Neuropsychological assessment
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Over the past three millennia, scholars have attempted to establish connections between localized brain damage and corresponding behavioral changes. A significant advancement in this area occurred between 1942 and 1948, when Soviet neuropsychologist
Alexander Luria Alexander Romanovich Luria (; , ; 16 July 1902 – 14 August 1977) was a Soviet neuropsychology, neuropsychologist, often credited as a father of modern neuropsychology. He developed an extensive and original battery of neuropsychological ...
developed the first systematic neuropsychological assessment, comprising a battery of behavioral tasks designed to evaluate specific aspects of behavioral regulation. During and following the Second World War, Luria conducted extensive research with large cohorts of brain-injured Russian soldiers. Among his most influential contributions was the identification of the critical role played by the frontal lobes of the cerebral cortex in neuroplasticity, behavioral initiation, planning, and organization. To assess these functions, Luria developed a range of tasks—such as the
Go/no-go A go/no-go test is a two-step verification process that uses two boundary conditions, or a binary classification. The test is passed only when the ''go'' condition has been met and also the ''no-go'' condition has failed. The test gives no inform ...
task, "count by 7," hands-clutching, clock-drawing task, repetitive pattern drawing, word associations, and category recall—which have since become standard elements in neuropsychological evaluations and mental status examinations. Due to the breadth and originality of his methodological contributions, Luria is widely regarded as a foundational figure in the field of neuropsychological assessment. His neuropsychological test battery was later adapted in the United States as the Luria-Nebraska neuropsychological battery during the 1970s. Many of the tasks from this battery were subsequently incorporated into contemporary neuropsychological assessments, including the
Mini–mental state examination The mini–mental state examination (MMSE) or Folstein test is a 30-point questionnaire that is used extensively in clinical and research settings to measure cognitive impairment. It is commonly used in medicine and allied health to screen for d ...
(MMSE), which is commonly used for dementia screening. __TOC__


History

Neuropsychological assessment has traditionally been employed to evaluate the degree of impairment in specific cognitive or functional abilities and to assist in identifying potential areas of brain damage resulting from brain injury or neurological illness. With the development of advanced
neuroimaging Neuroimaging is the use of quantitative (computational) techniques to study the neuroanatomy, structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive ...
techniques, the precise localization of space-occupying lesions can now be achieved with greater accuracy, thereby shifting the focus of neuropsychological assessment toward the evaluation of
cognitive Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, ...
and
behavioral Behavior (American English) or behaviour (British English) is the range of actions of individuals, organisms, systems or artificial entities in some environment. These systems can include other systems or organisms as well as the inanimate p ...
functioning. This includes the systematic examination of the impact of brain injury or other neuropathological processes on an individual. A central component of
neuropsychological Neuropsychology is a branch of psychology concerned with how a person's cognition and behavior are related to the brain and the rest of the nervous system. Professionals in this branch of psychology focus on how injuries or illnesses of the brai ...
assessment involves the administration of standardized
neuropsychological test Neuropsychological tests are specifically designed tasks that are used to measure a psychological function known to be linked to a particular brain structure or pathway. Tests are used for cognitive neuropsychology, research into brain function a ...
s, which provide a structured means of evaluating cognitive abilities. However, neuropsychological assessment encompasses more than the mere administration and scoring of these tests and screening instruments. It is critical that such assessments also incorporate an evaluation of the individual's
mental status The mental status examination (MSE) is an important part of the clinical assessment process in neurological and psychiatric practice. It is a structured way of observing and describing a patient's psychological functioning at a given point in ...
, particularly in cases involving suspected
Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...
or other types of
dementia Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform activities of daily living, everyday activities. This typically invo ...
. Cognitive domains typically assessed include orientation, memory and new learning, general intellectual functioning, language abilities, visuoperceptual skills, and
executive function In cognitive science and neuropsychology, executive functions (collectively referred to as executive function and cognitive control) are a set of cognitive processes that support goal-directed behavior, by regulating thoughts and actions thro ...
. Nevertheless, comprehensive clinical neuropsychological assessment extends beyond cognitive evaluation to consider psychological factors, personality characteristics, interpersonal relationships, and the broader contextual and environmental circumstances relevant to the individual. Assessment may be carried out for a variety of reasons, such as: * Clinical evaluation, to understand the pattern of cognitive strengths as well as any difficulties a person may have, and to aid decision making for use in a medical or rehabilitation environment. * Scientific investigation, to examine a hypothesis about the structure and function of cognition to be tested, or to provide information that allows experimental testing to be seen in context of a wider cognitive profile. * Medico-legal assessment, to be used in a court of law as evidence in a legal claim or criminal investigation. Miller outlined three broad goals of neuropsychological assessment. Firstly,
diagnosis Diagnosis (: diagnoses) is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in a lot of different academic discipline, disciplines, with variations in the use of logic, analytics, and experience, to determine " ...
, to determine the nature of the underlying problem. Secondly, to understand the nature of any brain injury or resulting cognitive problem (see neurocognitive deficit) and its impact on the individual, as a means of devising a rehabilitation programme or offering advice as to an individual's ability to carry out certain tasks (for example, fitness to drive, or returning to work). And lastly, assessments may be undertaken to measure change in functioning over time, such as to determine the consequences of a surgical procedure or the impact of a rehabilitation programme over time.


