PharmaSat
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PharmaSat was a
nanosatellite A small satellite, miniaturized satellite, or smallsat is a satellite of low mass and size, usually under . While all such satellites can be referred to as "small", different classifications are used to categorize them based on mass. Satellites c ...
developed by
NASA Ames Research Center The Ames Research Center (ARC), also known as NASA Ames, is a major NASA research center at Moffett Federal Airfield in California's Silicon Valley. It was founded in 1939 as the second National Advisory Committee for Aeronautics (NACA) laborat ...
which measured the influence of microgravity upon yeast resistance to an antifungal agent. As a follow on to the GeneSat-1 mission, the Ames Small Spacecraft Division conducted the PharmaSat mission in collaboration with industry and local universities. PharmaSat was the first nanosatellite to implement biological science guided by its Principal Investigator. The mission was designed to aid the development of medicines or techniques to enable long-term crewed space travel and habitation.


Background

The PharmaSat mission builds upon technology demonstrated by GeneSat-1, which used a CubeSat to study
microfluidics Microfluidics refers to a system that manipulates a small amount of fluids (10−9 to 10−18 liters) using small channels with sizes of ten to hundreds of micrometres. It is a multidisciplinary field that involves molecular analysis, molecular bi ...
and
optics Optics is the branch of physics that studies the behaviour and properties of light, including its interactions with matter and the construction of optical instruments, instruments that use or Photodetector, detect it. Optics usually describes t ...
in the space environment. It was designed to provide life-support, growth, monitoring, and analysis capabilities for
microorganisms A microorganism, or microbe, is an organism of microscopic size, which may exist in its single-celled form or as a colony of cells. The possible existence of unseen microbial life was suspected from antiquity, with an early attestation in ...
. Based, like GeneSat-1, around a three-unit
CubeSat A CubeSat is a class of small satellite with a form factor of cubes. CubeSats have a mass of no more than per unit,, url=https://static1.squarespace.com/static/5418c831e4b0fa4ecac1bacd/t/5f24997b6deea10cc52bb016/1596234122437/CDS+REV14+2020-07-3 ...
platform; PharmaSat was designed to accomplish five functions in an autonomous free-flying platform: # Provide life support and environmental control for growth of the
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
strain in 48 independent microwells; # Dose the growing yeast with antifungal agent at the appropriate point on the growth curve with three distinct, well-defined dosage levels, plus a zero-dose control; # Track the population of the yeast via optical density of each microwell before, during and after antifungal administration; # Determine well-by-well yeast viability at multiple, well-defined times after antifungal administration using a colorimetric reagent, Alamar Blue; # Telemeter the resulting population and viability data to Earth, along with system status data.


Operations

PharmaSat was launched at 23:55 UTC on 19 May 2009 aboard a Minotaur I
launch vehicle A launch vehicle is typically a rocket-powered vehicle designed to carry a payload (a crewed spacecraft or satellites) from Earth's surface or lower atmosphere to outer space. The most common form is the ballistic missile-shaped multistage ...
from Pad 0B at the Mid-Atlantic Regional Spaceport on
Wallops Island Wallops Island is a island in Accomack County, Virginia, part of the Virginia Barrier Islands that stretch along the eastern seaboard of the United States. It is just south of Chincoteague Island, a popular tourist destination. Wallops Isla ...
. PharmaSat was flown as a secondary payload co-manifested with the
US Air Force The United States Air Force (USAF) is the Air force, air service branch of the United States Department of Defense. It is one of the six United States Armed Forces and one of the eight uniformed services of the United States. Tracing its ori ...
Air Force Research Laboratory The Air Force Research Laboratory (AFRL) is a scientific research and development detachment of the United States Air Force Air Force Materiel Command, Materiel Command dedicated to leading the discovery, development, and integration of direct- ...
's TacSat-3 spacecraft. PharmaSat was successfully inserted into a
low Earth orbit A low Earth orbit (LEO) is an geocentric orbit, orbit around Earth with a orbital period, period of 128 minutes or less (making at least 11.25 orbits per day) and an orbital eccentricity, eccentricity less than 0.25. Most of the artificial object ...
at approximately above the
Earth Earth is the third planet from the Sun and the only astronomical object known to Planetary habitability, harbor life. This is enabled by Earth being an ocean world, the only one in the Solar System sustaining liquid surface water. Almost all ...
, following which it was activated and began transmitting radio signals to two ground control stations. The primary ground station at
SRI International SRI International (SRI) is a nonprofit organization, nonprofit scientific research, scientific research institute and organization headquartered in Menlo Park, California, United States. It was established in 1946 by trustees of Stanford Univer ...
in
Menlo Park, California Menlo Park ( ) is a city at the eastern edge of San Mateo County, California, San Mateo County in the San Francisco Bay Area of California, United States. It is bordered by San Francisco Bay on the north and east; East Palo Alto, California, Eas ...
, transmitted mission data from the satellite to its operators, while a second station was located at
Santa Clara University Santa Clara University is a private university, private Jesuit university in Santa Clara, California, United States. Established in 1851, Santa Clara University is the oldest operating institution of higher learning in California. The university' ...
, whose Robotic Systems Laboratory was responsible for operating the satellite. After establishing contact the satellite was commanded to initiate its experiment, which lasted 96 hours. Once the experiment began, PharmaSat relayed data in near real-time for up to six months. PharmaSat also carried an
amateur radio Amateur radio, also known as ham radio, is the use of the radio frequency radio spectrum, spectrum for purposes of non-commercial exchange of messages, wireless experimentation, self-training, private recreation, radiosport, contesting, and emer ...
beacon, with a frequency of 437.465
megahertz The hertz (symbol: Hz) is the unit of frequency in the International System of Units (SI), often described as being equivalent to one event (or cycle) per second. The hertz is an SI derived unit whose formal expression in terms of SI base ...
, which broadcast spacecraft telemetry. Amateur radio operators were asked to collect data from the spacecraft and provide it to the operators via the Mission Dashboard website. PharmaSat decayed from orbit and reentered the atmosphere on 14 August 2012.


See also

* List of CubeSats


References

{{Orbital launches in 2009 Spacecraft launched in 2009 CubeSats Spacecraft launched by Minotaur rockets Spacecraft which reentered in 2012