A pathologists’ assistant (PA) is a
physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
extender whose expertise lies in
gross examination
Gross processing or "grossing" is the process by which pathology specimens undergo examination with the bare eye to obtain diagnostic information, as well as cutting and tissue sampling in order to prepare material for subsequent microscopic '' ...
of
surgical
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pa ...
specimens as well as performing
forensic
Forensic science, also known as criminalistics, is the application of science to criminal and civil laws, mainly—on the criminal side—during criminal investigation, as governed by the legal standards of admissible evidence and crimin ...
,
medicolegal, and
hospital autopsies.
General overview
PAs work under the indirect or direct supervision of a board certified anatomical
pathologist
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
, who ultimately renders a
diagnosis
Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines, with variations in the use of logic, analytics, and experience, to determine " cause and effect". In systems engin ...
based on the PA's detailed gross examination and/or
tissue submission for microscopic evaluation. Requirements to become a pathologists' assistant include graduation from a National Accrediting Agency for
Clinical Laboratory Sciences (NAACLS) accredited
education program
Education is a purposeful activity directed at achieving certain aims, such as transmitting knowledge or fostering skills and character traits. These aims may include the development of understanding, rationality, kindness, and honesty. Vari ...
and successfully passing the
American Society for Clinical Pathology The American Society for Clinical Pathology (ASCP) is a professional association based in Chicago, Illinois
Illinois ( ) is a state in the Midwestern United States. Its largest metropolitan areas include the Chicago metropolitan area, an ...
(ASCP) certification
exam
An examination (exam or evaluation) or test is an educational assessment intended to measure a test-taker's knowledge, skill, aptitude, physical fitness, or classification in many other topics (e.g., beliefs). A test may be administered verba ...
, which is not legally required in most states. The credentialing is a certification from the ASCP. Some states such as Nevada and New York require a license. All pathologists' assistants are allied health workers who need to be CLIA 88 compliant to perform these high complexity tasks with indirect/direct supervision.
With ongoing changes in
health care
Health care or healthcare is the improvement of health via the prevention, diagnosis, treatment, amelioration or cure of disease, illness, injury, and other physical and mental impairments in people. Health care is delivered by health ...
, a growing elderly population, and a decreasing number of
pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
residents, the PA is in high demand due to their high level of training and contribution to the overall efficiency of the pathology
laboratory
A laboratory (; ; colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Laboratory services are provided in a variety of settings: physici ...
.
In addition to the major responsibilities outlined above, a
pathologist
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...
s' assistant may also perform the following tasks (for a complete list, refer to Article III, Section B of the AAPA Bylaws):
* Frozen sectioning for
intraoperative consultation
* Preparing tissue samples for flow
cytometry
Cytometry is the measurement of number and characteristics of cells. Variables that can be measured by cytometric methods include cell size, cell count, cell morphology (shape and structure), cell cycle phase, DNA content, and the existence or a ...
,
immunohistochemical
Immunohistochemistry (IHC) is the most common application of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to an ...
(IHC) stains,
genetic testing
Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or ...
,
microbiology
Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...
culturing, and for various other laboratory evaluations
* Gross specimen
photography
Photography is the visual art, art, application, and practice of creating durable images by recording light, either electronically by means of an image sensor, or chemically by means of a light-sensitive material such as photographic film. It i ...
* Training PA
fellow
A fellow is a concept whose exact meaning depends on context.
In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements.
Within the context of higher education ...
s, pathology residents, and other pathology lab personnel (as needed)
* Fulfilling roles in
managerial
Management (or managing) is the administration of an organization, whether it is a business, a nonprofit organization, or a government body. It is the art and science of managing resources of the business.
Management includes the activities ...
duties, instructional positions, and supervisory roles
*
Research
Research is "creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness t ...
ing
While many PAs are employed in
hospitals, they may also gain employment in private pathology laboratories/groups,
medical examiner
The medical examiner is an appointed official in some American jurisdictions who is trained in pathology that investigates deaths that occur under unusual or suspicious circumstances, to perform post-mortem examinations, and in some jurisdict ...
