The Rosalind Franklin Institute is a physical sciences research centre devoted to developing new technologies for medical research and the life sciences. They are supported by the
Government of the United Kingdom
His Majesty's Government, abbreviated to HM Government or otherwise UK Government, is the central government, central executive authority of the United Kingdom of Great Britain and Northern Ireland. located at the
Harwell Science and Innovation Campus
The Harwell Science and Innovation Campus is a 700-acre science and technology campus in Oxfordshire, England. Over 6,000 people work there in over 240 public and private sector organisations, working across sectors including Space, Clean Energ ...
, Oxfordshire, England. It is named after an English chemist
Rosalind Franklin
Rosalind Elsie Franklin (25 July 192016 April 1958) was a British chemist and X-ray crystallographer. Her work was central to the understanding of the molecular structures of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), viruses, coal ...
, whose discoveries provided the key data for the correct explanation of the helical structure of DNA in 1953. Launched on 6 June 2018,
it was officially opened on 29 September 2021.
The government approval was announced on 23 February 2017 by
Greg Clark
Gregory David Clark (born 28 August 1967) is a British politician who served as Secretary of State for Business, Energy and Industrial Strategy from 2016 to 2019. He also was Secretary of State for Communities and Local Government from 2015 t ...
, Secretary of State for Business, Energy and Industrial Strategy. According to the press release the basis of the name was "in honour of the pioneering British scientist
osalind Franklinwhose use of X-rays to study biological structures played a crucial role in the discovery of DNA's '
double helix
In molecular biology, the term double helix refers to the structure formed by base pair, double-stranded molecules of nucleic acids such as DNA. The double Helix, helical structure of a nucleic acid complex arises as a consequence of its Nuclei ...
' structure by
Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the Nucleic acid doub ...
and
James Watson
James Dewey Watson (born April 6, 1928) is an American molecular biology, molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper in ''Nature (journal), Nature'' proposing the Nucleic acid ...
". The objective was "to develop disruptive new technologies designed to tackle major challenges in health and life sciences, accelerate the discovery of new treatments for chronic diseases affecting millions of people around the world (such as
dementia
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform activities of daily living, everyday activities. This typically invo ...
), and deliver new jobs and long-term growth to the local and UK economies."
The proposal of the institute was led by
Ian Walmsley
Ian Alexander Walmsley is Provost of Imperial College London where he is also Chair of Experimental Physics. He was previously pro-vice-chancellor for research and Hooke Professor of Experimental Physics at the University of Oxford, and a prof ...
, Pro-Vice Chancellor at the University of Oxford, and the project was initiated under the lead of Andrew Livingston, Professor of Chemical Engineering at Imperial College London and
James H Naismith, Professor of Structural Biology at Oxford University. Originally funded with £103 million by the
Engineering and Physical Sciences Research Council
The Engineering and Physical Sciences Research Council (EPSRC) is a British UK Research Councils, Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical scienc ...
. The Franklin has twelve partners - the
Science and Technology Facilities Council
The Science and Technology Facilities Council (STFC) is a United Kingdom government agency that carries out research in science and engineering, and funds UK research in areas including particle physics, nuclear physics, space science and astr ...
(STFC), Diamond Light Source, University of Birmingham, University of Cambridge, University of Edinburgh, Imperial, King's College London, University of Leeds, Manchester, University of Oxford, University of Southampton, and University College London.
In July 2018,
Vivienne Cox was appointed the first Chair, and in June 2019,
Jim Naismith became the first Director. Paul Matthews became the second Director of the Institute in April 2024.
Research
The work at the Rosalind Franklin Institute will develop new instruments, create new ways of working and integrating previously disparate approaches.
The Franklin has five core scientific themes – Artificial Intelligence, Biological Mass Spectrometry, Correlated Imaging, Next Generation Chemistry and Structural Biology – which work as interdisciplinary teams to develop their new technologies.
Building and facilities
The Rosalind Franklin Institute is located in the Harwell Science and Innovation Campus which is also home to the Diamond Light Source synchrotron, Isis Neutron Spallation source, and the Central Laser Facility.
The building was opened by Professor Lynn Gladden, Chief Executive of the Engineering and Physical Sciences Research Council, which funds the Franklin, and delegates from industry and academia, including Nobel Prize winner Richard Henderson.
The £43m building, constructed by UKRI-STFC working with Mace and project managed by AECOM The IBI group were awarded the "Excellence in Architectural Technology, Medium-Mega
2021" for their work on the building.
References
External links
Profile at the Engineering and Physical Sciences Research CouncilInfo at Cambridge University
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Research institutes in Oxfordshire
Buildings and structures in Oxfordshire
Medical research institutes in the United Kingdom