
RNA recognition motif, RNP-1 is a putative
RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydra ...
-binding
domain
Domain may refer to:
Mathematics
*Domain of a function, the set of input values for which the (total) function is defined
** Domain of definition of a partial function
**Natural domain of a partial function
**Domain of holomorphy of a function
*Do ...
of about 90 amino acids that are known to bind single-stranded RNAs. It was found in many
eukaryotic
Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bact ...
proteins.
The largest group of single strand
RNA-binding protein
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells and participate in forming ribonucleoprotein complexes.
RBPs contain various structural motifs, such as RNA recognition moti ...
is the eukaryotic RNA recognition motif (RRM) family that contains an eight amino acid RNP-1 consensus sequence.
RRM proteins have a variety of RNA binding preferences and functions, and include heterogeneous nuclear ribonucleoproteins (
hnRNP Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA). The presence of the p ...
s), proteins implicated in regulation of
alternative splicing (SR,
U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the ''U2AF2'' gene.
Function
In eukaryotes, the introns in the transcribed pre-mRNA first have to be removed by spliceosome in order to form a mature mRNA. A spliceo ...
,
Sxl), protein components of small nuclear ribonucleoproteins (U1 and U2
snRNP
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pr ...
s), and proteins that regulate RNA stability and translation (
PABP, La, Hu).
The RRM in heterodimeric splicing factor
U2 snRNP auxiliary factor appears to have two RRM-like domains with specialised features for protein recognition.
The motif also appears in a few single stranded DNA binding proteins.
The typical RRM consists of four anti-parallel
beta-strand
The beta sheet, (β-sheet) (also β-pleated sheet) is a common motif of the regular protein secondary structure. Beta sheets consist of beta strands (β-strands) connected laterally by at least two or three backbone hydrogen bonds, forming a gen ...
s and two
alpha-helices
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a right hand-helix conformation in which every backbone N−H group hydrogen bonds to the backbone C=O group of the amino acid located four residues earli ...
arranged in a beta-alpha-beta-beta-alpha-beta fold with side chains that stack with RNA bases. A third helix is present during RNA binding in some cases.
The RRM is reviewed in a number of publications.
Human proteins containing this domain
A2BP1;
ACF;
BOLL
Boll may refer to:
*Boll (surname)
*Boll, an obsolete Scottish measure of volume
*BOLL, a protein in humans
* 7873 Böll, a main-belt asteroid
*Boll case, a 1958 International Court of Justice case
*Boll KG, Uwe Boll's personal production company ...
;
BRUNOL4
CUGBP Elav-like family member 4 (CELF4) also known as bruno-like protein 4 (BRUNOL4) is a protein that in humans is encoded by the CELF4 gene.
Function
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif ( ...
;
BRUNOL5;
BRUNOL6;
CCBL2
The Cape Cod Baseball League (CCBL or Cape League) is a collegiate summer baseball wooden bat league located on Cape Cod in the U.S. state of Massachusetts. One of the nation's premier collegiate summer leagues, the league boasts over one thousan ...
;
CGI-96;
CIRBP;
CNOT4;
CPEB2;
CPEB3;
CPEB4;
CPSF7;
CSTF2
Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the ''CSTF2'' gene.
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor ( ...
;
CSTF2T;
CUGBP1;
CUGBP2
CUGBP, Elav-like family member 2, also known as Etr-3 is a protein that in humans is encoded by the ''CELF2'' gene.
Members of the CELF/BRUNOL protein family are RNA-binding proteins and contain two N-terminal RNA recognition motif (RRM) domains, ...
;
D10S102;
DAZ1
Deleted in azoospermia 1, also known as DAZ1, is a protein which in humans is encoded by the ''DAZ1'' gene.
Function
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its e ...
;
DAZ2
Deleted in azoospermia protein 2 is a protein that in humans is encoded by the ''DAZ2'' gene.
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted t ...
