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Marc Trevor Tessier-Lavigne (born December 18, 1959) is a
Canadian-American Canadian Americans is a term that can be applied to American citizens whose ancestry is wholly or partly Canadian, or citizens of either country that hold dual citizenship. The term ''Canadian'' can mean a nationality or an ethnicity. Canadian ...
neuroscientist A neuroscientist (or neurobiologist) is a scientist who has specialised knowledge in neuroscience, a branch of biology that deals with the physiology, biochemistry, psychology, anatomy and molecular biology of neurons, neural circuits, and glial ...
who is the 11th and current president of
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is conside ...
. Previously, he was a professor at the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It ...
and then president of
Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
in New York City. He was formerly executive vice president for research and chief scientific officer at
Genentech Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within ...
. He is a member of the Cure Alzheimer's Fund's Scientific Advisory Board. As of 2021, he is on the boards of directors of Denali Therapeutics and
Regeneron Pharmaceuticals Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. The company was founded in 1988. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to ...
, as well as the scientific advisory boards of Denali Therapeutics and Agios Pharmaceuticals. In 2022, Stanford University opened an investigation into allegations of Tessier-Lavigne's involvement in fabricating results in articles published between 2001 and 2008.


Early life and education

Tessier-Lavigne was born in
Trenton, Ontario Trenton (2001 population 16,770) is a large unincorporated community in Central Ontario in the municipality of Quinte West, Ontario, Canada. Located on the Bay of Quinte, it is the starting point for the Trent-Severn Waterway, which continues n ...
, Canada. He grew up in Europe from ages 7 to 17, where his father was serving with
NATO The North Atlantic Treaty Organization (NATO, ; french: Organisation du traité de l'Atlantique nord, ), also called the North Atlantic Alliance, is an intergovernmental military alliance between 30 member states – 28 European and two N ...
as part of the
Canadian Armed Forces } The Canadian Armed Forces (CAF; french: Forces armées canadiennes, ''FAC'') are the unified military forces of Canada, including sea, land, and air elements referred to as the Royal Canadian Navy, Canadian Army, and Royal Canadian Air Force. ...
. He was the first in his family to attend college. Tessier-Lavigne received a
Bachelor of Science A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University o ...
with a major in
physics Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which ...
from
McGill University McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill Univer ...
in Canada in 1980 and a
Bachelor of Arts Bachelor of arts (BA or AB; from the Latin ', ', or ') is a bachelor's degree awarded for an undergraduate program in the arts, or, in some cases, other disciplines. A Bachelor of Arts degree course is generally completed in three or four yea ...
with a major in
philosophy Philosophy (from , ) is the systematized study of general and fundamental questions, such as those about existence, reason, knowledge, values, mind, and language. Such questions are often posed as problems to be studied or resolved. ...
and
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemic ...
from the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
in
England England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe ...
in 1982. He received a
Doctor of Philosophy A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is ...
in physiology from
University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
in 1987. Tessier-Lavigne attended the University of Oxford on a
Rhodes Scholarship The Rhodes Scholarship is an international postgraduate award for students to study at the University of Oxford, in the United Kingdom. Established in 1902, it is the oldest graduate scholarship in the world. It is considered among the world' ...
, where he "first encountered the
nervous system In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. The nervous system detects environmental changes ...
and fell in love with it," graduating with first-class honor. His
doctoral advisor A doctoral advisor (also dissertation director, dissertation advisor; or doctoral supervisor) is a member of a university faculty whose role is to guide graduate students who are candidates for a doctorate, helping them select coursework, as w ...
at University College London was
David Attwell David Attwell FRS (born 1953ATTWELL, Prof. David Ian
''Who's Who 2015'', A & ...
. He did postdoctoral research at the MRC Developmental Neurobiology Unit at University College London in 1987 and at the Center for Neurobiology and Behavior at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
with
Thomas Jessell Thomas Michael Jessell (2 August 1951 – 28 April 2019) was the Claire Tow Professor of biochemistry and molecular biophysics at Columbia University in New York and a prominent developmental neuroscientist. In 2018, Columbia University announce ...
from 1987 to 1991.


