Poison Ivy
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Poison ivy is a type of allergenic plant in the genus ''
Toxicodendron ''Toxicodendron'' is a genus of flowering plants in the sumac family, Anacardiaceae. It contains trees, shrubs and woody vines, including poison ivy, poison oak, and the lacquer tree. All members of the genus produce the skin-irritating oil ...
'' native to Asia and North America. Formerly considered a single species, ''
Toxicodendron radicans ''Toxicodendron radicans'', commonly known as eastern poison ivy or poison ivy, is a species of allergenic flowering plant. It has numerous subtaxons and forms both vines and shrubs. Despite its common name, it is not a true ivy, but rather a m ...
'', poison ivies are now generally treated as a complex of three separate species: ''T. radicans'', '' T. rydbergii'', and '' T. orientale''. They are well known for causing
urushiol-induced contact dermatitis Urushiol-induced contact dermatitis (also called Toxicodendron dermatitis or Rhus dermatitis) is a type of allergic contact dermatitis caused by the oil urushiol found in various plants, most notably sumac family species of the genus ''Toxicodendr ...
, an itchy, irritating, and sometimes painful rash, in most people who touch them. The rash is caused by
urushiol Urushiol is an oily mixture of organic compounds with Allergic contact dermatitis, allergenic properties found in plants of the Family (biology), family Anacardiaceae, especially ''Toxicodendron'' ''spp.'' (e.g., poison oak, Toxicodendron vernic ...
, a clear liquid compound in the plant's
sap Sap is a fluid transported in the xylem cells (vessel elements or tracheids) or phloem sieve tube elements of a plant. These cells transport water and nutrients throughout the plant. Sap is distinct from latex, resin, or cell sap; it is a s ...
. They are variable in appearance and habit, and despite its common name, it is not a "true" ivy (''
Hedera ''Hedera'', commonly called ivy (plural ivies), is a genus of 12–15 species of evergreen climbing or ground-creeping woody plants in the family Araliaceae, native to Western Europe, Central Europe, Southern Europe, Macaronesia, northwestern ...
''), but rather a member of the
cashew Cashew is the common name of a tropical evergreen tree ''Anacardium occidentale'', in the family Anacardiaceae. It is native to South America and is the source of the cashew nut and the cashew apple, an accessory fruit. The tree can grow as t ...
and
pistachio The pistachio (, ; ''Pistacia vera'') is a small to medium-sized tree of the Anacardiaceae, cashew family, originating in Iran. The tree produces nut (fruit)#Culinary definition and uses, seeds that are widely consumed as food. In 2022, world ...
family (
Anacardiaceae The Anacardiaceae, commonly known as the cashew family or sumac family, are a family of flowering plants, including about 83 genera with about 860 known species. Members of the Anacardiaceae bear fruits that are drupes and in some cases produce ...
). ''T. radicans'' is commonly eaten by many animals, and the seeds are consumed by birds, but poison ivy is most often thought of as an unwelcome
weed A weed is a plant considered undesirable in a particular situation, growing where it conflicts with human preferences, needs, or goals.Harlan, J. R., & deWet, J. M. (1965). Some thoughts about weeds. ''Economic botany'', ''19''(1), 16-24. Pla ...
.


Species

Three species of poison ivy are generally recognised; they are sometimes considered subspecies of ''Toxicodendron radicans'': * '' Toxicodendron orientale'': found in East Asia. * ''
Toxicodendron radicans ''Toxicodendron radicans'', commonly known as eastern poison ivy or poison ivy, is a species of allergenic flowering plant. It has numerous subtaxons and forms both vines and shrubs. Despite its common name, it is not a true ivy, but rather a m ...
'': found throughout eastern Canada and the United States, Mexico and Central America, Bermuda and the Bahamas. * ''
Toxicodendron rydbergii ''Toxicodendron rydbergii'', the western poison ivy or northern poison oak, is a species of '' Toxicodendron'' in the cashew family native to North America. As a poison ivy, it can cause urushiol-induced contact dermatitis. Description Unli ...
'': found throughout Canada and much of the United States except the southeast.


