickKids, is a major
pediatric Pediatrics (American English) also spelled paediatrics (British English), is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, pediatrics covers many of their youth ...
teaching hospital A teaching hospital or university hospital is a hospital or medical center that provides medical education and training to future and current health professionals. Teaching hospitals are almost always affiliated with one or more universities a ...
located on University Avenue in
Toronto Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a p ...
,
Ontario Ontario is the southernmost Provinces and territories of Canada, province of Canada. Located in Central Canada, Ontario is the Population of Canada by province and territory, country's most populous province. As of the 2021 Canadian census, it ...
, Canada. Affiliated with the
Faculty of Medicine A medical school is a tertiary educational institution, professional school, or forms a part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, ...
of the
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...
, the hospital frequently ranks among the top-three pediatric hospitals in the world by ''
Newsweek ''Newsweek'' is an American weekly news magazine based in New York City. Founded as a weekly print magazine in 1933, it was widely distributed during the 20th century and has had many notable editors-in-chief. It is currently co-owned by Dev P ...
'', peaking in 2021 at the top of the list. The hospital's Peter Gilgan Centre for Research and Learning is the largest pediatric research centre the world by area; a skyscraper that holds . SickKids is credited with a number of inventions, including Pablum, a fortified children's cereal, in 1930. In 1968, the hospital opened North America's first pediatric
intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive care medicine. An inten ...
. In 1989, the hospital discovered the gene responsible for
cystic fibrosis Cystic fibrosis (CF) is a genetic disorder inherited in an autosomal recessive manner that impairs the normal clearance of Sputum, mucus from the lungs, which facilitates the colonization and infection of the lungs by bacteria, notably ''Staphy ...
. The hospital's research is primarily based in the fields of
genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian ...
and
oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's Etymology, etymological origin is the Greek word ὄγ ...
. Several of Canada's first surgeries have been performed at SickKids, including separation of conjoined twins, bone marrow transplant, multi-organ transplant, and in-utero cardiac surgery.


History

During 1875, an eleven-room house was rented for a year by a Toronto women's bible study group, led by Elizabeth McMaster. Opened on March 1, it set up six iron cots and "declared open a hospital 'for the admission and treatment of all sick children.'" The first patient, a scalding victim named Maggie, came in on April 3. In its first year of operation, 44 patients were admitted to the hospital, and 67 others were treated in outpatient clinics. In 1876, the hospital moved to larger facilities. In 1891, it moved from rented premises to a purposely-constructed building at
College A college (Latin: ''collegium'') may be a tertiary educational institution (sometimes awarding degrees), part of a collegiate university, an institution offering vocational education, a further education institution, or a secondary sc ...
and Elizabeth Streets. It would remain there for 60 years. The building, known as the
Victoria Hospital for Sick Children Victoria Hospital for Sick Children is a building in Toronto, Ontario, Canada. The building served as a hospital until 1951 and currently serves as the Toronto regional headquarters of Canadian Blood Services. The building has received a Commend ...
, is now the Toronto area headquarters of Canadian Blood Services. In 1951, the hospital moved to its present University Avenue location. On its grounds once stood the childhood home of the Canadian-born movie star
Mary Pickford Gladys Louise Smith (April 8, 1892 – May 29, 1979), known professionally as Mary Pickford, was a Canadian-American film actress and producer. A Canadian pioneers in early Hollywood, pioneer in the American film industry with a Hollywood care ...
. In 1972, the hospital became equipped with a rooftop helipad (CNW8). From 1980 to 1981, the hospital was the site of a series of baby deaths. In December 2022, the hospital was attacked by the
LockBit LockBit is a cybercriminal group proposing ransomware as a service (RaaS). Software developed by the group (also called ransomware) enables malicious actors who are willing to pay for using it to carry out attacks in two tactics where they not o ...
ransomware Ransomware is a type of malware that Encryption, encrypts the victim's personal data until a ransom is paid. Difficult-to-trace Digital currency, digital currencies such as paysafecard or Bitcoin and other cryptocurrency, cryptocurrencies are com ...
gang, who apologized 13 days later and provided a decryptor to the hospital for free.


