In the
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
, the National Malaria Eradication Program (NMEP) was launched in July 1947. By 1951 this federal program—with state and local participation—had reduced the incidence of
malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
in the United States to the point that the program was officially ended.
History
Background
Malaria was originally only endemic in the
Old World
The "Old World" () is a term for Afro-Eurasia coined by Europeans after 1493, when they became aware of the existence of the Americas. It is used to contrast the continents of Africa, Europe, and Asia in the Eastern Hemisphere, previously ...
. ''
Plasmodium vivax
''Plasmodium vivax'' is a protozoal parasite and a human pathogen. This parasite is the most frequent and widely distributed cause of recurring malaria. Although it is less virulent than ''Plasmodium falciparum'', the deadliest of the five huma ...
'' was imported to North America by British settlers, and ''
Plasmodium falciparum
''Plasmodium falciparum'' is a Unicellular organism, unicellular protozoan parasite of humans and is the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female ''Anopheles'' mos ...
'' arrived in the bodies of enslaved Africans. The expansion of agriculture in the North often involved clearing forests and draining swamps, reducing the breeding area for mosquitoes. The opposite happened in parts of the South, as the breeding area increased where rice was grown.

The 1890 US census reported 880 thousand deaths, of which 2.1 percent were due to malaria. This percentage ranged from 0.2 percent in Minnesota and Wyoming to 10.6 percent in Arkansas; see the accompanying figure.

By the 1930s, malaria had become concentrated in 13 southeastern states. In 1940 the
United States Department of War
The United States Department of War, also called the War Department (and occasionally War Office in the early years), was the United States Cabinet department originally responsible for the operation and maintenance of the United States Army, als ...
asked the
Public Health Service
The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services which manages public health, containing nine out of the department's twelve operating divisions. The Assistant Se ...
(PHS) to help organize public health activities near military facilities, most of which were in the South. In the spring of 1941 the PHS assigned its chief malariologist,
Louis L. Williams
Louis L. Williams, Jr., was an American physician. He served with the United States Public Health Service (USPHS) from 1915 to 1953. From 1942 to 1943, he served as the director of the Malaria Control in War Areas, a program which would be succ ...
, Jr., as liaison officer to the Fourth Service Command's headquarters in Atlanta.
Establishment
Early in 1942 the PHS obtained funds for an independent malarial control program for military installations and war industries in 15 southeastern states and the Caribbean. This program was called Malaria Control in War Areas (MCWA). It was led by Williams in Atlanta. The program focused primarily on
larvicide. They started with
Paris green
Paris green (copper(II) acetate triarsenite or copper(II) acetoarsenite) is an arsenic-based organic pigment. As a green pigment it is also known as Mitis green, Schweinfurt green, Sattler green, emerald, Vienna green, Emperor green or Mount ...
. However,
diesel oil
Diesel fuel, also called diesel oil, heavy oil (historically) or simply diesel, is any liquid fuel specifically designed for use in a diesel engine, a type of internal combustion engine in which fuel ignition takes place without a spark as a re ...
soon became the primary larvicide. That was replaced by
DDT starting in 1944.
From its beginning in 1942, this was a cooperative undertaking by federal, state and local health agencies. The CDC's first director,
Justin M. Andrews, was also Georgia's chief malariologist. Its headquarters were in Atlanta, in part because malaria was locally endemic. Offices were located on the sixth floor of the Volunteer Building on
Peachtree Street
Peachtree Street is one of several major streets running through the city of Atlanta, Georgia, United States. Beginning at Five Points (Atlanta), Five Points in downtown Atlanta, it runs North through Midtown Atlanta, Midtown; a few blocks afte ...
