Olfactory receptor 2T11 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''OR2T11''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitters and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Ligands
*
tert-Butylthiol
''tert''-Butylthiol, also known as ''tert''-butyl mercaptan (TBM), and abbreciated ''t''-BuSH, is an organosulfur compound with the formula (CH3)3CSH. This thiol has a strong odor. It is considered a flavoring agent.
Preparation
''tert''-Butylt ...
(the response is enhanced by the presence of ionic
copper
Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
).
*
Ethanethiol
Ethanethiol, commonly known as ethyl mercaptan, is an organosulfur compound with the formula CH3CH2SH. It is a colorless liquid with a distinct odor. Abbreviated EtSH, it consists of an ethyl group (Et), CH3CH2, attached to a thiol group, SH. It ...
(the response is enhanced by the presence of ionic
copper
Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
).
[
* 2-Propenethiol (]allyl mercaptan
Allyl mercaptan (AM) is a small molecule allyl derivative and an organosulfur compound derived from garlic and a few other genus ''Allium
''Allium'' is a large genus of monocotyledonous flowering plants with around 1000 accepted species, makin ...
) (the response is enhanced by the presence of ionic copper
Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
).[
* ]Thietane
Thietane is a heterocyclic compound containing a Saturated and unsaturated compounds, saturated four-membered ring with three carbon atoms and one sulfur atom. Some derivatives are of interest as drugs.
Thietane, and its derivative 2-propylthiet ...
(the response is enhanced by the presence of ionic copper
Copper is a chemical element; it has symbol Cu (from Latin ) and atomic number 29. It is a soft, malleable, and ductile metal with very high thermal and electrical conductivity. A freshly exposed surface of pure copper has a pinkish-orang ...
).[
]
See also
* Olfactory receptor
Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible for the detection of odorants (for example, compounds that have an odor) which give ...
References
Further reading
*
External links
*
{{transmembranereceptor-stub
Olfactory receptors