CD244 (Cluster of Differentiation 244) is a human
protein encoded by the
gene.
It is also known as Natural Killer Cell Receptor 2B4
This gene encodes a cell surface receptor expressed on
natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.
See also
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Cluster of differentiation
References
Further reading
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External links
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Clusters of differentiation
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