Misha Mahowald
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Michelle Anne Mahowald (January 12, 1963 – December 26, 1996) was an American computational neuroscientist in the emerging field of
neuromorphic engineering Neuromorphic computing is an approach to computing that is inspired by the structure and function of the human brain. A neuromorphic computer/chip is any device that uses physical artificial neurons to do computations. In recent times, the term ...
. In 1996 she was inducted into the
Women in Technology International Women in Technology International (WITI) is an organization promoting the achievements of women in technology and extending support, opportunities, and inspiration. It was founded by Carolyn Leighton in 1989 as the International Network of Women in ...
Hall of Fame for her development of the Silicon Eye and other computational systems. She died by suicide at age 33.


Early life and education

Michelle, known as Misha, was born in
Minneapolis, Minnesota Minneapolis is a city in Hennepin County, Minnesota, United States, and its county seat. With a population of 429,954 as of the 2020 United States census, 2020 census, it is the state's List of cities in Minnesota, most populous city. Locat ...
, daughter of Alfred and Joan Fischer Mahowald. She had a younger sister, Sheila. After graduating high school, she attended the
California Institute of Technology The California Institute of Technology (branded as Caltech) is a private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of institutes ...
, graduating with a degree in
biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
in 1985. She continued at Caltech as a PhD student in Computation and Neural Systems under the supervision of Professor
Carver Mead Carver Andress Mead (born 1 May 1934) is an American scientist and engineer. He currently holds the position of Gordon and Betty Moore Professor Emeritus of Engineering and Applied Science at the California Institute of Technology (Caltech), ...
, a specialist in VLSI. For her thesis, Mahowald created her own project by combining the fields of biology, computer science, and electrical engineering, to produce the silicon retina.


Career

The silicon retina used analog electrical circuits to mimic the biological functions of
rod cell Rod cells are photoreceptor cells in the retina of the eye that can function in lower light better than the other type of visual photoreceptor, cone cells. Rods are usually found concentrated at the outer edges of the retina and are used in ...
s,
cone cell Cone cells or cones are photoreceptor cells in the retina of the vertebrate eye. Cones are active in daylight conditions and enable photopic vision, as opposed to rod cells, which are active in dim light and enable scotopic vision. Most v ...
s, and other non-photoreceptive cells in the
retina The retina (; or retinas) is the innermost, photosensitivity, light-sensitive layer of tissue (biology), tissue of the eye of most vertebrates and some Mollusca, molluscs. The optics of the eye create a focus (optics), focused two-dimensional ...
of the eye. The invention was not only highly original and potentially useful as a device for restoring sight to the blind, but it was also one of the most eclectic feats of electrical and biological engineering of the time. This remarkable example of engineering earned Mahowald a well-deserved reputation as one of the most famous female engineers of her age. Her work has been considered "the best attempt to date" to develop a stereoscopic vision system. She was awarded a doctorate in
computational neuroscience Computational neuroscience (also known as theoretical neuroscience or mathematical neuroscience) is a branch of  neuroscience which employs mathematics, computer science, theoretical analysis and abstractions of the brain to understand th ...
in 1992, and her invention of the silicon retina and the silicon neuron earned her articles in the prestigious scientific journals ''
Scientific American ''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it, with more than 150 Nobel Pri ...
'' and ''
Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
'', as well as four patents and the Clauser Prize for her dissertation. A revised version of her dissertatio

was subsequently published in book form. Mahowald then re-located to the
University of Oxford The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest un ...
for one year to do a post-doctoral fellowship with eminent neuroscientists Kevan Martin and Rodney Douglas. After the completion of this project, Mahowald moved to
Zürich Zurich (; ) is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zurich. It is in north-central Switzerland, at the northwestern tip of Lake Zurich. , the municipality had 448,664 inhabitants. The ...
to help found the Institute of Neuroinformatics (Institut für Neuroinformatik) at the
University of Zurich The University of Zurich (UZH, ) is a public university, public research university in Zurich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 from the existing colleges of the ...
and
ETH Zurich ETH Zurich (; ) is a public university in Zurich, Switzerland. Founded in 1854 with the stated mission to educate engineers and scientists, the university focuses primarily on science, technology, engineering, and mathematics. ETH Zurich ran ...
, a research institution whose mission is to discover the key principles by which brains work and to implement these in artificial systems that interact intelligently with the real world. In 1996, she was made a member of the Women in Technology International (WITI)
Hall of Fame A hall, wall, or walk of fame is a list of individuals, achievements, or other entities, usually chosen by a group of electors, to mark their excellence or Wiktionary:fame, fame in their field. In some cases, these halls of fame consist of actu ...
. Mahowald died in Zürich at the end of 1996, taking her own life at the age of 33. Aspects of her work and personal life have been described in a book about the creation of the vision sensor company Foveon.