Career

Tessier-Lavigne started his career at the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It ...
from 1991 to 2001 and at
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is conside ...
starting in 2001. Genentech hired him in 2003 as its senior vice president of Research Drug Discovery. He cited the firm's "potential to create breakthrough therapies for unmet medical needs" as his reason for leaving academia.Marc Tessier-Lavigne - Executive Vice President: Research and Chief Scientific Officer
,
Genentech Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within ...
. Accessed September 13, 2010.
His research on the development of the brain has uncovered details of how
Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...
is triggered.Pollock, Andrew
"Genentech Scientist to Lead Rockefeller University"
''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'', September 8, 2010. Accessed September 13, 2010.
In 2011 Tessier-Lavigne joined
Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
as its 10th president, succeeding
Paul Nurse Sir Paul Maxime Nurse (born 25 January 1949) is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute. He was awarded the 2001 Nobel Prize in Physiology or Medicine alo ...
, who returned to Britain to take over as president of the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
. Rockefeller University called Tessier-Lavigne, who supervised a team of 1,400 researchers, the "Board's unanimous first choice for the position".Staff
"Rockefeller University Elects Marc Tessier-Lavigne 10th President"
Rockefeller University The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classif ...
press release dated September 9, 2010.
He would be the first high-ranking science employee to leave Genentech following its acquisition by
Roche F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX ...
in March 2009. The departure of Tessier-Lavigne from Genentech raised concerns that the company — described by ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'' as being "among the most innovative and successful biotechnology companies in the world" — would see a negative effect on its scientific culture. Tessier-Lavigne stated that his choice to leave Genentech was unrelated to the Roche merger and that "this is probably the only job that could have lured me away from Genentech." Russell L. Carson, chairman of the board of trustees at Rockefeller University, said that he had "literally called him cold" to offer him the position and that Tessier-Lavigne had the strong scientific background needed to oversee the 70 independent laboratories that operate within the university and whose heads report directly to the president.
Richard Scheller Richard H. Scheller (born 30 October 1953) is the former Chief Science Officer and Head of Therapeutics at 23andMe and the former Executive Vice President of Research and Early Development at Genentech. He was a professor at Stanford University f ...
, Tessier-Lavigne's superior, called the move "part of the tradition of exchange between academia and Genentech." While it was too early to discuss specific goals, Tessier-Lavigne said that he hoped to work on transforming basic science into treatments for disease. Tessier-Lavigne is also a member of the Xconomists, an ad hoc team of editorial advisors for the tech news and media company,
Xconomy Xconomy is a Boston, Massachusetts–based media company providing news on business, life sciences, and technology{{cite web , title=Company Overview of Xconomy, Inc. , url=https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=3 ...
. On February 4, 2016,
Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is conside ...
announced that Tessier-Lavigne would become Stanford's 11th president, succeeding
John L. Hennessy John Leroy Hennessy (born September 22, 1952) is an American computer scientist, academician and businessman who serves as Chairman of Alphabet Inc. Hennessy is one of the founders of MIPS Computer Systems Inc. as well as Atheros and served as ...
.Staff
/ref> In November 2020 he was appointed an Officer of the
Order of Canada The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the cen ...
, one of that nation's highest honors, "for his groundbreaking contributions to developmental neuroscience, and his renowned academic leadership and strong advocacy of science." In November 2022, Stanford announced that its Board of Trustees would oversee an examination of Tessier-Lavigne's publications, "over allegations that neurobiology papers that he co-authored contain multiple manipulated images". Scientific integrity consultant
Elisabeth Bik Elisabeth Margaretha Harbers-Bik (born 1966) is a Dutch microbiologist and scientific integrity consultant. Bik is known for her work detecting photo manipulation in scientific publications, and identifying over 4,000 potential cases of improper ...
had raised concerns about four papers (in such journals as ''
Science Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence ...
'' and ''
Nature Nature, in the broadest sense, is the physical world or universe. "Nature" can refer to the phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. Although humans are ...
'') that were co-authored by Tessier-Lavigne, findings which were confirmed by ''
The Stanford Daily ''The Stanford Daily'' is the student-run, independent daily newspaper serving Stanford University. ''The Daily'' is distributed throughout campus and the surrounding community of Palo Alto, California, United States. It has published since the U ...
''.


Honours

*Honorary degree,
University of Pavia The University of Pavia ( it, Università degli Studi di Pavia, UNIPV or ''Università di Pavia''; la, Alma Ticinensis Universitas) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one ...
, 2006. *Member of the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, a ...
, elected 2013 *Elected to the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
, 2017. *Appointed an Officer of the
Order of Canada The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the cen ...
, 2020. *Tessier-Lavigne has been also elected a member of the United States
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
and its
Institute of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Eng ...
and as a fellow of the
American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...
, a fellow of the
Royal Society of Canada The Royal Society of Canada (RSC; french: Société royale du Canada, SRC), also known as the Academies of Arts, Humanities and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bil ...
, a fellow of the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
and the
Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to adv ...
in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and ...
, an honorary graduand of
University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
, and an honorary fellow of
New College, Oxford New College is one of the constituent colleges of the University of Oxford in the United Kingdom. Founded in 1379 by William of Wykeham in conjunction with Winchester College as its feeder school, New College is one of the oldest colleges at ...
. *Tessier-Lavigne became an international fellow at the Royal Swedish Academy of Engineering Sciences (IVA) in 2020. *Tessier-Lavigne received the Golden Plate Award of the
American Academy of Achievement The American Academy of Achievement, colloquially known as the Academy of Achievement, is a non-profit educational organization that recognizes some of the highest achieving individuals in diverse fields and gives them the opportunity to meet ...
presented by Awards Council member Justice Anthony Kennedy in 2022.


Personal life

Tessier-Lavigne met his wife, Mary Hynes, as a postdoc at Columbia. They have three children, Christian, Kyle, and Ella.


References

{{DEFAULTSORT:Tessier-Lavigne, Marc 1959 births Living people Alumni of New College, Oxford Alumni of University College London Canadian expatriate academics in the United States Canadian Rhodes Scholars Fellows of the Academy of Medical Sciences (United Kingdom) Fellows of the American Association for the Advancement of Science Canadian Fellows of the Royal Society Fellows of the Royal Society of Canada McGill University Faculty of Science alumni Members of the United States National Academy of Sciences Presidents of Rockefeller University University of California, San Francisco faculty People from Quinte West Canadian neuroscientists Stanford University faculty Stanford University Department of Biology faculty Stanford University School of Medicine faculty Genentech people Pfizer people Presidents of Stanford University Fellows of the American Academy of Arts and Sciences Members of the American Philosophical Society Members of the National Academy of Medicine Officers of the Order of Canada