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Kenneth Carleton Frazier (born December 17, 1954) is an American business executive. He is executive chairman and former CEO of the pharmaceutical company Merck & Co. (known as MSD outside of North America). After joining Merck & Co. as general counsel, he directed the company's defense against litigation over the anti-inflammatory drug Vioxx. Frazier is the first African American man to lead a major pharmaceutical company (part of the
Fortune 500 The ''Fortune'' 500 is an annual list compiled and published by ''Fortune (magazine), Fortune'' magazine that ranks 500 of the largest United States Joint-stock company#Closely held corporations and publicly traded corporations, corporations by ...
companies). He was elected to the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
in 2018. Frazier was included in ''Time'''s list of the most influential people in the world in 2018 and 2021.


Early life and education

Kenneth Frazier was born on December 17, 1954, in
North Philadelphia North Philadelphia, nicknamed North Philly, is a section of Philadelphia, Pennsylvania. It is immediately north of Center City. Though the full extent of the region is somewhat vague, "North Philadelphia" is regarded as everything north of either ...
. His father, Otis, was a janitor. Frazier has said
Thurgood Marshall Thurgood Marshall (July 2, 1908 – January 24, 1993) was an American civil rights lawyer and jurist who served as an associate justice of the Supreme Court of the United States from 1967 until 1991. He was the Supreme Court's first African-A ...
was one of his heroes growing up. Frazier's mother died when he was twelve years old. He attended Julia R. Masterman School and Northeast High School. After graduating at age 16, he entered
Pennsylvania State University The Pennsylvania State University (Penn State or PSU) is a public state-related land-grant research university with campuses and facilities throughout Pennsylvania. Founded in 1855 as the Farmers' High School of Pennsylvania, Penn State becam ...
. To make extra money in college, he raised tadpoles and newts and sold them to local stores. After earning his B.A. from Penn State, Frazier enrolled at
Harvard Law School Harvard Law School (Harvard Law or HLS) is the law school of Harvard University, a private research university in Cambridge, Massachusetts. Founded in 1817, it is the oldest continuously operating law school in the United States. Each c ...
and graduated in 1978 with a J.D.


Career


Drinker Biddle

After graduating from Harvard, Frazier began his law career with
Drinker Biddle & Reath Faegre Drinker Biddle & Reath, also known as Faegre Drinker, is a full-service international law firm and one of the 50 largest law firms headquartered in the United States. Faegre Drinker provides legal counseling and litigation to a wide range ...
in Philadelphia. In 1991, Esther F. Lardent, head of the Death Penalty Representation Project, asked Frazier to defend death-row inmate James Willie "Bo" Cochran. Cochran had been arrested and accused of murdering an assistant manager at a Birmingham grocery store in 1976. Frazier, then a partner at Drinker Biddle, and two colleagues took the case. In 1995, after 19 years on death row, the United States Courts of Appeals for the Eleventh Circuit overturned Cochran's conviction. In 1997, Cochran was retried and found not guilty. Frazier continued to represent him after leaving Drinker Biddle. During Frazier's law career, he also took four summer sabbaticals to teach trial advocacy in South Africa.


Merck & Co.

As a lawyer at Drinker Biddle, one of Frazier's clients was Merck & Co., the second-largest drug company in the United States. In 1992, he joined Merck's public affairs division as general counsel. Frazier was named senior general counsel in 1999. As general counsel, he was credited with overseeing the company's defense against claims that the anti-inflammatory drug Vioxx had caused heart attacks and strokes. Analysts at the time estimated Merck's liability to range from 20 to 50 billion dollars. Frazier said the case was "the most significant challenge e'dever faced." He chose to fight all cases in court rather than settle them all quickly. The remaining cases were settled in 2007 for $4.85 billion. In 2006, Frazier was promoted to executive vice president in addition to his role as general counsel. He led the company's largest group, Human Health, from 2007 until he was named president of Merck in April 2010. On January 1, 2011, he became CEO and a member of the company's board of directors, replacing former Merck CEO
Richard Clark Richard Clark may refer to: * Richard Clark (dermatologist), American dermatologist * Richard Clark (business executive) (born 1946), president of Merck * Richard Clark (director), British television director * Richard Auldon Clark, American conduc ...
. Frazier is the first African-American to lead a major pharmaceutical company. As CEO, Frazier has directed the company to take financial risks in developing new treatments. In 2013, he prioritized research funding over meeting the year's earnings target. He has placed special emphasis on improving treatments for
Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...
. Frazier's father died from Alzheimer's. Frazier has said he is also motivated at Merck by a desire to improve the lives of people in developing countries. Frazier received a total compensation of $21,387,205 in 2014; $17,023,820 in 2015; and $21,781,200 in 2016. On February 26, 2017, it was reported Frazier owned 600,304 shares of Merck stock worth approximately $37,000,000. Based on stock transactions at Merck alone and his tenure at the company, his net worth is in the hundreds of millions. As of December 31, 2016, Mr. Frazier was eligible for early retirement subsidies under the Qualified Plan and SRP with a pension valued at $26,593,261. In the "annual collaborative report" from Equilar and
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
, Frazier ranked 66th in the May 2015 list of "200 highest-paid CEOs of large publicly traded companies" and seventh in the list of biopharmaceutical executives with the highest total compensation. In July 2016, Frazier sold 60,000 shares of the firm's stock. The stock was sold at an average price of $64.44. In the years 2018, 2019 and 2020 respectively Frazier sold 787,792, 694,698 and 280,000 shares of the firm's stock with a total value at time of sale of $110.23 million. On February 4, 2021, Merck announced that Frazier would be retiring as president and CEO at the end of June, while remaining executive chairman.


