Precision Neuroscience is an American

brain–computer interface A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI), is a direct communication link between the brain's electrical activity and an external device, most commonly a computer or robotic limb. BCIs are often dire ...

(BCI) company based in

New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ...

and with offices in

Santa Clara, California Santa Clara ( ; Spanish language, Spanish for "Clare of Assisi, Saint Clare") is a city in Santa Clara County, California. The city's population was 127,647 at the 2020 United States census, 2020 census, making it the List of cities and towns i ...

, Addison, Texas and

Minneapolis, Minnesota Minneapolis is a city in Hennepin County, Minnesota, United States, and its county seat. With a population of 429,954 as of the 2020 United States census, 2020 census, it is the state's List of cities in Minnesota, most populous city. Locat ...

. The company is building a minimally invasive brain–computer interface. The interface is based on a thin-film microelectrode array that conforms to the brain surface without penetrating the tissue. It can collect hundreds of times more neural data than traditional cortical surface arrays. The procedure to implant the device does not require a craniotomy, and the implantation is designed to be reversible. Precision Neuroscience aims to treat neurological conditions such as spinal cord injury,

stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...

, and neurodegenerative diseases such as

ALS Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or—in the United States—Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and low ...

and

traumatic brain injury A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. TBI can be classified based on severity ranging from mild traumatic brain injury (mTBI/concussion) to severe traumati ...

History

Precision Neuroscience was founded by Benjamin Rapoport, Michael Mager, Demetrios Papageorgiou, and Mark Hettick and was launched in 2021. Rapoport is a neurosurgeon in the

Mount Sinai Health System The Mount Sinai Health System is the largest hospital network in New York City. It was formed in September 2013 by merging the operations of Continuum Health Partners and Mount Sinai Medical Center. The Health System is structured around eight ...

in New York City, where he specializes in minimally invasive surgery. Rapoport received a PhD in electrical engineering and computer science from the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

and a medical degree from

Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...

. Rapoport was previously on the eight-member founding team at

Elon Musk Elon Reeve Musk ( ; born June 28, 1971) is a businessman. He is known for his leadership of Tesla, SpaceX, X (formerly Twitter), and the Department of Government Efficiency (DOGE). Musk has been considered the wealthiest person in th ...

’s brain–computer interface company,

Neuralink Neuralink Corp. is an American transhumanist neurotechnology company that has developed, as of 2024, implantable brain–computer interfaces (BCIs), also known as brain implants. It was founded by Elon Musk and a team of eight scientists and ...

. Rapoport left Neuralink in 2018. Rapoport, along with Michael Mager, an investor and business builder, and a team of experts in areas such as neuroscience,

microfabrication Microfabrication is the process of fabricating miniature structures of micrometre scales and smaller. Historically, the earliest microfabrication processes were used for integrated circuit fabrication, also known as "semiconductor manufacturing" ...

and software launched Precision Neuroscience in 2021. Rapoport is the founding Chief Science Officer at Precision Neuroscience. Mager is the founding Chief Executive Officer. In May 2021, Precision Neuroscience raised a $12 million Series A funding round led by Steadview Capital. In January 2023, the company raised a $41 million Series B funding round led by Forepont Capital Partners. Other investors in Precision Neuroscience include B Capital, Mubadala Capital, Draper Associates, Alumni Ventures, and re.Mind Capital. In October 2023, Precision Neuroscience acquired a microelectromechanical systems

MEMS MEMS (micro-electromechanical systems) is the technology of microscopic devices incorporating both electronic and moving parts. MEMS are made up of components between 1 and 100 micrometres in size (i.e., 0.001 to 0.1 mm), and MEMS devices ...

manufacturing facility near

Dallas, Texas Dallas () is a city in the U.S. state of Texas and the most populous city in the Dallas–Fort Worth metroplex, the List of Texas metropolitan areas, most populous metropolitan area in Texas and the Metropolitan statistical area, fourth-most ...

. In December 2024, Precision raised $104 million in funding through a series C round led, with participation from B Capital and Duquesne Capital Management.

Technology

The company is building a minimally invasive brain–computer interface. The interface, called the Layer 7 Cortical Interface, makes contact with the brain surface using a thin electrode array that conforms to the surface of the brain without damaging brain tissue. The array is one-fifth the thickness of a human hair and contains 1,024 microelectrodes, yielding a spatial resolution hundreds of times higher than traditional electrode arrays. Together with customized supporting electronics and software, the device provides a high-resolution view of cortical activity in real-time. Precision Neuroscience developed a novel minimally invasive surgical procedure to implant the electrode arrays. To implant the device, a surgeon makes a thin slit in the skull, less than a millimeter in width.

Testing

Precision Neuroscience has successfully used the Layer 7 Cortical Interface to record neural signals in animals and in human patients. In June 2023, Precision Neuroscience announced it had performed a pilot human clinical trial in collaboration with the Rockefeller Neuroscience Institute and the Department of Neurosurgery of the West Virginia University School of Medicine. According to WIRED, “the implants were able to read, record, and map electrical activity in part of the patients’ temporal lobes, which helps process sensory input.” In May 2023, the U.S.

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...

granted Precision Neuroscience's system Breakthrough Device designation. As of 2023, Precision is in the process of applying for full FDA clearance for its first-generation product. In March 2024, Precision Neuroscience announced expanded clinical studies at the Icahn School of Medicine in New York City (led by Ignacio Saez) and the Hospital of the University of Pennsylvania in Philadelphia (led by Iahn Cajigas Gonzales). The U.S. FDA granted 510(k) clearance for Precision's Layer 7 Cortical Interface, a high-resolution cortical electrode array, in 2025. The 1,024

electrode An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or a gas). In electrochemical cells, electrodes are essential parts that can consist of a varie ...

array is a core component of Precision's brain-computer interface system and is used to record, monitor and stimulate electrical activity on the brain's surface. The Layer 7 Cortical Interface is authorized for commercial use, with implantation durations of up to 30 days; Precision has implanted Layer 7 on the cerebral cortex of 37 patients, as of April 2025.

References

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External links

Official site
Brain–computer interface Technology companies established in 2021 Companies based in New York City Health care companies established in 2021