E3 ubiquitin-protein ligase NRDP1 is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''RNF41''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. The specific function of this protein has not yet been determined. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Interactions
RNF41 has been shown to
interact with
USP8
Ubiquitin carboxyl-terminal hydrolase 8 is an enzyme that in humans is encoded by the ''USP8'' gene.
Interactions
USP8 has been shown to interact with RNF41 and STAM2
Signal transducing adapter molecule 2 is a protein that in humans is enc ...
.
See also
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RING finger domain
In molecular biology, a RING (short for Really Interesting New Gene) finger domain is a protein structural domain of zinc finger type which contains a C3HC4 amino acid motif which binds two zinc cations (seven cysteines and one histidine arrang ...
References
Further reading
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External links
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RING finger proteins
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