;
DAZ3
Deleted in azoospermia protein 3 is a protein that in humans is encoded by the ''DAZ3'' gene.
This gene is a member of the DAZ protein family, DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression ...
;
DAZ4;
DAZAP1
DAZ-associated protein 1 is a protein that in humans is encoded by the ''DAZAP1'' gene.
Function
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infert ...
;
DAZL
Deleted in azoospermia-like is a protein that in humans is encoded by the ''DAZL'' gene.
Function
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of ...
;
DNAJC17;
DND1;
EIF3S4;
EIF3S9;
EIF4B
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the ''EIF4B'' gene.
Interactions
eIF4B has been shown to interact with and stimulate the activity of eIF4A and bind to the eIF3 complex through the eIF3A subu ...
;
EIF4H
Eukaryotic translation initiation factor 4H is a protein that in humans is encoded by the ''EIF4H'' gene.
This gene encodes one of the translation initiation factors, which function to stimulate the initiation of protein synthesis at the level o ...
;
ELAVL1;
ELAVL2
ELAV-like protein 2 is a protein that in humans is encoded by the ''ELAVL2'' gene.
References
Further reading
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*
*
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*
*
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{{gene-9-stub ...
;
ELAVL3;
ELAVL4
HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ''ELAVL4'' gene.
The HuD/ELAVL4 protein is an RNA-binding protein. HuD contains three RRM protein domains
In molecular biology, a protein domain is a ...
;
ENOX1;
ENOX2
ENOX2 is a gene located on the long arm of the X chromosome in humans. The gene encodes the protein Ecto-NOX disulfide-thiol exchanger 2, a member of the NOX family of NADPH oxidases.
Ecto-NOX disulfide-thiol exchanger 2 is a growth-related cell ...
;
EWSR1
RNA-binding protein EWS is a protein that in humans is encoded by the ''EWSR1'' gene on human chromosome 22, specifically 22q12.2. It is one of 3 proteins in the FET protein family. The q22.2 region of chromosome 22 encodes the N-terminal transact ...
;
FUS;
FUSIP1;
G3BP;
G3BP1
Ras GTPase-activating protein-binding protein 1 is an enzyme that in humans is encoded by the ''G3BP1'' gene.
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/ ...
;
G3BP2;
GRSF1;
HNRNPL;
HNRPA0;
HNRPA1
Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the ''HNRNPA1'' gene. Mutations in hnRNP A1 are causative of amyotrophic lateral sclerosis and the syndrome multisystem proteinopathy.
Function
This ge ...
;
HNRPA2B1
Heterogeneous nuclear ribonucleoproteins A2/B1 is a protein that in humans is encoded by the ''HNRNPA2B1'' gene.
Structure
''HNRNPA2B1'' gene contains 12 exons, including a B1 protein specific 36-nucleotide mini-exon. The entire length of intro ...
;
HNRPA3;
HNRPAB
Heterogeneous nuclear ribonucleoprotein A/B, also known as HNRNPAB, is a protein which in humans is encoded by the ''HNRNPAB'' gene. Although this gene is named ''HNRNPAB'' in reference to its first cloning as an RNA binding protein with similarit ...
;
HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2 is a protein that in humans is encoded by the ''HNRNPC'' gene.
It is abnormally expressed in fetuses of both in vitro fertilization, IVF and intracytoplasmic sperm injection, ICSI, which may contribu ...
;
HNRPCL1;
HNRPD;
HNRPDL;
HNRPF
Heterogeneous nuclear ribonucleoprotein F is a protein that in humans is encoded by the ''HNRNPF'' gene.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding ...
;
HNRPH1;
HNRPH2;
HNRPH3;
HNRPL;
HNRPLL;
HNRPM;
HNRPR;
HRNBP1;
HSU53209;
HTATSF1
HIV Tat-specific factor 1 is a protein that in humans is encoded by the ''HTATSF1'' gene.
