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Konstantin Nikolaevitch Tretiakoff (; December 26, 1892 – 1958) was a Russian
neuropathologist Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the cli ...
. He was born in
Fergana Fergana ( uz-Latn-Cyrl, Fargʻona, Фарғона, ), () or Ferghana, also Farghana is a district-level city and the capital of Fergana Region in eastern Uzbekistan. Fergana is about 320 km east of Tashkent, about 75 km southwest of A ...
,
Uzbekistan , image_flag = Flag of Uzbekistan.svg , image_coat = Emblem of Uzbekistan.svg , symbol_type = Emblem of Uzbekistan, Emblem , national_anthem = "State Anthem of Uzbekistan, State Anthem of the Republ ...
, as a son of military physician, who was member of Pierre Bonvalot's first Pamir expedition. He studied medicine in L'Assistance Publique des Hopitaux de Paris. He received his doctorate in 1919. In his thesis, he described degeneration of the ''
substantia nigra The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. ''Substantia nigra'' is Latin for "black substance", reflecting the fact that parts of the substantia nigra a ...
'' associated with paralysis agitans (Parkinson disease). Tretiakof was first to link this anatomic structure with parkinsonism. Between 1922 and 1926 Tretiakoff worked at the Hospício de Juquery, near the city of São Paulo,
Brazil Brazil, officially the Federative Republic of Brazil, is the largest country in South America. It is the world's List of countries and dependencies by area, fifth-largest country by area and the List of countries and dependencies by population ...
. In 1931, he was appointed Chairman at the new Department of Neuropathology at the Medical Institute in
Saratov Saratov ( , ; , ) is the largest types of inhabited localities in Russia, city and administrative center of Saratov Oblast, Russia, and a major port on the Volga River. Saratov had a population of 901,361, making it the List of cities and tow ...
, USSR, where he spent the rest of his life. In 1910, Fritz Heinrich Lewy discovered what became known as Lewy bodies, and compared them to earlier findings by
Gonzalo Rodríguez Lafora Gonzalo Rodríguez Lafora (25 July 1886 – 27 December 1971) was a Spanish neurology, neurologist and psychiatrist. He was a disciple of Nicolás Achúcarro and Santiago Ramón y Cajal and one of the most brilliant examples of the Spanish Neurol ...
. In 1913, Lafora described another case, and acknowledged Lewy as the discoverer, naming them ''cuerpos intracelulares de Lewy'' (Lewy bodies). Trétiakoff found them in 1919 in the
substantia nigra The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. ''Substantia nigra'' is Latin for "black substance", reflecting the fact that parts of the substantia nigra a ...
of PD brains, called them ''corps de Lewy'' and is credited with the eponym. Eliasz Engelhardt argued in 2017 that Lafora should be credited with the eponym, because he named them six years before Trétiakoff.


References

* {{DEFAULTSORT:Tretiakoff, Konstantin 1892 births 1958 deaths Soviet neurologists Corresponding Members of the USSR Academy of Medical Sciences Lewy body dementia People from Fergana Soviet pathologists Scientists from Saratov