Description

Poison ivies can grow as small plants, shrubs, or climbing vines. They are commonly characterized by clusters of leaves, each containing three leaflets, hence the common expression "leaves of three, let it be". These leaves can vary between an elliptic to egg shape and will have either smooth, lobed, or toothed
margins Margin may refer to: Physical or graphical edges *Margin (typography), the white space that surrounds the content of a page *Continental margin, the zone of the ocean floor that separates the thin oceanic crust from thick continental crust *Leaf ...
. Additionally, the leaf clusters are
alternate Alternative or alternate may refer to: Arts, entertainment and media * Alternative (''Kamen Rider''), a character in the Japanese TV series ''Kamen Rider Ryuki'' * Alternative comics, or independent comics are an alternative to mainstream superh ...
on the stem. Clusters of small, greenish flowers bloom from May to July and produce white berries in the fall a few millimeters in diameter. File:Poison ivy vine.jpg, ''T. radicans'' vine with typical reddish "hairs" File:Toxicodendron radicans 01.jpg, Flower detail, with bee File:Poison ivy-roadside.jpg, Poison ivy on a roadside File:Poison ivy in May beside Appalachian Trail in Rockfish Gap VA area 1.jpg, Leaves may be smooth or notched on the same plant.


Health effects

Urushiol-induced contact dermatitis is the
allergic reaction Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include Allergic rhinitis, hay fever, Food allergy, food al ...
caused by poison ivy. In extreme cases, a reaction can progress to
anaphylaxis Anaphylaxis (Greek: 'up' + 'guarding') is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of the use of emergency medication on site. It typicall ...
. Around 15 to 25 percent of people have no allergic reaction to urushiol, but most people have a greater reaction with repeated or more concentrated exposure. Over 350,000 people are affected by urushiol annually in the United States. The oozing fluids released by scratching blisters do not spread the poison. The fluid in the blisters is produced by the body and it is not urushiol itself. The appearance of a spreading rash indicates that some areas received more of the poison and reacted sooner than other areas or that contamination is still occurring from contact with objects to which the original poison was spread. Those affected can unknowingly spread the urushiol inside the house, on phones, door knobs, couches, counters, desks, and so on, thus in fact repeatedly coming into contact with poison ivy and extending the length of time of the rash. If this happens, the surfaces should be wiped with bleach or a commercial urushiol removal agent. The blisters and oozing result from blood vessels that develop gaps and leak fluid through the skin; if the skin is cooled, the vessels constrict and leak less. If plant material with urushiol is burned and the smoke then inhaled, this rash will appear on the lining of the lungs, causing extreme pain and possibly fatal respiratory difficulty. If poison ivy is eaten, the mucus lining of the mouth and digestive tract can be damaged. Urushiol oil can remain active for several years, so handling dead leaves or vines can cause a reaction. In addition, oil transferred from the plant to other objects (such as pet fur) can cause the rash if it comes into contact with the skin. Clothing, tools, and other objects that have been exposed to oil should be washed to prevent further reactions.