's offices,
morgue
A morgue or mortuary (in a hospital or elsewhere) is a place used for the storage of human corpses awaiting identification (ID), removal for autopsy, respectful burial, cremation or other methods of disposal. In modern times, corpses have c ...
s,
government
A government is the system or group of people governing an organized community, generally a state.
In the case of its broad associative definition, government normally consists of legislature, executive, and judiciary. Government ...
or reference laboratories, or
universities
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which ...
, and may be
self-employed
Self-employment is the state of working for oneself rather than an employer. Tax authorities will generally view a person as self-employed if the person chooses to be recognised as such or if the person is generating income for which a tax return ...
and provide
contract
A contract is a legally enforceable agreement between two or more parties that creates, defines, and governs mutual rights and obligations between them. A contract typically involves the transfer of goods, services, money, or a promise to ...
work.
According to a study published in ''Autonomic Pathology'', PAs perform gross examinations on 56.5% of the total number of specimens submitted industry-wide, with a majority being
biopsies
A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a di ...
.
History of profession
The idea of physician extenders was conceived in 1966 by physician-educator
Eugene A. Stead at
Duke University, where the first
physician assistant
A physician assistant or physician associate (PA) is a type of mid-level health care provider. In North America PAs may diagnose illnesses, develop and manage treatment plans, prescribe medications, and may serve as a principal healthcare prov ...
program was established. Three years later, also at Duke, Chairman of Pathology Dr. Thomas Kinney established the first pathologists’ assistant program.
To date, fourteen accredited programs have been established across the
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five ma ...
and
Canada
Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tota ...
.
Education
Programs can apply to be NAACLS accredited. Attending an accredited program is currently the only route to certification by the ASCP-BOC. PathA programs collectively graduate approximately 118
student
A student is a person enrolled in a school or other educational institution.
In the United Kingdom and most commonwealth countries, a "student" attends a secondary school or higher (e.g., college or university); those in primary or elementa ...
s a year. As of 2010, just over 1,400 pathologists’ assistants are in practice.
The programs vary in details, but are two-year programs at the
masters level, and include
didactic
Didacticism is a philosophy that emphasizes instructional and informative qualities in literature, art, and design. In art, design, architecture, and landscape, didacticism is an emerging conceptual approach that is driven by the urgent need t ...
and
clinical exposure. The didactic year commonly includes an education in
clinical anatomy
''Clinical Anatomy'' is a peer-reviewed medical journal that covers anatomy in all its aspects— gross, histologic, developmental, and neurologic—as applied to medical practice. It is the official publication of the American Association of C ...
,
neuroscience
Neuroscience is the science, scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a Multidisciplinary approach, multidisciplinary science that combines physiology, an ...
,
physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...
,
histology
Histology,
also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures vi ...
, pathology, pathologists’ assistant (clinical correlation)- specific courses,
medical terminology, and inter-professional classes. Students then are placed in a clinical setting in affiliated hospitals and medical examiner's offices to learn
prosection A prosection is the dissection of a cadaver (human or animal) or part of a cadaver by an experienced anatomist in order to demonstrate for students anatomic structure. In a dissection, students learn by doing; in a prosection, students learn by ei ...
and autopsy techniques hands-on.
Universities granting pathology assistant degrees include:
#
Drexel University
Drexel University is a private research university with its main campus in Philadelphia, Pennsylvania. Drexel's undergraduate school was founded in 1891 by Anthony J. Drexel, a financier and philanthropist. Founded as Drexel Institute of Ar ...
* ''Master of Science in Pathologists’ Assistant Studies''
#
Duke University* ''
Master of Health Science
The Master of Health Science (MHS/M.H.Sc.) degree is a specialized master's degree. Depending on the department and specific area of study, the MHS degree provides opportunities for advanced study and research (academic MHS programs) or prepares i ...
''
#
Indiana University* ''
Master of Science
A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast ...
''
#
Quinnipiac University
Quinnipiac University () is a private university in Hamden, Connecticut. The university grants undergraduate, graduate, and professional degrees through its College of Arts and Sciences, School of Business, School of Engineering, School of ...
