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Sir John Scott Burdon-Sanderson, 1st Baronet, FRS, H
FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This soci ...
D.Sc. Doctor of Science ( la, links=no, Scientiae Doctor), usually abbreviated Sc.D., D.Sc., S.D., or D.S., is an academic research degree awarded in a number of countries throughout the world. In some countries, "Doctor of Science" is the degree used f ...
(21 December 182823 November 1905) was an English
physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
born near
Newcastle upon Tyne Newcastle upon Tyne ( RP: , ), or simply Newcastle, is a city and metropolitan borough in Tyne and Wear, England. The city is located on the River Tyne's northern bank and forms the largest part of the Tyneside built-up area. Newcastle is ...
, and a member of a well known Northumbrian family.


Biography

He was born at
Jesmond Jesmond is a suburb of Newcastle upon Tyne, situated to the east of the Town Moor. Jesmond is considered to be one of the most affluent suburbs of Newcastle upon Tyne, with higher average house prices than most other areas of the city. H ...
near
Newcastle-upon-Tyne Newcastle upon Tyne ( RP: , ), or simply Newcastle, is a city and metropolitan borough in Tyne and Wear, England. The city is located on the River Tyne's northern bank and forms the largest part of the Tyneside built-up area. Newcastle is ...
on 21 December 1828 the son of Richard Burdon (1791-1865) and his wife Elizabeth Sanderson. His maternal grandfather was
Sir James Sanderson, 1st Baronet Sir James Sanderson, 1st Baronet (30 December 1741 – 21 June 1798) was an English banker, a Member of Parliament, an alderman and Lord Mayor of London. He also served as president of Bridewell Hospital (now a school), and was a member of Wil ...
. His paternal grandfather was Sir Thomas Burdon. He received his medical education at the
University of Edinburgh The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1 ...
with the thesis ''"On the metamorphoses of the coloured corpuscles in extravasated blood"'' and at
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. Si ...
. Settling in London, he became
Medical Officer of Health A medical officer of health, also known as a medical health officer, chief health officer, chief public health officer or district medical officer, is the title commonly used for the senior government official of a health department, usually at a m ...
for
Paddington Paddington is an area within the City of Westminster, in Central London. First a medieval parish then a metropolitan borough, it was integrated with Westminster and Greater London in 1965. Three important landmarks of the district are Padd ...
in 1856 and four years later
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
to the
Middlesex Hospital Middlesex Hospital was a teaching hospital located in the Fitzrovia area of London, England. First opened as the Middlesex Infirmary in 1745 on Windmill Street, it was moved in 1757 to Mortimer Street where it remained until it was finally clos ...
and the Brompton Consumption hospitals. When
diphtheria Diphtheria is an infection caused by the bacterium '' Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks more than 10% of those diagnosed with the disease may die. Signs and s ...
appeared in England in 1858 he was sent to investigate the disease at the different points of outbreak, and in subsequent years he carried out a number of similar inquiries, e.g. into the
cattle plague Rinderpest (also cattle plague or steppe murrain) was an infectious viral disease of cattle, domestic buffalo, and many other species of even-toed ungulates, including gaurs, buffaloes, large antelope, deer, giraffes, wildebeests, and warth ...
and into
cholera Cholera is an infection of the small intestine by some strains of the bacterium '' Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting an ...
in 1866. In 1871, he reported that ''Penicillium'' inhibited the growth of bacteria, an observation which places him among the forerunners of
Alexander Fleming Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of what ...
. He became first principal of the Brown Institution at
Lambeth Lambeth () is a district in South London, England, in the London Borough of Lambeth, historically in the County of Surrey. It is situated south of Charing Cross. The population of the London Borough of Lambeth was 303,086 in 2011. The area e ...
in 1871, and in 1874 was appointed
Jodrell Professor of Physiology The Jodrell Chair of Physiology is a chair at University College London, endowed (shortly before the Jodrell Professor of Zoology and Comparative Anatomy) by Thomas Jodrell Phillips Jodrell in 1873. The chairs succeeded the previous chair in Ana ...
at
University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
, retaining that post until 1882. When the Waynflete Chair of Physiology was established at
Oxford Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
in 1882, he was chosen to be its first occupant, and immediately found himself the object of a furious anti-
vivisection Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experiment ...
ist agitation. The proposal that the university should spend a large amount of money providing him with a suitable laboratory, lecture rooms, etc., in which to carry on his work, was strongly opposed, by some on grounds of economy, but largely because he was an upholder of the usefulness and necessity of experiments upon animals. It was, however, eventually carried by a small majority (88 to 85), and in the same year the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
awarded him a
Royal Medal The Royal Medal, also known as The Queen's Medal and The King's Medal (depending on the gender of the monarch at the time of the award), is a silver-gilt medal, of which three are awarded each year by the Royal Society, two for "the most important ...
in recognition of his researches into the electrical phenomena exhibited by plants and the relations of minute organisms to disease, and of the services he had rendered to physiology and
pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
. In 1885 the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
was asked to vote £500 a year for three years for the purposes of the laboratory, then approaching completion. This proposal was fought with the utmost bitterness by Sanderson's opponents, the anti-vivisectionists including E. A. Freeman,
John Ruskin John Ruskin (8 February 1819 20 January 1900) was an English writer, philosopher, art critic and polymath of the Victorian era. He wrote on subjects as varied as geology, architecture, myth, ornithology, literature, education, botany and pol ...
and Bishop Mackarness of Oxford. Ultimately the money was granted by 412 to 244 votes. In 1895 Sanderson was appointed
Regius Professor A Regius Professor is a university professor who has, or originally had, royal patronage or appointment. They are a unique feature of academia in the United Kingdom and Ireland. The first Regius Professorship was in the field of medicine, and ...
of Medicine at Oxford, resigning the post in 1904. In 1899 he was created a
Baronet A baronet ( or ; abbreviated Bart or Bt) or the female equivalent, a baronetess (, , or ; abbreviation Btss), is the holder of a baronetcy, a hereditary title awarded by the British Crown. The title of baronet is mentioned as early as the 14t ...
, of Banbury Road in the Parish of Saint Giles in the City of Oxford. His attainments, both in biology and medicine, brought him many honours. He was Croonian Lecturer to the Royal Society in 1867 and 1877 and to the
Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ...
in 1891. He gave the
Harveian Oration The Harveian Oration is a yearly lecture held at the Royal College of Physicians of London. It was instituted in 1656 by William Harvey, discoverer of the systemic circulation. Harvey made financial provision for the college to hold an annual fea ...
before the College of Physicians in 1878, acted as President of the
British Association The British Science Association (BSA) is a charity and learned society founded in 1831 to aid in the promotion and development of science. Until 2009 it was known as the British Association for the Advancement of Science (BA). The current Chie ...
at
Nottingham Nottingham ( , locally ) is a city and unitary authority area in Nottinghamshire, East Midlands, England. It is located north-west of London, south-east of Sheffield and north-east of Birmingham. Nottingham has links to the legend of Robi ...
in 1893 and served on three Royal Commissions: on Hospitals (1883), on
Tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, ...
, Meat and Milk (1890), and on a University for London (1892). In February 1902 he received the
honorary degree An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or '' ad h ...
Doctor of Science Doctor of Science ( la, links=no, Scientiae Doctor), usually abbreviated Sc.D., D.Sc., S.D., or D.S., is an academic research degree awarded in a number of countries throughout the world. In some countries, "Doctor of Science" is the degree used f ...
(D.Sc.) from the
Victoria University of Manchester The Victoria University of Manchester, usually referred to as simply the University of Manchester, was a university in Manchester, England. It was founded in 1851 as Owens College. In 1880, the college joined the federal Victoria University. Afte ...
, in connection with the 50th jubilee celebrations of the establishment of the university. He died in Oxford on 23 November 1905. He is buried in
Wolvercote Cemetery Wolvercote Cemetery is a cemetery in the parish of Wolvercote and district of Cutteslowe in Oxford, England. Its main entrance is on Banbury Road and it has a side entrance in Five Mile Drive. It has a funeral chapel, public toilets and a small a ...
in Oxford.