Contributions to medicine

The hospital was an early leader in the fields of
food safety Food safety (or food hygiene) is used as a scientific method/discipline describing handling, food processing, preparation, and food storage, storage of food in ways that prevent foodborne illness. The occurrence of two or more cases of a simi ...
and
nutrition Nutrition is the biochemistry, biochemical and physiology, physiological process by which an organism uses food and water to support its life. The intake of these substances provides organisms with nutrients (divided into Macronutrient, macro- ...
. In 1908, a
pasteurization In food processing, pasteurization (American and British English spelling differences#-ise, -ize (-isation, -ization), also pasteurisation) is a process of food preservation in which packaged foods (e.g., milk and fruit juices) are treated wi ...
facility for milk was established at the hospital, the first in Toronto, 30 years before milk pasteurization became mandatory. Researchers at the hospital invented an infant cereal, Pablum. The research that led to the discovery of
insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
took place at the nearby
University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...
and was soon applied in the hospital by Gladys Boyd. Dr.
Frederick Banting Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian pharmacologist, orthopedist, and field surgeon. For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physi ...
, one of the researchers, had served his internship at the hospital and went on to become an attending physician there. In 1963, William Thornton Mustard developed the Mustard surgical procedure to help correct heart problems in blue baby syndrome.''Hospital - About SickKids - History and milestones - Milestones - 1951–1975''
accessed 12 June 2015.
In 1989, a team of researchers at the hospital discovered the gene responsible for
cystic fibrosis Cystic fibrosis (CF) is a genetic disorder inherited in an autosomal recessive manner that impairs the normal clearance of Sputum, mucus from the lungs, which facilitates the colonization and infection of the lungs by bacteria, notably ''Staphy ...
.''Hospital - About SickKids - History and milestones - Milestones - 1976–2000''
accessed 20 June 2015
SickKids is a member of the Biotechnology Innovation Organization (BIO), the world's largest advocacy organization representing the
biotechnology Biotechnology is a multidisciplinary field that involves the integration of natural sciences and Engineering Science, engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists ...
industry.


COVID-19 pandemic

During the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
, SickKids engaged in several campaigns to promote
COVID-19 vaccines A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 ( COVID19). Knowledge about the structure and func ...
. SickKids received $99,680.00 from the
Government of Canada The Government of Canada (), formally His Majesty's Government (), is the body responsible for the federation, federal administration of Canada. The term ''Government of Canada'' refers specifically to the executive, which includes Minister of t ...
for two projects through a grant program titled "Encouraging vaccine confidence in Canada." The grant was jointly administered by the
Natural Sciences and Engineering Research Council The Natural Sciences and Engineering Research Council of Canada (NSERC; , CRSNG) is the major federal agency responsible for funding natural sciences and engineering research in Canada. NSERC directly funds university professors and students as ...
(NSERC), the
Social Sciences and Humanities Research Council The Social Sciences and Humanities Research Council of Canada (SSHRC; , CRSH), often colloquially pronounced 'shirk' (), is a Canadian federal research-funding agency that promotes and supports post-secondary research and training in the humani ...
(SSHRC), and the
Canadian Institutes of Health Research The Canadian Institutes of Health Research (CIHR; ; IRSC) is a federal agency responsible for funding health and medical research in Canada. Comprising 13 institutes, it is the successor to the Medical Research Council of Canada. CIHR supports ...
(CIHR). One of the funded proposals was titled “Building COVID-19 Vaccine Confidence: Educating the Educators.” The result was a promotional video titled “COVID-19 Vaccination Information for Education & Child Care Sector Staff” narrated by Dr. Danielle Martin. It was produced by 19 to Zero, and distributed by the
Ontario Ministry of Education The Ministry of Education () is the ministry of the Government of Ontario responsible for government policy, funding, curriculum planning and direction in all levels of public education, including elementary and secondary schools. The ministry ...
to school boards, private schools and child care centres to use in COVID-19 vaccination educational programs. A second proposal was titled “Stop COVID in Kids - School based vaccine education outreach to build trust and empower families”, which received additional funding in the form of a $440,000 grant from the
Public Health Agency of Canada The Public Health Agency of Canada (PHAC; ) is an agency of the Government of Canada that is responsible for public health, emergency preparedness and response, and infectious and chronic disease control and prevention. History The PHAC was f ...
's Immunization Partnership Fund.


Alleged baby murders

In 1980-81, up to 29 baby deaths at SickKids were suspected to have been deliberately murdered by a nurse using the heart medication
digoxin Digoxin (better known as digitalis), sold under the brand name Lanoxin among others, is a medication used to treat various heart disease, heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. ...
. However, after years of inquiry it remains unclear if any murders actually took place or if toxicological tests were misinterpreted. In 2024, retired SickKids paediatric intensive care specialist Dr. Desmond Bohn, who took the latter position, pointed to similarities in the British
Lucy Letby Lucy Letby (born 4 January 1990) is a British former neonatal nurse who was convicted of the murders of seven infants and the attempted murders of seven others between June 2015 and June 2016. Letby came under investigation following a high ...
case.


