Sakuranetin is a flavan-on, the 7-methoxy derivative of naringenin, found in Polymnia fruticosa and rice, where it acts as a

phytoalexin Phytoalexins are antimicrobial substances, some of which are antioxidative as well. They are defined not by their having any particular chemical structure or character, but by the fact that they are defensively synthesized ''de novo'' by plants ...

against spore germination of '' Pyricularia oryzae''. __TOC__

Glycosides

Sakuranin is the 5-O-

glucoside A glucoside is a glycoside that is chemically derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. Th ...

of sakuranetin.

Metabolism

; biosynthesis Naringenin 7-O-methyltransferase uses naringenin to yield sakuranetin, with S-adenosyl-methionine as the methyl donor. ; biodegradation In compounds like 7-methoxylated flavanones like sakuranetin,

demethylation Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule. A common way of demethylation is the replacement of a methyl group by a hydrogen atom, resulting in a net loss of one carbon and two hydrogen at ...

followed by sulfation occur in model organism '' Cunninghamella elegans''.

References

Aromatase inhibitors O-methylated flavanones Phytoalexins {{aromatic-stub