Family

In 1853 he married the author Ghetal Herschell, daughter of
Ridley Haim Herschell Ridley Haim Herschell (7 April 1807 – 14 April 1864) was a Polish-born British minister who converted from Judaism to evangelical Christianity. He was a founder of the British Society for the Propagation of the Gospel Among the Jews (1842) and ...
. His wife wrote his biography. They had no children. He was maternal uncle to the scientist
John Scott Haldane John Scott Haldane (; 2 May 1860 – 14/15 March 1936) was a British physician and physiologist famous for intrepid self-experimentation which led to many important discoveries about the human body and the nature of gases. He also experime ...
.


See also

* Discoveries of anti-bacterial effects of penicillium moulds before Fleming


Notes and references


External links


Picture, biography, and bibliography
in the Virtual Laboratory of the Max Planck Institute for the History of Science {{DEFAULTSORT:Burdon-Sanderson, John Scott Sanderson, John Sanderson, John Sanderson Fellows of the Royal Society Royal Medal winners Burials at Wolvercote Cemetery Baronets in the Baronetage of the United Kingdom Regius Professors of Medicine (University of Oxford) Presidents of the British Science Association Academics of University College London Alumni of the University of Edinburgh University of Paris alumni Waynflete Professors of Physiology Physicians of St Mary's Hospital, London Herschell family Jodrell Professors of Physiology British expatriates in France