Razupenem (PTZ-601) is a broad spectrum injectable
antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
, from the
carbapenem
Carbapenems are a class of very effective antibiotic agents most commonly used for treatment of severe bacterial infections. This class of antibiotics is usually reserved for known or suspected multidrug-resistant (MDR) bacterial infections. Si ...
subgroup of
beta-lactam antibiotics. It was developed as a replacement drug to combat bacteria that had acquired
antibiotic resistance
Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. This resistance affects all classes of microbes, including bacteria (antibiotic resis ...
to commonly used antibiotics. Razupenem performed well against a variety of bacterial strains,
but further development is in doubt due to a high rate of side effects in Phase II clinical trials.
References
{{CephalosporinAntiBiotics
Carbapenem antibiotics