. With an annual budget of about $1 million, some 59% of its personnel were engaged in
mosquito
Mosquitoes, the Culicidae, are a Family (biology), family of small Diptera, flies consisting of 3,600 species. The word ''mosquito'' (formed by ''Musca (fly), mosca'' and diminutive ''-ito'') is Spanish and Portuguese for ''little fly''. Mos ...
abatement and habitat control. Among its 369 employees, the main jobs at CDC at this time were
entomology
Entomology (from Ancient Greek ἔντομον (''éntomon''), meaning "insect", and -logy from λόγος (''lógos''), meaning "study") is the branch of zoology that focuses on insects. Those who study entomology are known as entomologists. In ...
and
engineering
Engineering is the practice of using natural science, mathematics, and the engineering design process to Problem solving#Engineering, solve problems within technology, increase efficiency and productivity, and improve Systems engineering, s ...
.
In 1945 a former
US Public Health Service Research Hospital on
Oatland Island, near
Savannah
A savanna or savannah is a mixed woodland-grassland (i.e. grassy woodland) biome and ecosystem characterised by the trees being sufficiently widely spaced so that the canopy does not close. The open canopy allows sufficient light to reach th ...
Georgia was turned into a large MCWA Research Facility. The Oatland Research Facility conducted research on a variety of diseases, including insect and airborne diseases, and developed methods for controlling and preventing the spread of these diseases. One notable achievement of the CDC lab on Oatland Island was the development of the "No-Pest Strip," which was invented at the laboratory and later led to the development of the flea collar. It closed and consolidated with the Atlanta offices in 1973. In 1946, there were only seven medical officers on duty and an early organization chart was drawn, somewhat fancifully, in the shape of a mosquito.
As part of CDC
In 1946,
Joseph Mountin, head of the State Relations Division of the PHS, which included MCWA, obtained the support of the
National Institutes of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
for the creation of a
Communicable Disease Center (CDC), built on the MCWA. That became the National Communicable Disease Center in 1967, the Center for Disease Control in 1970, the Centers (plural) for Disease Control in 1980 and the Centers for Disease Control and Prevention in 1992.
[.]
During the CDC's first few years, more than 6,500,000 homes were sprayed with the
insecticide
Insecticides are pesticides used to kill insects. They include ovicides and larvicides used against insect eggs and larvae, respectively. The major use of insecticides is in agriculture, but they are also used in home and garden settings, i ...
DDT. DDT was applied to the interior surfaces of rural homes or entire premises in counties where malaria was reported to have been prevalent in recent years. In addition, wetland drainage, removal of mosquito breeding sites, and DDT spraying (occasionally from aircraft) were all pursued. In 1947, some 15,000 malaria cases were reported. By the end of 1949, over 4,650,000 housespray applications had been made and the United States was declared free of malaria as a significant public health problem. By 1950, only 2,000 cases were reported.
By 1951, malaria was considered eliminated altogether from the country and the CDC gradually withdrew from active participation in the operational phases of the program, shifting its interest to surveillance. In 1952, CDC participation in eradication operations ceased altogether.
A major international effort along the lines of the NMEP—the
Global Malaria Eradication Programme (1955–1969), administered by the
World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
—was unsuccessful.
See also
*
List of diseases eradicated from the United States
References
Citations and notes
Other sources
* Humphreys, Margaret (2001), ''Malaria: Poverty, Race, and Public Health in the United States'',
Johns Hopkins University Press
Johns Hopkins University Press (also referred to as JHU Press or JHUP) is the publishing division of Johns Hopkins University. It was founded in 1878 and is the oldest continuously running university press in the United States. The press publi ...
.
* Daniel Sledge and George Mohler (2013)
"Eliminating Malaria in the American South," ''American Journal of Public Health''
* Centers for Disease Control and Prevention (2010)
{{Eradication of infectious disease
Malaria organizations
Medical and health organizations based in Georgia (U.S. state)
Organizations established in 1947
Organizations based in Atlanta
Centers for Disease Control and Prevention
1947 establishments in the United States
1952 disestablishments in the United States
Organizations based in DeKalb County, Georgia
Public health organizations based in the United States
Organizations disestablished in 1952