Mex-3 homolog D (C. elegans), also known as MEX3D, is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''MEX3D''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
MEX3D is an RNA binding protein that interacts with
AU-rich elements of
Bcl-2. Upon binding, MEX3D has a negative regulatory action on Bcl-2 expression at the posttranscriptional level.
Structure
MEX3 proteins contain two N-terminal heterogeneous nuclear ribonucleoprotein K homology motifs (
KH domain ) and a
RING domain at the C-terminus.
References
Further reading
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