Licensing litigation

Merck deceptively obtained the formula to Sovaldi over a conference call with
Pharmasset Pharmasset Inc. was a pharmaceutical company based in Princeton, New Jersey in the United States. The company develops antiviral drugs for HIV (including racivir), hepatitis B (including clevudine, marketed as Levovir), and hepatitis C. In Nove ...
. In March 2004, Pharmasset was willing to reveal details of its formulas on the call because it was led to believe everyone on the call would be subject to the confidentiality agreement. But the participants included Merck patent attorney Phillippe Durette, who wasn't firewalled and was in a position to turn what he heard into a potential goldmine for Merck. Durette lied about being on the conference call under oath and then Merck's legal team advised him to blame it on poor memory. In a deposition, he repeatedly denied having been on the call. He recanted at trial only after he was confronted with notes taken by a Pharmasset employee during the call, proving that he had participated. At that point, he pleaded a faulty memory. Judge Freeman didn't buy it. "It is overwhelmingly clear...," she ruled, "that Dr. Durette sought at every turn to create the false impression that Merck's conduct was aboveboard." She blamed Merck, which she said "sponsored and encouraged" his conduct, then sought to minimize its importance by attributing the fiasco to "the failed memory of a retired employee." Federal Judge Beth Labson Freeman described the company's behavior as "systematic and outrageous deception in conjunction with unethical business practices and litigation misconduct." That conduct included "lying to Pharmasset, misusing Pharmasset's confidential information, breaching confidentiality and firewall agreements, and lying under oath at deposition and trial." In 2017, Merck said it agreed to enter into a settlement and license agreement with Bristol-Myers Squibb Co and
Ono Pharmaceutical is one of the largest pharmaceutical companies in Japan. It is headquartered in Chuo-ku, Osaka, Japan, with its major plants in Higashinari-ku, Osaka, and Fujinomiya, Shizuoka., and its central research institute at Minase, Shimamoto-cho, M ...
Co Ltd to resolve all global patent-infringement litigation related to its cancer drug,
Keytruda Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast canc ...
. Bristol and Ono, which co-developed the first PD-1 antibody called Opdivo, filed the suit against Merck in September 2014, alleging that its sale of Keytruda, also a PD-1 antibody, infringed their patents in markets including the United States, parts of Europe, Australia and Japan. Merck will make an initial payment of $625 million to Bristol and Japan's Ono. The company will also pay a 6.5-percent royalty rate on
Keytruda Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast canc ...
sales from January 2017 to December 2023, and a 2.5-percent rate for the subsequent three years. In the first two months of 2017, sales of Keytruda in the US jumped to roughly $260 million, an 80-percent increase compared with the same period the previous year, according to IMS, a data provider that tracks medicine sales.


