An STR multiplex system is used to identify specific
short tandem repeats (STRs). STR
polymorphism
Polymorphism, polymorphic, polymorph, polymorphous, or polymorphy may refer to:
Computing
* Polymorphism (computer science), the ability in programming to present the same programming interface for differing underlying forms
* Ad hoc polymorphis ...
s are
genetic markers that may be used to identify a
DNA sequence
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. Th ...
.
The
FBI analyses 13 specific STR
loci
Locus (plural loci) is Latin for "place". It may refer to:
Entertainment
* Locus (comics), a Marvel Comics mutant villainess, a member of the Mutant Liberation Front
* ''Locus'' (magazine), science fiction and fantasy magazine
** '' Locus Award ...
for their database. These may be used in many areas of genetics in addition to their forensic uses.
One can think of a STR multiplex system as a collection of specific STRs which are positionally conserved on a target genome. Hence these can be used as markers. A number of different STRs along with their loci in a particular genome can be used for
genotyping.
For example, the STR multiplex system AmpFlSTR Profiler Plus which analyses nine different STRs (3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820) plus
Amelogenin for sex determination is used for human identification purposes.
References
Repetitive DNA sequences
DNA profiling techniques
Forensic equipment
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