Function
Whereas most DNA sequence-specific transcription factors increase the rate of initiation and interact with enhancer or promoter DNA, human immun ...
;
IGF2BP1
Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the ''IGF2BP1'' gene.
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homo ...
;
IGF2BP2
Insulin-like growth factor 2 mRNA-binding protein 2 is a protein that in humans is encoded by the ''IGF2BP2'' gene.
This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domai ...
;
IGF2BP3
Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the ''IGF2BP3'' gene.
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth f ...
;
LARP7;
MKI67IP
MKI67 FHA domain-interacting nucleolar phosphoprotein is a protein that in humans is encoded by the ''MKI67IP'' gene.
MKI67 FHA domain-interacting nucleolar phosphoprotein contains an RNA recognition motif (RRM) near to the N-terminus and a F ...
;
MSI1
RNA-binding protein Musashi homolog 1 also known as Musashi-1 is a protein that in humans is encoded by the ''MSI1'' gene.
Function
This gene encodes a protein containing two conserved tandem RNA recognition motifs and functions as an RNA b ...
;
MSI2;
MSSP-2;
MTHFSD;
MYEF2
Myelin expression factor 2 is a protein that in humans is encoded by the MYEF2 gene.
References
Further reading
{{gene-15-stub ...
;
NCBP2;
NCL;
NOL8;
NONO
Nono may refer to:
Places
* Nono, Argentina, a municipality in the Province of Córdoba
* Nono, Ecuador, a parish in the municipality of Quito in the province of Pichincha
* Nono, Illubabor, Oromia (woreda), Ethiopia, or Nono Sele
** Nono, Il ...
;
P14;
PABPC1
Polyadenylate-binding protein 1 is a protein that in humans is encoded by the ''PABPC1'' gene. The protein PABP1 binds mRNA and facilitates a variety of functions such as transport into and out of the nucleus, degradation, translation, and stabili ...
;
PABPC1L;
PABPC3
Polyadenylate-binding protein 3 is a protein that in humans is encoded by the ''PABPC3'' gene. PABPC3 is a member of a larger family of poly(A)-binding proteins in the human genome.
References
Further reading
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*
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*
External ...
;
PABPC4
Polyadenylate-binding protein 4 (PABPC4) is a protein that in humans is encoded by the ''PABPC4'' gene.
Function
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP ...
;
PABPC5
Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene.
Function
This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is though ...
;
PABPN1
Polyadenylate-binding protein 2 (PABP-2) also known as polyadenylate-binding nuclear protein 1 (PABPN1) is a protein that in humans is encoded by the ''PABPN1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word ...
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POLDIP3
Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the ''POLDIP3'' gene.
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and r ...
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PPARGC1;
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the ''PPARGC1A'' gene. PPARGC1A is also known as human accelerated region 20 ( HAR20). It may, therefore, have played a key r ...
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PPARGC1B;
PPIE;
PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4 is an enzyme that in humans is encoded by the ''PPIL4'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ...
;
PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the ''PPRC1'' gene.
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that c ...
;
PSPC1;
PTBP1
Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the ''PTBP1'' gene.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding protei ...
;
PTBP2;
PUF60
Poly(U)-binding-splicing factor PUF60 is a protein that in humans is encoded by the ''PUF60'' gene.
The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of f ...
;
RALY;
RALYL
RNA-binding Raly-like protein is a protein that in humans is encoded by the ''RALYL'' gene.
References
Further reading
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{{gene-8-stub ...
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RAVER1
Ribonucleoprotein, PTB-binding 1 (also known as RAVER1), is a human gene.
References
Further reading
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{{gene-19-stub ...
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RAVER2
Raver or ravers may refer to:
Places
* Raver, Maharashtra, a city in India
* Raver (Vidhan Sabha constituency)
* Raver (Lok Sabha constituency)
People
* Kim Raver (born 1969), American actress
* Lorna Raver (born 1943), American actress
Com ...