Treatment

Immediate washing with soap and cold water or
rubbing alcohol Rubbing alcohol, known as surgical spirit in the British Pharmacopoeia, refers to a group of denatured alcohol solutions commonly used as topical disinfectant. In addition to its medical applications, rubbing alcohol is employed in various indust ...
may help prevent a reaction. During a reaction, calamine lotion or
diphenhydramine Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. Although generally considered sedating, diphenhydramine can cause paradoxical central nervous system stimulation in some individuals, particula ...
may help mitigate symptoms.
Corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are invo ...
s, either applied to the skin or taken by mouth, may be appropriate in extreme cases. An astringent containing aluminum acetate (such as
Burow's solution Burow's solution is an aqueous solution of aluminium triacetate. It is available in the U.S.A. as an over-the-counter drug for topical administration, with under the brand name Domeboro (Moberg Pharma). The preparation has astringent and antibacte ...
) may also provide relief and soothe the uncomfortable symptoms of the rash. Urushiol binds to the skin on contact where it causes severe itching that develops into reddish inflammation or uncoloured bumps, and then
blister A blister is a small pocket of body fluid (lymph, serum, plasma, blood, or pus) within the upper layers of the skin, usually caused by forceful rubbing (friction), burning, freezing, chemical exposure or infection. Most blisters are filled ...
ing. These
lesions A lesion is any damage or abnormal change in the tissue of an organism, usually caused by injury or diseases. The term ''Lesion'' is derived from the Latin meaning "injury". Lesions may occur in both plants and animals. Types There is no de ...
may be treated with
calamine Calamine, also known as calamine lotion, is a medication made from powdered calamine (mineral), calamine mineral that is used to treat mild itchiness. Conditions treated include sunburn, insect bites, Toxicodendron radicans, poison ivy, poiso ...
lotion,
Burow's solution Burow's solution is an aqueous solution of aluminium triacetate. It is available in the U.S.A. as an over-the-counter drug for topical administration, with under the brand name Domeboro (Moberg Pharma). The preparation has astringent and antibacte ...
compresses, dedicated commercial poison ivy itch creams, or baths to relieve discomfort, though recent studies have shown some traditional medicines to be ineffective.
Over-the-counter Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid pres ...
products to ease itching—or simply oatmeal baths and
baking soda Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda (or simply “bicarb” especially in the UK) is a chemical compound with the formula NaHCO3. It is a salt (chemistry), salt compose ...
—are now recommended by
dermatologists Dermatology is the branch of medicine dealing with the Human skin, skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A List of dermatologists, ...
for the treatment of poison ivy. A plant-based remedy cited to counter urushiol-induced contact dermatitis is
jewelweed ''Impatiens'' is a genus of more than 1,000 species of flowering plants, widely distributed throughout the Northern Hemisphere and the tropics. Together with the genus '' Hydrocera'' (one species), ''Impatiens'' make up the family Balsaminace ...
, though jewelweed extracts had no positive effect in clinical studies. Others argue that prevention of lesions is easy if one practices effective washing, using plain soap, scrubbing with a washcloth, and rinsing three times within 2–8 hours of exposure. The pentadecyl
catechols Catechol ( or ), also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula . It is the ''ortho'' isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amounts. It ...
of the
oleoresin Oleoresins are semi-solid extracts composed of resin and essential or fatty oil, obtained by evaporation of the solvents used for their production. The oleoresin of conifers is known as crude turpentine or gum turpentine, which consists of oil o ...
within the sap of poison ivy and related plants causes the allergic reaction; the plants produce a mixture of pentadecylcatechols, which collectively is called urushiol. After injury, the sap leaks to the surface of the plant where the urushiol becomes a blackish
lacquer Lacquer is a type of hard and usually shiny coating or finish applied to materials such as wood or metal. It is most often made from resin extracted from trees and waxes and has been in use since antiquity. Asian lacquerware, which may be c ...
after contact with oxygen.


Prognosis

Typically, the rash from the urushiol oil lasts about five to twelve days, but in extreme cases it can last a month or more. A urushiol rash usually develops within a week of exposure and can last 1–4 weeks, depending on severity and treatment. In rare cases, urushiol reactions may require hospitalization.


Related species

People who are sensitive to urushiol can also experience a similar rash from
mangoes A mango is an edible stone fruit produced by the tropical tree ''Mangifera indica''. It originated from the region between northwestern Myanmar, Bangladesh, and northeastern India. ''M. indica'' has been cultivated in South and Southeast Asi ...
. Mangoes are in the same family (Anacardiaceae) as poison ivy; the sap of the mango tree and skin of mangoes has a chemical compound similar to urushiol. A related allergenic compound is present in the raw shells of
cashew Cashew is the common name of a tropical evergreen tree ''Anacardium occidentale'', in the family Anacardiaceae. It is native to South America and is the source of the cashew nut and the cashew apple, an accessory fruit. The tree can grow as t ...
s. Similar reactions have been reported occasionally from contact with the related fragrant sumac ('' Rhus aromatica'') and Japanese lacquer tree. These other plants are also in the family Anacardiaceae.


Similar allergenic plants

* '' Gluta spp'' (rengas tree) * '' Lithraea molleoides'' (''aruera'' – South America) * '' Smodingium argutum'' (African poison ivy) * Toxicodendron: ** '' T. pubescens'' (poison oak – eastern) ** '' T. diversilobum'' (poison oak – western) ** '' T. vernix'' (poison sumac) ** '' T. vernicifluum'' (Japanese lacquer tree)


References


External links


Site with extensive photo images of plants and skin rashes
{{Diseases of the skin and subcutaneous tissue Plant common names Toxicodendron