Internal Nasal Valve
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The nasal cavity is a large, air-filled space above and behind the
nose A nose is a sensory organ and respiratory structure in vertebrates. It consists of a nasal cavity inside the head, and an external nose on the face. The external nose houses the nostrils, or nares, a pair of tubes providing airflow through the ...
in the middle of the
face The face is the front of the head that features the eyes, nose and mouth, and through which animals express many of their emotions. The face is crucial for human identity, and damage such as scarring or developmental deformities may affect th ...
. The
nasal septum The nasal septum () separates the left and right airways of the Human nose, nasal cavity, dividing the two nostrils. It is Depression (kinesiology), depressed by the depressor septi nasi muscle. Structure The fleshy external end of the nasal s ...
divides the cavity into two cavities, also known as fossae. Each cavity is the continuation of one of the two
nostril A nostril (or naris , : nares ) is either of the two orifices of the nose. They enable the entry and exit of air and other gasses through the nasal cavities. In birds and mammals, they contain branched bones or cartilages called turbinates ...
s. The nasal cavity is the uppermost part of the
respiratory system The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies grea ...
and provides the nasal passage for inhaled air from the
nostril A nostril (or naris , : nares ) is either of the two orifices of the nose. They enable the entry and exit of air and other gasses through the nasal cavities. In birds and mammals, they contain branched bones or cartilages called turbinates ...
s to the
nasopharynx The pharynx (: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the esophagus and trachea (the tubes going down to the stomach and the lungs respectively). It is found in vertebrates and invertebrates, though its ...
and rest of the
respiratory tract The respiratory tract is the subdivision of the respiratory system involved with the process of conducting air to the alveoli for the purposes of gas exchange in mammals. The respiratory tract is lined with respiratory epithelium as respirato ...
. The
paranasal sinuses Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphe ...
surround and drain into the nasal cavity.