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RBM10
RNA-binding motif 10 is a protein that is encoded by the RBM10 gene. This gene maps on the X chromosome at Xp11.23 in humans. RBM10 is a regulator of alternative splicing. Alternative splicing is a process associated with gene expression to produ ...
;
RBM11
Splicing regulator RBM11 is a protein that is encoded by the ''RBM11'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' ...
;
RBM12
RNA-binding protein 12 is a protein that in humans is encoded by the ''RBM12'' gene.
This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for c ...
;
RBM12B
RNA-binding motif protein, Y chromosome, family 1 member A1/C is a protein that in humans is encoded by the ''RBMY1A1'' gene.
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine ...
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RBM14;
RBM15
Putative RNA-binding protein 15 is a protein that in humans is encoded by the ''RBM15'' gene.
It is an RNA-binding protein
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells a ...
;
RBM15B;
RBM16;
RBM17
Splicing factor 45 is a protein that in humans is encoded by the ''RBM17'' gene.
References
Further reading
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{{gene-10-stub ...
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RBM18;
RBM19;
RBM22
Pre-mRNA-splicing factor RBM22 is a protein that in humans is encoded by the ''RBM22'' gene.
References
Further reading
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{{gene-5-stub ...
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RBM23
Probable RNA-binding protein 23 is a protein that in humans is encoded by the ''RBM23'' gene.
Function
This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, l ...
;
RBM24 RBM is a three-letter acronym. It refers to:
* 89.1 Radio Blue Mountains, Radio station in Katoomba, New South Wales
*The Roll Back Malaria (RBM) Partnership, the global framework to implement coordinated action against malaria.
* Restricted Boltzm ...
;
RBM25
RNA-binding protein 25 is a protein that in humans is encoded by the ''RBM25'' gene.
References
Further reading
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{{gene-14-stub ...
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RBM26
RNA-binding protein 26 is a protein that in humans is encoded by the ''RBM26'' gene.
References
Further reading
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*
*
*
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{{gene-13-stub ...
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RBM27 RBM is a three-letter acronym. It refers to:
* 89.1 Radio Blue Mountains, Radio station in Katoomba, New South Wales
*The Roll Back Malaria (RBM) Partnership, the global framework to implement coordinated action against malaria.
* Restricted Boltzm ...
;
RBM28;
RBM3
Putative RNA-binding protein 3 is a protein that in humans is encoded by the ''RBM3'' gene.
Function
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expres ...
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RBM32B;
RBM33
RNA-binding protein 33 is a protein that in humans is encoded by the ''RBM33'' gene.
References
Further reading
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{{gene-7-stub ...
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RBM34
RNA-binding protein 34 is a protein that in humans is encoded by the ''RBM34'' gene.
References
Further reading
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{{gene-1-stub ...
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RBM35A;
RBM35B;
RBM38;
RBM39
RNA-binding protein 39 is a protein that in humans is encoded by the ''RBM39'' gene.
Function
The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it coloca ...
;
RBM4;
RBM41;
RBM42
RNA-binding protein 4 is a protein that in humans is encoded by the ''RBM4'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or '' ...
;
RBM44;
RBM45;
RBM46;
RBM47
RNA binding motif protein 47 is a protein in humans that is encoded by the RBM47 gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ...
;
RBM4B;
RBM5
RNA-binding protein 5 is a protein that in humans is encoded by the ''RBM5'' gene.
References
Further reading
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External links
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{{gene-3-stub ...
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RBM7
RNA-binding motif protein 7 is a protein that in humans is encoded by the ''RBM7'' gene.
Interactions
RBM7 has been shown to interact with SF3B2 and SFRS3
Splicing factor, arginine/serine-rich 3 is a protein that in humans is encoded by t ...
;
RBM8A;
RBM9
RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the ''RBM9'' gene.