* ''Master of Health Science''
#
Rosalind Franklin University
Rosalind Franklin University of Medicine and Science (RFU) is a private graduate school in North Chicago, Illinois. It has more than 2,000 students in five schools: Chicago Medical School, College of Health Professions, College of Pharmacy, Dr. Wi ...
* ''Master of Science in Pathologists' Assistant Studies''
#
University of Maryland Baltimore* ''Master of Science in Pathology''
#
University of Western Ontario
The University of Western Ontario (UWO), also known as Western University or Western, is a public research university in London, Ontario, Canada. The main campus is located on of land, surrounded by residential neighbourhoods and the Thames Ri ...
* ''Master of Clinical Science in Pathologists'Assistant Studies''
#
Wayne State University
Wayne State University (WSU) is a public research university in Detroit, Michigan. It is Michigan's third-largest university. Founded in 1868, Wayne State consists of 13 schools and colleges offering approximately 350 programs to nearly 25,000 ...
* ''Master of Science in Pathologists' Assistant Studies''
#
West Virginia University*- ''Master of Health Science''
#
University of Calgary
The University of Calgary (U of C or UCalgary) is a public research university located in Calgary, Alberta, Canada. The University of Calgary started in 1944 as the Calgary branch of the University of Alberta, founded in 1908, prior to being inst ...
*- ''Master of Pathologists' Assistant''
#
Loma Linda University
Loma Linda University (LLU) is a private Seventh-day Adventist health sciences university in Loma Linda, California. , the university comprises eight schools
and a Faculty of Graduate Studies. It is a part of the Seventh-day Adventist educat ...
*- ''Master of Health Science/ Pathologists' Assistant''
#
University of Toledo
The University of Toledo (UToledo or UT) is a public research university in Toledo, Ohio. It is the northernmost campus of the University System of Ohio. The university also operates a Health Science campus, which includes the University of ...
**- ''Master of Science in Biomedical Science''
#
Eastern Virginia Medical School
Eastern Virginia Medical School (EVMS) is a public medical school in Norfolk, Virginia
Norfolk ( ) is an independent city in the Commonwealth of Virginia in the United States. Incorporated in 1705, it had a population of 238,005 at the 20 ...
*- ''Master of Pathologists' Assistant''
#
Tulane University
Tulane University, officially the Tulane University of Louisiana, is a private research university in New Orleans, Louisiana. Founded as the Medical College of Louisiana in 1834 by seven young medical doctors, it turned into a comprehensive pu ...
***- ''Master of Science in Anatomic Pathology''
As of 9/1/2017 the programs above have the following status with the National Accrediting Agency for Clinical Laboratory Sciences:
, *, Accredited
, **, Serious Applicant Status
, ***, Submitted documentation to become accredited
Education and certification
Pathologists' assistants have been employed in pathology labs for over 40 years. Formal training programs slowly appeared (there were four nationwide in the late 1990s). NAACLS began accrediting PathA programs in the late 1990s, and then programs slowly continued their transitions from bachelor's to master's programs as their number increased. Prior to ASCP certification, which came about in 2005, the AAPA had a
fellow
A fellow is a concept whose exact meaning depends on context.
In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements.
Within the context of higher education ...
ship status that program trained pathologists' assistants or on-the-job trained (OJT) pathologists' assistants (who could do specific coursework and three years of active employment) could join only based on passing a rigorous exam that parallels the current ASCP
certification exam. The OJT route was eliminated at the end of 2007. The professional association uniting PAs is the American Association of Pathologists' Assistants. Part of their duties as an association is to provide
continuing medical education credits (CME) in order to keep members current on advances and procedures in the field that must be completed every three years in order to maintain ASCP certification.
In Popular Culture
The 2020 novel The Grave Below features a Pathologists’ Assistant as a prominent character.
References
{{reflist
* http://www.pathassist.org
* http://naacls.org/
* https://archive.today/20120713121733/http://rosalindfranklin.edu/dnn/chp/home/CHP/PathologistsAssistant/tabid/1459/Default.aspx
*https://web.archive.org/web/20131113050308/http://www.pathassistconsulting.com/
Pathology