Structure

The term "nasal cavity" can refer to each of the two cavities of the nose, or to the two sides combined. The lateral wall of each nasal cavity mainly consists of the
maxilla In vertebrates, the maxilla (: maxillae ) is the upper fixed (not fixed in Neopterygii) bone of the jaw formed from the fusion of two maxillary bones. In humans, the upper jaw includes the hard palate in the front of the mouth. The two maxil ...
. However, there is a deficiency that is compensated for by the perpendicular plate of the
palatine bone In anatomy, the palatine bones (; derived from the Latin ''palatum'') are two irregular bones of the facial skeleton in many animal species, located above the uvula in the throat. Together with the maxilla, they comprise the hard palate. Stru ...
, the
medial pterygoid plate The pterygoid processes of the sphenoid (from Greek ''pteryx'', ''pterygos'', "wing"), one on either side, descend perpendicularly from the regions where the body and the greater wings of the sphenoid bone unite. Each process consists of a med ...
, the
labyrinth of ethmoid The ethmoidal labyrinth or lateral mass of the ethmoid bone consists of a number of thin-walled cellular cavities, the ethmoid air cells, arranged in three groups, anterior, middle, and posterior, and interposed between two vertical plates of bone ...
and the
inferior concha The inferior nasal concha (inferior turbinated bone or inferior turbinal/turbinate) is one of the three paired nasal conchae in the nose. It extends horizontally along the lateral wall of the nasal cavity and consists of a lamina of spongy bon ...
. The
paranasal sinus Paranasal sinuses are a group of four paired skeletal pneumaticity, air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the Ethmoid sinus, ethmoidal sinuses a ...
es are connected to the nasal cavity through small orifices called ostia. Most of these ostia communicate with the nose through the lateral nasal wall, via a semi-lunar depression in it known as the
semilunar hiatus The semilunar hiatus (eg, hiatus semilunaris) is a crescent-shaped/semicircular/ curved slit/groove upon the lateral wall of the nasal cavity at the middle nasal meatus just inferior to the ethmoidal bulla. It is the location of the openings for ...
. The hiatus is bound laterally by a projection known as the uncinate process. This region is called the ostiomeatal complex. The roof of each nasal cavity is formed in its upper third to one half by the
nasal bone The nasal bones are two small oblong bones, varying in size and form in different individuals; they are placed side by side at the middle and upper part of the face and by their junction, form the bridge of the upper one third of the nose. Eac ...
and more inferiorly by the junctions of the upper lateral cartilage and nasal septum. Connective tissue and skin cover the bony and cartilaginous components of the
nasal dorsum The human nose is the first organ of the respiratory system. It is also the principal organ in the olfactory system. The shape of the nose is determined by the nasal bones and the nasal cartilages, including the nasal septum, which separates ...
. The floor of the nasal cavities, which also form the roof of the mouth, is made up by the bones of the hard palate: the horizontal plate of the palatine bone posteriorly and the palatine process of the maxilla anteriorly. The most anterior part of the nasal cavity is the nasal vestibule. The vestibule is enclosed by the
nasal cartilages The nasal cartilages are structures within the nose that provide form and support to the nasal cavity. The nasal cartilages are made up of a flexible material called hyaline cartilage (packed collagen) in the distal portion of the nose. There are f ...
and lined by the same
epithelium Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of man ...
of the
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different ...
(stratified squamous, keratinized). Within the vestibule, this changes into the typical respiratory epithelium that lines the rest of the nasal cavity and
respiratory tract The respiratory tract is the subdivision of the respiratory system involved with the process of conducting air to the alveoli for the purposes of gas exchange in mammals. The respiratory tract is lined with respiratory epithelium as respirato ...
. Inside the
nostril A nostril (or naris , : nares ) is either of the two orifices of the nose. They enable the entry and exit of air and other gasses through the nasal cavities. In birds and mammals, they contain branched bones or cartilages called turbinates ...
s of the vestibule are the nasal hair, which filter dust and other matter that are breathed in. The back of the cavity blends, via the
choanae The choanae (: choana), posterior nasal apertures or internal nostrils are two openings found at the back of the nasal passage between the nasal cavity and the pharynx, in humans and other mammals (as well as crocodilians and most skinks). They ...
, into the
nasopharynx The pharynx (: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the esophagus and trachea (the tubes going down to the stomach and the lungs respectively). It is found in vertebrates and invertebrates, though its ...
. The nasal cavity is divided in two by the vertical
nasal septum The nasal septum () separates the left and right airways of the Human nose, nasal cavity, dividing the two nostrils. It is Depression (kinesiology), depressed by the depressor septi nasi muscle. Structure The fleshy external end of the nasal s ...
. On the side of each nasal cavity are three horizontal outgrowths called
nasal concha In anatomy, a nasal concha (; : conchae; ; Latin for 'shell'), also called a nasal turbinate or turbinal, is a long, narrow, curled shelf of bone tissue, bone that protrudes into the breathing passage of the nose in humans and various other anim ...
e (singular "concha") or turbinates. These turbinates disrupt the airflow, directing air toward the
olfactory epithelium The olfactory epithelium is a specialized epithelium, epithelial tissue inside the nasal cavity that is involved in olfaction, smell. In humans, it measures and lies on the roof of the nasal cavity about above and behind the nostrils. The olfact ...
on the surface of the turbinates and the septum. The
vomeronasal organ The vomeronasal organ (VNO), or Jacobson's organ, is the paired auxiliary olfactory (smell) sense organ located in the soft tissue of the nasal septum, in the nasal cavity just above the roof of the mouth (the hard palate) in various tetrapods ...
is located at the back of the
septum In biology, a septum (Latin language, Latin for ''something that encloses''; septa) is a wall, dividing a Body cavity, cavity or structure into smaller ones. A cavity or structure divided in this way may be referred to as septate. Examples Hum ...
and has a role in
pheromone A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavio ...
detection. The nasal cavity has a nasal valve area that includes an external nasal valve and an internal nasal valve. The external nasal valve is bounded medially by the
columella Lucius Junius Moderatus Columella (, Arabic: ) was a prominent Roman writer on agriculture in the Roman Empire. His in twelve volumes has been completely preserved and forms an important source on Roman agriculture and ancient Roman cuisin ...
, laterally by the
lateral nasal cartilage The lateral nasal cartilage (upper lateral cartilage, lateral process of septal nasal cartilage) is situated below the inferior margin of the nasal bone, and is flattened, and triangular in shape. Its anterior margin is thicker than the posterior ...
, and posteriorly by the nasal sill. The internal nasal valve is bounded laterally by the caudal border of the lateral nasal cartilage, medially by the dorsal
nasal septum The nasal septum () separates the left and right airways of the Human nose, nasal cavity, dividing the two nostrils. It is Depression (kinesiology), depressed by the depressor septi nasi muscle. Structure The fleshy external end of the nasal s ...
, and inferiorly by the anterior border of the
inferior turbinate The inferior nasal concha (inferior turbinated bone or inferior turbinal/turbinate) is one of the three paired nasal conchae in the nose. It extends horizontally along the lateral wall of the nasal cavity and consists of a lamina of spongy bon ...
. The internal nasal valve is the narrowest region of the nasal cavity and is the primary site of nasal resistance.