Award

The ''Misha Mahowald Prize for Neuromorphic Engineering'' was created to recognize outstanding achievements in the field of neuromorphic engineering and was first awarded in 2016.Misha Mahowald Prize for Neuromorphic Engineering
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Publications

The following is a list of Misha Mahowald's scientific publications from 1989 onwards. Her name continued to appear on publications after her death in recognition of the strong contributions she had made to those works while still alive.


2000

*R. Hahnloser, R. Sarpeshkar, M. Mahowald, R.J. Douglas and S. Seung: "Digital selection and analog amplification co-exist in an electronic circuit inspired by neocortex", ''Nature'', 405: 947-951, 2000


1999

*R.J. Douglas, C. Koch, M.A. Mahowald and K.A.C. Martin: "Recurrent excitation in neocortical circuits", Cerebral Cortex, Plenum Press, 1999 *R.J. Douglas, M.A. Mahowald and A.M. Whatley: "Strutture di Comunicazione Nei Sistemi Analogici Neuromorfi ommunications Infrastructure for Neuromorphic Analog Systems, Frontiere della Vita, 3: 549-560, D.J. Amit and G. Parisi (Eds.), Enciclopedia Italiana, 1999 *R. Hahnloser, R. Douglas, M. Mahowald and K. Hepp: "Feedback interactions between neuronal pointers and maps for attentional processing", Nature Neuroscience, 2: 746–752, 1999 *P. Häfliger and M. Mahowald: "Weight vector normalization in an analog VLSI artificial neuron using a backpropagating action potential", Learning in silicon, G. Cauwenbergh (Ed.), Kluwer Academics, 1999 *P. Häfliger and M. Mahowald: "Spike based normalizing hebbian learning in an analog VLSI artificial neuron", Analog Integrated Circuits and Signal Processing, 18:(2/3) 133-140, Feb, 1999


1998

*P. Häfliger and M. Mahowald: "Weight vector normalization in an analog VLSI artificial neuron using a backpropagating action potential", Neuromorphic Systems, Engineering Silicon from Neurobiology:16, 191-196, L.S. Smith and A.Hamilton (Eds.), World Scientific, 1998 *C. Rasche, R. Douglas and M. Mahowald, "Characterization of a Pyramidal Silicon Neuron", Neuromorphic Systems: Engineering Silicon from Neurobiology:14, 169-177, L.S. Smith and A. Hamilton (Eds.), World Scientific, 1998


1996

*R. Douglas and M. Mahowald: "Design and fabrication of analog VLSI neurons", Methods in Neuronal Modelling: From Synapses to Networks, C. Koch and I. Segev (Eds.), MIT press, 1996 *R.J. Douglas, M.A. Mahowald and K.A.C. Martin: "Microarchitecture of Neocortical Columns", Brain theory - biological basis and computational principles, 75-95, A. Aertsen and V. Braitenberg (Eds.), Elsevier Science, 1996 *R.J. Douglas, M.A. Mahowald and K.A.C. Martin: "Neuroinformatics as explanatory neuroscience", Neuroimage, 4: 25-28, 1996 *R.J. Douglas, M.A. Mahowald, K.A.C. Martin and K.J. Stratford: "The role of synapses in cortical computation", Journal of Neurocytology, 25: 893-911, 1996 *P. Häfliger, M. Mahowald and L. Watts: "A spike based learning neuron in analog VLSI", Advances in neural information processing systems, 9: 692-698, 1996


1995

*R. Douglas and M. Mahowald: "A Constructor set for Silicon Neurons", An Introduction to Neural and Electronic Networks:14 277-296, S.F. Zornetzer, J.L. Davis, C. Lau and T. McKenna (Eds.), Academic Press, 1995 *R. Douglas and M. Mahowald: "Silicon Neurons", The Handbook of Brain Theory and Neural Networks 282-289, M. Arbib (Ed.), MIT Press, 1995 *R. Douglas, M. Mahowald and C. Mead: "Neuromorphic Analog VLSI", Annual Review of Neuroscience, 18: 255-281, 1995 *R.J. Douglas, C. Koch, M. Mahowald, K.A.C. Martin and H.H. Suarez: "Recurrent Excitation in Neocortical Circuits", Science, 269: 981-985, 1995


1994

*R.J. Douglas, M.A. Mahowald and K.A.C. Martin, "Hybrid analog-digital architectures for neuromorphic systems", Neural Networks, 1994 IEEE World Congress on Computational Intelligence, 3: 1848-1853, IEEE, 1994


1989

*M. Mahowald and T. Delbrück:
Cooperative stereo matching using static and dynamic image features
, ''Analog VLSI Implementation of Neural Systems'', 213-238, C. Mead and M. Ismail (Eds.), Kluwer Academic Publishers, 1989.


References

{{DEFAULTSORT:Mahowald, Misha American neuroscientists 1963 births 1996 suicides 1996 deaths American women neuroscientists 20th-century American women inventors Alumni of the University of Oxford California Institute of Technology alumni Scientists from Minneapolis 20th-century American scientists 20th-century American women scientists 20th-century American inventors Suicides in Switzerland