John Heffernan may refer to:
* John Heffernan (American actor) (1934–2018), American actor
* John Heffernan (British actor) (born 1981), British actor
* John Heffernan (hurler) (born 1963), Irish hurler
* John Heffernan, co-writer of ''Snakes on a Plane''
{{hndis, Heffernan, John