Segments

The nasal cavity is divided into two segments: the respiratory segment and the olfactory segment. * The respiratory segment comprises most of each nasal cavity, and is lined with ciliated pseudostratified columnar epithelium (also called
respiratory epithelium Respiratory epithelium, or airway epithelium, is ciliated pseudostratified columnar epithelium a type of columnar epithelium found lining most of the respiratory tract as respiratory mucosa, where it serves to moisten and protect the airways ...
). The conchae, or turbinates, are located in this region. The turbinates have a very vascularized lamina propria (erectile tissue) allowing the venous plexuses of their mucosa to engorge with blood, restricting airflow and causing air to be directed to the other side of the nose, which acts in concert by shunting blood out of its turbinates. This cycle occurs approximately every two and a half hours. * The olfactory segment is lined with a specialized type of pseudostratified columnar epithelium, known as
olfactory epithelium The olfactory epithelium is a specialized epithelium, epithelial tissue inside the nasal cavity that is involved in olfaction, smell. In humans, it measures and lies on the roof of the nasal cavity about above and behind the nostrils. The olfact ...
, which contains
receptors Receptor may refer to: *Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds ...
for the sense of the smell. This segment is located in and beneath the mucosa of the roof of each nasal cavity and the medial side of each middle turbinate. Histological sections appear yellowish-brown due to the presence of lipofuscin pigments. Olfactory mucosal cell types include bipolar neurons, supporting (sustentacular) cells, basal cells, and
Bowman's glands Olfactory glands, also known as Bowman's glands, are a type of nasal gland situated in the part of the olfactory mucosa beneath the olfactory epithelium, that is the lamina propria, a connective tissue also containing fibroblasts, blood vessels ...
. The axons of the bipolar neurons form the
olfactory nerve The olfactory nerve, also known as the first cranial nerve, cranial nerve I, or simply CN I, is a cranial nerve that contains sensory nerve fibers relating to the sense of smell. The afferent nerve fibers of the olfactory receptor neurons t ...
(cranial nerve I) which enters the brain through the
cribriform plate In mammalian anatomy, the cribriform plate (Latin for lit. '' sieve-shaped''), horizontal lamina or lamina cribrosa is part of the ethmoid bone. It is received into the ethmoidal notch of the frontal bone and roofs in the nasal cavities. It s ...
. Bowman's glands are serous glands in the lamina propria, whose secretions trap and dissolve odoriferous substances.