Other work

Frazier currently serves on the board of directors of Merck (as executive chairman), the
National Constitution Center The National Constitution Center is a non-profit institution devoted to the Constitution of the United States. On Independence Mall in Philadelphia, Pennsylvania, the center is an interactive museum and a national town hall for constitutional dia ...
, and Eikon Therapeutics. Previously, Frazier served on the board of
ExxonMobil ExxonMobil Corporation (commonly shortened to Exxon) is an American multinational oil and gas corporation headquartered in Irving, Texas. It is the largest direct descendant of John D. Rockefeller's Standard Oil, and was formed on November 3 ...
from 2009 to 2022 and of the
Pharmaceutical Research and Manufacturers of America Pharmaceutical Research and Manufacturers of America (PhRMA, pronounced ), formerly known as the Pharmaceutical Manufacturers Association, is a trade group representing companies in the pharmaceutical industry in the United States. Founded in 195 ...
from 2011 to 2021. Frazier presently is a trustee of Cornerstone Christian Academy in Philadelphia. In November 2011, the Pennsylvania State University board of trustees appointed Frazier (a trustee) to serve as chairman of a special committee investigation into the child sex abuse scandal involving former assistant football coach
Jerry Sandusky Gerald Arthur Sandusky (born January 26, 1944) is an American retired college football coach and convicted serial child molester. Sandusky served as an assistant coach for his entire career, mostly at Pennsylvania State University under Joe ...
and allegations of a cover up by university officials. Frazier was criticized by
Harrisburg Harrisburg is the capital city of the Commonwealth of Pennsylvania, United States, and the county seat of Dauphin County. With a population of 50,135 as of the 2021 census, Harrisburg is the 9th largest city and 15th largest municipality in ...
attorney William Cluck for his handling of the Sandusky scandal, particularly its decision to rely on the Louis Freeh Report, which found emails suggesting that university leaders, including head football coach
Joe Paterno Joseph Vincent Paterno (; December 21, 1926 – January 22, 2012), sometimes referred to as JoePa, was an American college football player, athletic director, and coach. He was the head coach of the Penn State Nittany Lions from 1966 to 2 ...
, knew of reports of Sandusky's sex abuse but failed to report it. At a meeting, when Cluck questioned the Freeh report, Frazier directed a fiery criticism at Cluck and Paterno defenders,Mike Dawson
Penn State trustee Frazier bashes critics, dismisses Paterno report in spat with candidate
''Centre Daily Times'' (March 15, 2013).
saying, "I believe that we are entitled to look at the words and contemporaneous emails and other documents that draw the conclusions that we need to draw as a university. We are not subject to the criminal beyond-a-reasonable-doubt standard ..If you cared about that, you are one of the few people in this country that looks like you who actually believes the O.J. Simpson not guilty verdict was correct. The fact of the matter is, those documents say what they say, and no amount of hand-waving will ever change what those documents say." Frazier twice apologized for the outburst. Frazier is a member of the
American Law Institute The American Law Institute (ALI) is a research and advocacy group of judges, lawyers, and legal scholars established in 1923 to promote the clarification and simplification of United States common law and its adaptation to changing social needs ...
and serves on its council. In May 2013, he delivered the keynote speech at the ALI Annual Dinner. Frazier was a member of President Trump's
American Manufacturing Council The American Manufacturing Council was a group of prominent chief executives set up to advise U.S. President Donald Trump on domestic manufacturing initiatives. It was chaired by Andrew Liveris, CEO of Dow Chemical Company. Following the withdr ...
. He resigned from the Council on August 14, 2017, following the violent 2017 Unite the Right rally in Virginia. In a statement, Frazier said that he objected to Trump's statement that "many sides" were responsible for violence. Frazier stated, "America's leaders must honor our fundamental views by clearly rejecting expressions of hatred, bigotry and group supremacy, which run counter to the American ideal that all people are created equal." On June 1, 2020, Frazier gave an interview with CNBC Squawk Box addressing racial tensions and violence following the
murder of George Floyd On , George Floyd, a 46-year-old black man, was murdered in the U.S. city of Minneapolis by Derek Chauvin, a 44-year-old white police officer. Floyd had been arrested on suspicion of using a counterfeit $20 bill. Chauvin knelt on Floyd's ...
, an unarmed black man who was murdered by the Minneapolis police. In the interview, he mentioned that it could have been him in that situation. In August 2020, Kenneth Frazier and his wife, Andréa Frazier donated $5 million to Jefferson Health to work with
Temple University Temple University (Temple or TU) is a public state-related research university in Philadelphia, Pennsylvania. It was founded in 1884 by the Baptist minister Russell Conwell and his congregation Grace Baptist Church of Philadelphia then calle ...
on a new stroke initiative targeting African-American communities.


See also

* Raymond Gilmartin


References


External links

* {{DEFAULTSORT:Frazier, Kenneth 1954 births Living people American health care chief executives Businesspeople from Pennsylvania Directors of ExxonMobil Fellows of the American Academy of Arts and Sciences Merck & Co. people Harvard Law School alumni Pennsylvania lawyers Pennsylvania State University alumni Members of the American Philosophical Society African-American business executives Chief executives in the pharmaceutical industry