SP3 may refer to:
* sp
3 hybrids, a type of
orbital hybridisation
In chemistry, orbital hybridisation (or hybridization) is the concept of mixing atomic orbitals to form new ''hybrid orbitals'' (with different energies, shapes, etc., than the component atomic orbitals) suitable for the pairing of electrons to f ...
*
Sp3 transcription factor, a protein and the gene which encodes it
*
Savoia-Pomilio SP.3, a reconnaissance and bomber aircraft built in Italy
* , an armed motorboat
* 1971 SP3 or
3922 Heather, a main-belt asteroid discovered on September 26, 1971
* 1984 SP3 or
3155 Lee, a main-belt asteroid discovered on September 28, 1984
* SP3,
a model of steam toy made by British manufacturer Mamod
*
Service pack 3, for computer software
*
Socket SP3, a CPU socket for AMD processors
* SP3, a sink in the
Sima Pumacocha, a cave in Peru
*
Surface Pro 3, a 2-in-1 personal computer by Microsoft
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