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Rolf Huisgen (; 13 June 1920 – 26 March 2020) was a German chemist. His importance in synthetic organic chemistry extends to the enormous influence he had in post-war chemistry departments in Germany and Austria, due to a large number of his habilitants becoming professors. His major achievement was the development of the 1,3-dipolar cycloaddition reaction, also called the Huisgen cycloaddition.


Life

Huisgen was born in Gerolstein in
Rhineland-Palatinate Rhineland-Palatinate ( , ; ; ; ) is a western state of Germany. It covers and has about 4.05 million residents. It is the ninth largest and sixth most populous of the sixteen states. Mainz is the capital and largest city. Other cities are ...
and studied in Munich under the supervision of Heinrich Otto Wieland. He completed his Ph.D. in 1943 with a thesis about a strychnine
alkaloid Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large varie ...
. He completed his
habilitation Habilitation is the highest university degree, or the procedure by which it is achieved, in Germany, France, Italy, Poland and some other European and non-English-speaking countries. The candidate fulfills a university's set criteria of excelle ...
in 1947, and was appointed professor at the
University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (; ), is a public research university located in the city of Tübingen, Baden-Württemberg, Germany. The University of Tübingen is one of eleven German Excellenc ...
in 1949. He returned to the University of Munich in 1952, succeeding Wieland, and he remained dedicated to research long after attaining
emeritus ''Emeritus/Emerita'' () is an honorary title granted to someone who retires from a position of distinction, most commonly an academic faculty position, but is allowed to continue using the previous title, as in "professor emeritus". In some c ...
status there in 1988. One of his major achievements was the development of the 1,3-dipolar cycloaddition reaction, also known as the Huisgen cycloaddition or Huisgen reaction. The Huisgen reaction is of paramount importance to the synthesis of heterocyclic compounds, such as vitamins,
alkaloid Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large varie ...
s and antibiotics. Huisgen was a member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
from 1960.Dr. Rolf Huisgen
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
He was also a member of the German National Academy of Sciences Leopoldina and an Honorary Fellow of the
Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society and professional association in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the ...
. He was an Honorary Member of the Gesellschaft Deutscher Chemiker and the Chemical Society of Japan. He was awarded the Liebig Medal in 1961, the Lavoisier Medal from the Société Chimique de France in 1965, and the Adolfo Quilico Medal from the Società Chimica Italiana in 1987, among others. He was elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
in 1989. He received several
honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or '' ad hon ...
s, including from the FU Berlin in 2010. Sixteen of his students became professors in Germany alone, including , Johann Gasteiger, Bernd Giese, , Johann Mulzer, Hans-Ulrich Reissig, and Ivar Karl Ugi.Chemistry Tree Rolf Huisgen
Academictree chemistry, retrieved 12 February 2018


Personal life

His daughter, mathematician Birge Huisgen-Zimmermann, was born in 1946. He died in Munich on 26 March 2020, aged 99.


Publications

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References


Literature

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External links

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Rolf Huisgen: ''The Chemical Adventurer''
scripps.edu
Prof. Dr. Rolf Huisgen, em.
Faculty of Chemistry and Pharmacy,
LMU Munich The Ludwig Maximilian University of Munich (simply University of Munich, LMU or LMU Munich; ) is a public university, public research university in Munich, Bavaria, Germany. Originally established as the University of Ingolstadt in 1472 by Duke ...
{{DEFAULTSORT:Huisgen, Rolf 1920 births 2020 deaths People from Gerolstein 20th-century German chemists Ludwig Maximilian University of Munich alumni Academic staff of the Ludwig Maximilian University of Munich Foreign associates of the National Academy of Sciences