Unqualified forensic testing

The hospital housed the Motherisk Drug Testing Laboratory. At the request of various child protection agencies, 16,000 hair samples were tested from 2005 to 2015. The former Ontario Appeal Court judge Susan Lang reviewed Motherisk Drug Testing Laboratory and determined that it was not qualified to do forensic testing. Lang also stated, "That SickKids failed to exercise meaningful oversight over MDTL's work must be considered in the context of the hospital's experience with Dr. Charles Smith." The 2008 Goudge Report found also that Dr. Charles Smith, whose forensic testimony led to wrongful convictions in the deaths of children, was not qualified to do forensic testing.


Future

The hospital is in its initial stages of expansion. In 2017, it established the "SickKids VS Limits" fundraising campaign, which continued until 2022 to raise $1.5 billion for the expansion project. The funds will be used to build a patient care centre on University Avenue and a support centre on Elizabeth Street, to renovate the atrium, and to fund pediatric health research. To provide the required area for the buildings, demolition of existing structures was required. That included the removal of a
skyway A skyway, skybridge, skywalk, or sky walkway is an elevated type of pedway connecting two or more buildings in an urban area, or connecting elevated points within mountainous recreational zones. Urban skyways very often take the form of Cover ...
spanning Elizabeth Street, the demolition of the Elizabeth McMaster Building at the northeast corner of Elizabeth Street and Elm Street, and the demolition of the laboratory and administrative building. Construction of the 22-storey Patient Support Centre administrative building occurred on the site of the Elizabeth McMaster Building. Groundbreaking took place in October 2019, topping out took place in September 2022, and it opened in September 2023. The Peter Gilgan Family Patient Care Tower is expected to open in 2029, and the atrium's renovation is expected to be completed by 2031.


Notable patients

* Peter Czerwinski (born 1985), competitive eater known as "Furious Pete"; admitted as a teen while battling anorexia * Mel Hague (1943-2023), author and country singer; admitted at 9 for infantile paralysis (now known as
cerebral palsy Cerebral palsy (CP) is a group of movement disorders that appear in early childhood. Signs and symptoms vary among people and over time, but include poor coordination, spasticity, stiff muscles, Paresis, weak muscles, and tremors. There may b ...
) * Morgan Holmes, sociologist; had a clitorectomy at 7 * Peter G. Kavanagh (1953-2016), radio and television producer; was treated for paralytic poliomyelitis in infancy and childhood * Aqsa Parvez (1991-2007), murder victim; died at the hospital * Leonard Thompson (1908-1935), the first diabetic patient to be treated with insulin; received treatment as a teen * Peter Woodcock (1939-2010), serial killer; was treated extensively throughout his childhood * Molly Burke (born 1994), Canadian YouTuber, Burke was diagnosed at age four with
retinitis pigmentosa Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visua ...
, a condition which causes loss of vision.