Function
Rbfox2 is one of several human genes similar to the ''C. elegans'' gene Fox-1. This gene encodes an RNA binding ...
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RBMS1
RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the ''RBMS1'' gene.
Function
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are cha ...
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RBMS2 RBMS may refer to:
* Rare Books and Manuscripts Section
*River Bend Middle School
Loudoun County Public Schools (LCPS) is a branch of the Loudoun County, Virginia, United States government, and administers public schools in the county. LCPS's h ...
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RBMS3;
RBMX;
RBMX2
Heterogeneous nuclear ribonucleoprotein G is a protein that in humans is encoded by the ''RBMX'' gene.
Function
This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chrom ...
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RBMXL2;
RBMY1A1
RNA-binding motif protein, Y chromosome, family 1 member A1/C is a protein that in humans is encoded by the ''RBMY1A1'' gene.
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, ...
;
RBMY1B;
RBMY1E;
RBMY1F;
RBMY2FP;
RBPMS;
RBPMS2
RNA-binding protein with multiple splicing is a protein that in humans is encoded by the ''RBPMS'' gene.
Function
This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length an ...
;
RDBP;
RNPC3;
RNPC4;
RNPS1
RNA-binding protein with serine-rich domain 1 is a protein that in humans is encoded by the ''RNPS1'' gene.
Function
This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both ...
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ROD1;
SAFB;
SAFB2;
SART3
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the ''SART3'' gene.
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumo ...
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SETD1A
SET domain containing protein 1A (SETD1A) is a protein that serves as a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at the lys4 residue ( K4). SETD1A is highly homologous with SETDB1 ...
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SF3B14;
SF3B4
Splicing factor 3B subunit 4 is a protein that in humans is encoded by the ''SF3B4'' gene.
Function
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA imme ...
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SFPQ;
SFRS1
Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a protein that in humans is encoded by the ''SRSF1'' gene. ASF/SF2 is an essential sequence spec ...
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SFRS10
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (SFRS10), is a protein that in humans is encoded by the ''TRA2B'' gene.
Interactions
TRA2B has ...
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SFRS11
Splicing factor, arginine/serine-rich 11 is a protein that in humans is encoded by the ''SFRS11'' gene.
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. ...
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SFRS12
Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the ''SFRS12'' gene.
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the acti ...
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SFRS15;
SFRS2
Splicing factor, arginine/serine-rich 2 is a protein that in humans is encoded by the ''SFRS2'' gene. MDS-associated splicing factor SRSF2 affects the expression of Class III and Class IV isoforms and perturbs granulopoiesis and SRSF2 P95H promo ...
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SFRS2B
The Scottish Fire and Rescue Service (SFRS; gd, Seirbheis Smàlaidh agus Teasairginn na h-Alba) is the national fire and rescue service of Scotland. It was formed by the merger of eight regional fire services in the country on 1 April 2013. ...
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SFRS3;
SFRS4
Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the ''SFRS4'' gene.
Interactions
SFRS4 has been shown to interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 5 ...
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SFRS5
Splicing factor, arginine/serine-rich 5 is a protein that in humans is encoded by the ''SFRS5'' gene.
References
Further reading
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{{gene-14-stub ...
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SFRS6;
SFRS7
Serine/arginine-rich splicing factor 7 (SRSF7) also known as splicing factor, arginine/serine-rich 7 (SFRS7) or splicing factor 9G8 is a protein that in humans is encoded by the ''SRSF7'' gene.
Function
The protein encoded by this gene is a ...
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SFRS9
Splicing factor, arginine/serine-rich 9, also known as SFRS9, is a human gene encoding an SR protein involved in splice site selection in alternative splicing.
Interactions
SFRS9 has been shown to interact with Y box binding protein 1 and NOL3
...
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SLIRP
Slirp (sometimes capitalized SLiRP) is a software program that emulates a PPP, SLIP, or CSLIP connection to the Internet using a text-based shell account. Its original purpose became largely obsolete as dedicated dial-up PPP connections and b ...