Diagnosis of a neuropsychological disorder

Certain types of damage to the brain will cause behavioral and cognitive difficulties. Psychologists can start screening for these problems by using either one of the following techniques or all of these combined:


History taking

This includes gathering medical history of the patient and their family, presence or absence of developmental milestones, psychosocial history, and character, severity, and progress of any history of complaints. The psychologist can then gauge how to treat the patient and determine if there are any historical determinants for his or her behavior.


Interviewing

Psychologists use structured interviews in order to determine what kind of neurological problem the patient might be experiencing. There are a number of specific interviews, including the Short Portable Mental Status Questionnaire, Neuropsychological Impairment Scale, Patient's Assessment of Own Functioning, and Structured Interview for the Diagnosis of Dementia.


Test-taking

Scores on standardized tests of adequate predictive validity predictor well current and/or future problems.
Standardized tests A standardized test is a Test (assessment), test that is administered and scored in a consistent or standard manner. Standardized tests are designed in such a way that the questions and interpretations are consistent and are administered and scored ...
allow psychologists to compare a person's results with other people's because it has the same components and is given in the same way. It is therefore representative of the person's's behavior and cognition. The results of a standardized test are only part of the jigsaw. Further, multidisciplinary investigations (e.g. neuroimaging, neurological) are typically needed to officially diagnose a brain-injured patient.


Intelligence testing

Testing one's intelligence can also give a clue to whether there is a problem in the brain-behavior connection. The Wechsler Scales are the tests most often used to determine level of intelligence. The variety of scales available, the nature of the tasks, as well as a wide gap in verbal and performance scores can give clues to whether there is a learning disability or damage to a certain area of the brain.


Testing other areas

Other areas are also tested when a patient goes through neuropsychological assessment. These can include
sensory perception Perception () is the organization, identification, and interpretation of sensory information in order to represent and understand the presented information or environment. All perception involves signals that go through the nervous syste ...
, motor functions,
attention Attention or focus, is the concentration of awareness on some phenomenon to the exclusion of other stimuli. It is the selective concentration on discrete information, either subjectively or objectively. William James (1890) wrote that "Atte ...
,
memory Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembe ...
, auditory and visual processing,
language Language is a structured system of communication that consists of grammar and vocabulary. It is the primary means by which humans convey meaning, both in spoken and signed language, signed forms, and may also be conveyed through writing syste ...
,
problem solving Problem solving is the process of achieving a goal by overcoming obstacles, a frequent part of most activities. Problems in need of solutions range from simple personal tasks (e.g. how to turn on an appliance) to complex issues in business an ...
,
planning Planning is the process of thinking regarding the activities required to achieve a desired goal. Planning is based on foresight, the fundamental capacity for mental time travel. Some researchers regard the evolution of forethought - the cap ...
,
organization An organization or organisation (English in the Commonwealth of Nations, Commonwealth English; American and British English spelling differences#-ise, -ize (-isation, -ization), see spelling differences) is an legal entity, entity—such as ...
, speed of processing, and many others. Neuropsychological assessment can test many areas of
cognitive Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses". It encompasses all aspects of intellectual functions and processes such as: perception, attention, thought, ...
and executive functioning to determine whether a patient's difficulty in function and behavior has a neuropsychological basis.


