Rnd is a subclass of the Rho family of
GTPases
and includes:
*
Rnd1
*
Rnd2
*
Rnd3
Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3.
Like other members of the Rho family of Ras-related GTPases it regula ...
(also called RhoE)
Functions include downregulation of
stress fibre
Stress fibers are contractile actin bundles found in non-muscle cells. They are composed of actin (microfilaments) and non-muscle myosin II (NMMII), and also contain various crosslinking proteins, such as α-actinin, to form a highly regulated ...
s and
focal adhesions.
See also
*
Rho family of GTPases
References
EC 3.6.5
{{3.6-enzyme-stub