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SLTM;
SNRP70
snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the ''SNRNP70'' gene. snRNP70 is a small nuclear ribonucleoprotein that associates with U1 spliceosomal RNA, forming the U1snRNP a core comp ...
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SNRPA
U1 small nuclear ribonucleoprotein A is a protein that in humans is encoded by the ''SNRPA'' gene.
Interactions
Small nuclear ribonucleoprotein polypeptide A has been shown to interact
Advocates for Informed Choice, dba interACT or int ...
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SNRPB2;
SPEN
Msx2-interacting protein is a protein that in humans is encoded by the ''SPEN'' gene.
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other rep ...
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SR140
Route 140 or Highway 140 may refer to:
Australia
* Hamilton Highway
Canada
* New Brunswick Route 140
* Ontario Highway 140
* Prince Edward Island Route 140
Costa Rica
* National Route 140
Germany
* Bundesautobahn 140
India
* National Highw ...
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SRRP35;
SSB
SSB may refer to:
Organizations
* Scandinavian School of Brussels
* Social Security Board (disambiguation)
* , the Society of Saint Bridget
* Society of the Sisters of Bethany, an Anglican order of sisters
* Society of Systematic Biologists
* , ...
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SYNCRIP
Synaptotagmin-binding, cytoplasmic RNA-interacting protein (SYNCRIP), also known as heterogeneous nuclear ribonucleoprotein (hnRNP) Q or NS1-associated protein-1 (NSAP-1), is a protein that in humans is encoded by the ''SYNCRIP'' gene. As the name ...
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TAF15;
TARDBP
TAR DNA-binding protein 43 (TDP-43, transactive response DNA binding protein 43 kDa) is a protein that in humans is encoded by the ''TARDBP'' gene.
Structure
TDP-43 is 414 amino acid residues long. It consists of 4 domains: an N-terminal d ...
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THOC4
Aly/REF export factor, also known as THO complex subunit 4 is a protein that in humans is encoded by the ''ALYREF'' gene.
The ALYREF gene encodes Aly/REF export factor (ALY; THO complex subunit 4, Tho4; RNA and export factor binding protein 1, ...
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TIA1
TIA1 or Tia1 cytotoxic granule-associated rna binding protein is a 3'UTR mRNA binding protein that can bind the 5'TOP sequence of 5'TOP mRNAs. It is associated with programmed cell death (apoptosis) and regulates alternative splicing of the gen ...
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TIAL1
Nucleolysin TIAR is a protein that in humans is encoded by the ''TIAL1'' gene.
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elem ...
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TNRC4;
TNRC6C;
TRA2A;
TRSPAP1;
TUT1;
U1SNRNPBP;
U2AF1
Splicing factor U2AF 35 kDa subunit is a protein that in humans is encoded by the ''U2AF1'' gene.
Function
This gene belongs to the splicing factor SR family of genes . U2AF1 is a subunit of the U2 Auxiliary Factor complex alongside a larger ...
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U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the ''U2AF2'' gene.
Function
In eukaryotes, the introns in the transcribed pre-mRNA first have to be removed by spliceosome in order to form a mature mRNA. A spliceo ...
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UHMK1
U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the ''UHMK1'' gene.
Function
UHMK1 is a kinase enzyme which phosphorylates the protein stathmin and has an RNA recognition motif of unknown funct ...
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ZCRB1;
ZNF638
Zinc finger protein 638 is a protein that in humans is encoded by the ''ZNF638'' gene.
The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: ...
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ZRSR1
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 is a protein that in humans is encoded by the ''ZRSR1'' gene.
References
Further reading
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Proteins ...
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ZRSR2
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 is a protein that in humans is encoded by the ''ZRSR2'' gene.
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxi ...
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References
External links
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{{InterPro content, IPR000504
Protein domains