Johannes Fabry (1 June 1860, in Jülich – 29 June 1930, in

Dortmund Dortmund (; ; ) is the third-largest city in North Rhine-Westphalia, after Cologne and Düsseldorf, and the List of cities in Germany by population, ninth-largest city in Germany. With a population of 614,495 inhabitants, it is the largest city ...

) was a German

dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medi ...

. He studied medicine at the universities of

Bern Bern (), or Berne (), ; ; ; . is the ''de facto'' Capital city, capital of Switzerland, referred to as the "federal city".; ; ; . According to the Swiss constitution, the Swiss Confederation intentionally has no "capital", but Bern has gov ...

and

Berlin Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population withi ...

, receiving his doctorate in 1886. Following graduation he trained in dermatology under Joseph Doutrelepont at the

University of Bonn The University of Bonn, officially the Rhenish Friedrich Wilhelm University of Bonn (), is a public research university in Bonn, North Rhine-Westphalia, Germany. It was founded in its present form as the () on 18 October 1818 by Frederick Willi ...

and with Hugo Ribbert in

Zürich Zurich (; ) is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zurich. It is in north-central Switzerland, at the northwestern tip of Lake Zurich. , the municipality had 448,664 inhabitants. The ...

. From 1889 to 1929 he was chief medical officer of the Skin Clinic at the

municipal hospital, which under his guidance, became a leading center for dermatology. His name is associated with " Fabry disease", a rare, inherited metabolic disease characterized by telangiectatic skin lesions,

kidney failure Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney fa ...

and disorders of the

cardiovascular In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...

gastrointestinal The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The tract is the largest of the body's systems, after the cardiovascular system. ...

, and

central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity o ...

s. In 1898 he described dermatological features of the disease in a 13-year-old boy, naming the condition "purpura haemorrhagica nodularis". The disease is also called "Anderson-Fabry disease", named along with British surgeon William Anderson, who independent of Fabry, reviewed the progression of the disease over nearly 20 years in a 39-year-old patient.Anderson-Fabry disease
Who Named It

Works by Fabry associated with Fabry disease

* ''Ein Beitrag zur Kenntnis der Purpura haemorrhagica nodularis (Purpura papulosa haemorrhagica Hebrae)''. Archiv für Dermatologie und Syphilis, Berlin, 1898, 43: 187-200. * ''Ueber einen Fall von Angiokeratoma circumscriptum am linken Oberschenkel''. Dermatologische Zeitschrift, 1915, 22: 1-4. * ''Zur Klinik und Ätiologie der Angiokeratoma''. Archiv für Dermatologie und Syphilis, Berlin, 1916, 123: 294-307. * ''Weiterer Beitrag zur Klinik des Angiokeratoma naeviforme (Naevus angiokeratosus)''. Dermatologische Wochenschrift, Hamburg, 1923, 90: 339.

References

{{DEFAULTSORT:Fabry, Johannes 1860 births 1930 deaths People from Jülich Humboldt University of Berlin alumni University of Bern alumni German dermatologists