Notable staff

*
Benjamin Alman Benjamin Aaron Alman is an American orthopaedic clinician-scientist and currently Chair of Orthopaedic Surgery at Duke University School of Medicine (Durham, North Carolina). Alman is the Distinguished James R. Urbaniak, MD, Professor of Orthop ...
, professor and head of the division of orthopedic surgery, senior scientist in developmental and stem cell biology *
Jean Augustine Jean Augustine (born September 9, 1937) is a Grenada-born Canadian politician. She was the first Black Canadian woman to serve as a federal Minister of the Crown and Member of Parliament. Prior to entering politics in 1993, Jean Augustine h ...
(born 1937), member of the Board of Trustees * Harry Bain (1921-2001), paediatrician (1951-85) *
Frederick Banting Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian pharmacologist, orthopedist, and field surgeon. For his co-discovery of insulin and its therapeutic potential, Banting was awarded the Nobel Prize in Physi ...
(1891-1941), resident surgeon * Sonia Baxendale, member of the Board of Trustees * Jalynn Bennett (1943-2015), member of the Board of Directors * Zulfiqar Bhutta, co-director of the centre for global child health * Gladys Boyd (1894-1969), paediatrician, head of endocrine services * Susan Bradley (born 1940), head of the division of child psychiatry and psychiatrist-in-chief * Manuel Buchwald (born 1940), staff geneticist, scientist, senior scientist, and director of the research institute * Kevin Chan, emergency physician * Jim Coutts (1938-2013), member of the board and foundation * A. Jamie Cuticchia (born 1966), director of bioinformatics * Arlington Franklin Dungy (????-2016), chief of paedodontics * John Taylor Fotheringham (1860-1940), staff member * Julie Forman-Kay, scientist * Vicky Forster, postdoctoral researcher * Anna Goldenberg, senior scientist * William A. Goldie (1873-1950), chief of the infection division * Camilla Gryski, therapeutic clown * Mary Jo Haddad, president and CEO for ten years * Mark Henkelman, senior scientist emeritus * Lisa Houghton, worked at the hospital * Sanford Jackson, research biochemist and biochemist-in-chief * Monica Justice, program head of genetics and genome biology * Lewis E. Kay (born 1961), senior scientist in molecular medicine * Shaf Keshavjee, became a director of the Toronto lung transplant program in 1997 and later a scientist in 2012 * Gideon Koren (born 1947), doctor * Arlette Lefebvre (born 1947), child psychiatrist * Kellie Leitch (born 1970), orthopaedic pediatric surgeon * James MacCallum (1860-1943), ophthalmologist *
Sabi Marwah Sarabjit (Sabi) Singh Marwah (born July 12, 1951) is a former member of the Canadian Senate. He is a former vice chairman and chief operating officer of Scotiabank, retiring in 2014 after 35 years with the bank where he began his career as a fina ...
(born 1951), board member * Michael McCain (born 1958), member of the Board of Trustees * Kathryn McGarry, critical care nurse *
Pleasantine Mill Pleasantine Mill is a cell biologist and group leader at the MRC Human Genetics Unit at the University of Edinburgh. She won the 2018 British Society for Cell Biology Women in Cell Biology Early Career Medal. Early life and education Mill comp ...
, cell biologist who worked at the hospital * Freda Miller, developmental neurobiologist * Caroline Mulroney (born 1974), board member * Edward G. Murphy (1921-2020), senior staff member * Susan Nelles (born c. 1956), nurse accused in 1980-81 baby deaths * Aideen Nicholson (1927-2019), social worker * Isaac Odame, staff physician * Edmund Boyd Osler (1845-1924), trustee * Blake Papsin (born 1959), otolaryngologist * Rulan S. Parekh, former senior scientist in child health evaluative sciences and associate chief of clinical research * Tom Pashby, former senior staff ophthalmologist and sport safety advocate; * Debra Pepler, senior associate scientist * Audrius V. Plioplys, chief resident of child neurology * John Russell Reynolds (1828-1896), assistant physician * Lisa Robinson, former head of the division of nephrology * Edward S. Rogers III (born 1969), director * Johanna Rommens, senior scientist emeritus * Miriam Rossi (1937-2018), pediatrician in the division of adolescent medicine * James Rutka (born 1956), subspecializes in pediatric neurosurgery * Robert B. Salter (1924-2010), surgeon * Bibudhendra Sarkar (born 1935), head of the Division of Biochemistry Research from 1990-2002 * Harry Schachter (born 1933), head of the division of biochemistry research * Chandrakant Shah (born 1936), honorary staff * Louis Siminovitch (1920-2021), helped establish the department of genetics and became geneticist-in-chief * Sheila Singh, neurosurgeon * Charles R. Smith, head forensic pathologist * Valerie Speirs, professor * Ambrose Thomas Stanton (1875-1938), house surgeon * Martin J. Steinbach (1941-2017), senior scientist in department of ophthalmology * Anna Taddio (born 1967), adjunct senior scientist and clinical pharmacist * Kathleen P. Taylor (born 1957), member of the Board of Trustees * Ahmad Teebi (1949-2010), clinical geneticist * John M. Thompson (born 1949), vice chairman of the Board of Trustees * Margaret W. Thompson (1920-2014), genetics researcher * Richard M. Thomson (born 1933), member on the Board of Directors * James Thorburn (1830-1905), physician of the boys' home * Frederick Tisdall (1893-1949), pediatrician * James Marshall Tory (1930-2013), chairman of the board *
Lap-Chee Tsui Lap-Chee Tsui (; born 21 December 1950) is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong. Personal life He grew up in Kowloon, Hong Kong and attended . He studied Biolog ...
(born 1950), member of department of genetics * Norma Ford Walker (1893-1968), first director of the department of genetics * Prem Watsa (born 1950), member of the Board of Trustees * Bryan R.G. Williams, held various positions at the hospital * Ronald Worton (born 1942), director of the diagnostic cytogenetics laboratory * Stanley Zlotkin, clinical nutritionist


References

* * *


Footnotes


External links


The Hospital for Sick Children website

SickKids Foundation website
{{DEFAULTSORT:Hospital for Sick Children 1875 establishments in Ontario Certified airports in Ontario Children's hospitals in Ontario Heliports in Ontario Hospital buildings completed in 1891 Hospitals affiliated with the University of Toronto Hospitals established in 1875 Hospitals in Toronto Pediatric trauma centers