U6 snRNA-associated Sm-like protein LSm3 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''LSM3''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
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Interactions
LSM3 has been shown to
interact with
LSM2
U6 snRNA-associated Sm-like protein LSm2 is a protein that in humans is encoded by the ''LSM2'' gene.
Function
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 60 ...
and
LSM10
U7 snRNA-associated Sm-like protein LSm10 is a protein that in humans is encoded by the ''LSM10'' gene.
Interactions
LSM10 has been shown to interact with LSM3.
See also
*U7 small nuclear RNA
The U7 small nuclear RNA (U7 snRNA) is an RN ...
.
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References
Further reading
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