Information gathered from assessment

Tsatsanis and Volkmar assert that neuropsychological assessment can yield valuable insights into the specific nature of a psychological or neurological disorder, thereby informing the development of an appropriate treatment plan. Such assessments assist in clarifying the characteristics of the disorder and in evaluating the cognitive functioning associated with it. Furthermore, neuropsychological evaluations can help clinicians monitor the developmental trajectory of a disorder, enabling the prediction of potential future complications and the formulation of comprehensive treatment strategies. Various forms of assessment may also be utilized to identify an individual's risk for developing specific conditions. However, a single assessment at one point in time may not provide sufficient information for long-term treatment planning, given the potential variability in behavioral and cognitive functioning. Consequently, repeated assessments are often necessary to determine whether the current treatment approach remains appropriate. Through neuropsychological testing, researchers can identify specific brain regions that may be impaired, based on observed cognitive and behavioral patterns.


Benefits of assessment

Neuropsychological assessment serves as a valuable tool in providing an accurate diagnosis, particularly in cases where the clinical presentation is unclear. Such assessments enable psychologists to identify the specific disorder affecting the patient, thereby informing more targeted and effective treatment strategies. These evaluations also assist in determining the severity of cognitive or neurological deficits, facilitating informed decision-making for both clinicians and patients. Additionally, neuropsychological assessments are useful in monitoring the progression of degenerative conditions through repeated evaluations over time. These assessments also have important applications in the field of
forensic psychology Forensic psychology is the application of scientific knowledge and methods (in relation to psychology) to assist in answering legal questions that may arise in criminal, civil, contractual, or other judicial proceedings. Forensic psychology includes ...
, particularly in cases where a defendant's mental competency is under scrutiny due to suspected brain injury or neurological impairment. In such contexts, neuropsychological testing may reveal cognitive deficits that are not detected through neuroimaging. Moreover, it can aid in the identification of malingering, wherein an individual may be feigning symptoms to obtain a reduced sentence. Typically, the administration of neuropsychological tests requires between 6 and 12 hours, depending on the scope and complexity of the evaluation. This timeframe does not include the additional tasks performed by the psychologist, such as scoring, interpretation of results, case formulation, and the preparation of a comprehensive written report.


Qualifications for conducting assessments

Neuropsychological assessments are typically conducted by doctoral-level psychologists (Ph.D. or Psy.D.) who have received specialized training in neuropsychology. These professionals are referred to as clinical neuropsychologists. The qualifications, training requirements, and scope of practice for clinical neuropsychologists are defined by the widely recognized Houston Conference Guidelines. These individuals typically complete postdoctoral training in areas such as neuropsychology, neuroanatomy, and brain function. The majority are licensed psychologists practicing within their respective jurisdictions. Advancements in the field have enabled certain tasks, such as the administration of specific neuropsychological instruments, to be performed by trained professionals known as psychometrists. However, the interpretation of test results and the formulation of clinical conclusions remain under the purview of the supervising clinical neuropsychologist.


See also

* * * * * * * * , such as
psychometrics Psychometrics is a field of study within psychology concerned with the theory and technique of measurement. Psychometrics generally covers specialized fields within psychology and education devoted to testing, measurement, assessment, and rela ...


References


Further reading

* * ** * ** * This standard reference book includes entries by Kimford J. Meador, Ida Sue Baron, Steven J. Loring, Kerry deS. Hamsher, Nils R. Varney, Gregory P. Lee, Esther Strauss, and Tessa Hart. * * This collection of articles for practitioners includes chapters by Linda A. Reddy, Adam S. Weissman, James B. Hale, Allison Waters, Lara J. Farrell, Elizabeth Schilpzand, Susanna W. Chang, Joseph O'Neill, David Rosenberg, Steven G. Feifer, Gurmal Rattan, Patricia D. Walshaw, Carrie E. Bearden, Carmen Lukie, Andrea N. Schneider, Richard Gallagher, Jennifer L. Rosenblatt, Jean Séguin, Mathieu Pilon, Matthew W. Specht, Susanna W. Chang, Kathleen Armstrong, Jason Hangauer, Heather Agazzi, Justin J. Boseck, Elizabeth L. Roberds, Andrew S. Davis, Joanna Thome, Tina Drossos, Scott J. Hunter, Erin L. Steck-Silvestri, LeAdelle Phelps, William S. MacAllister, Jonelle Ensign, Emilie Crevier-Quintin, Leonard F. Koziol, and Deborah E. Budding. * * * ** * **


External links

* {{Neuropsychology tests