Blood supply

There is a rich blood supply to the nasal cavity. Blood supply comes from branches of both the
internal Internal may refer to: *Internality as a concept in behavioural economics *Neijia, internal styles of Chinese martial arts *Neigong or "internal skills", a type of exercise in meditation associated with Daoism * ''Internal'' (album) by Safia, 2016 ...
and
external carotid artery The external carotid artery is the major artery of the head and upper neck. It arises from the common carotid artery. It terminates by splitting into the superficial temporal and maxillary artery within the parotid gland. Structure Origin T ...
, including branches of the
facial artery The facial artery, formerly called the external maxillary artery, is a branch of the external carotid artery that supplies blood to superficial structures of the medial regions of the face. Structure The facial artery arises in the carotid t ...
and
maxillary artery The maxillary artery (eg, internal maxillary artery) supplies deep structures of the face. It branches from the external carotid artery just deep to the neck of the mandible. Structure The maxillary artery, the larger of the two terminal branches ...
. The named arteries of the nose are: *
Sphenopalatine artery The sphenopalatine artery (nasopalatine artery) is an artery of the head, commonly known as the artery of epistaxis. It passes through the sphenopalatine foramen to reach the nasal cavity. It is the main artery of the nasal cavity. Course The sp ...
and
greater palatine artery The greater palatine artery is a branch of the descending palatine artery (a terminal branch of the maxillary artery) and contributes to the blood supply of the hard palate and nasal septum. Course The descending palatine artery branches off of ...
, branches of the
maxillary artery The maxillary artery (eg, internal maxillary artery) supplies deep structures of the face. It branches from the external carotid artery just deep to the neck of the mandible. Structure The maxillary artery, the larger of the two terminal branches ...
. *
Anterior ethmoidal artery The anterior ethmoidal artery is a branch of the ophthalmic artery in the orbit. It exits the orbit through the anterior ethmoidal foramen alongside the anterior ethmoidal nerve. It contributes blood supply to the ethmoid sinuses, frontal sinuses, ...
and
posterior ethmoidal artery The posterior ethmoidal artery is an artery of the head which arises from the ophthalmic artery to supply the posterior ethmoidal air cells, and the meninges. It is smaller than the anterior ethmoidal artery. Anatomy Origin The posterior et ...
, branches of the
ophthalmic artery The ophthalmic artery (OA) is an artery of the head. It is the first branch of the internal carotid artery distal to the cavernous sinus. Branches of the ophthalmic artery supply all the structures in the orbit around the eye, as well as some ...
*Septal branches of the
superior labial artery The superior labial artery (superior labial branch of facial artery) is larger and more egregious than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the orbiculari ...
, a branch of the
facial artery The facial artery, formerly called the external maxillary artery, is a branch of the external carotid artery that supplies blood to superficial structures of the medial regions of the face. Structure The facial artery arises in the carotid t ...
, which supplies the vestibule of the nasal cavity.


Nerve supply

Innervation A nerve is an enclosed, cable-like bundle of nerve fibers (called axons). Nerves have historically been considered the basic units of the peripheral nervous system. A nerve provides a common pathway for the electrochemical nerve impulses called ...
of the nasal cavity responsible for the
sense of smell The sense of smell, or olfaction, is the special sense through which smells (or odors) are perceived. The sense of smell has many functions, including detecting desirable foods, hazards, and pheromones, and plays a role in taste. In humans, it ...
is via the
olfactory nerve The olfactory nerve, also known as the first cranial nerve, cranial nerve I, or simply CN I, is a cranial nerve that contains sensory nerve fibers relating to the sense of smell. The afferent nerve fibers of the olfactory receptor neurons t ...
, which sends microscopic fibers from the
olfactory bulb The olfactory bulb (Latin: ''bulbus olfactorius'') is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex (OF ...
through the
cribriform plate In mammalian anatomy, the cribriform plate (Latin for lit. '' sieve-shaped''), horizontal lamina or lamina cribrosa is part of the ethmoid bone. It is received into the ethmoidal notch of the frontal bone and roofs in the nasal cavities. It s ...
to reach the top of the nasal cavity. General sensory innervation is by branches of the
trigeminal nerve In neuroanatomy, the trigeminal nerve (literal translation, lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for Sense, sensation in the face and motor functions ...
(V1 and V2): *
Nasociliary nerve The nasociliary nerve is a branch of the ophthalmic nerve (CN V1) (which is in turn a branch of the trigeminal nerve (CN V)). It is intermediate in size between the other two branches of the ophthalmic nerve, the frontal nerve and lacrimal ner ...
(V1) *
Anterior ethmoidal nerve The anterior ethmoidal nerve is a nerve of the head. It is a branch of the nasociliary nerve (itself a branch of the ophthalmic nerve (V1)). It arises in the orbit, and enters first the cranial cavity and then the nasal cavity. It provides sensor ...
from the nasociliary nerve (V1) *Posterior nasal branches of
maxillary nerve In neuroanatomy, the maxillary nerve (V) is one of the three branches or divisions of the trigeminal nerve, the fifth (CN V) cranial nerve. It comprises the principal functions of Sense, sensation from the maxilla, nasal cavity, Sinus (anatomy ...
(V2) The nasal cavity is innervated by autonomic fibers. Sympathetic innervation to the blood vessels of the mucosa causes them to constrict, while the control of secretion by the mucous glands is carried on
postganglionic In the autonomic nervous system, nerve fibers from the ganglion to the wikt:effector, effector organ are called postganglionic nerve fibers. Neurotransmitters The neurotransmitters of postganglionic fibers differ: * In the parasympathetic div ...
parasympathetic The parasympathetic nervous system (PSNS) is one of the three divisions of the autonomic nervous system, the others being the sympathetic nervous system and the enteric nervous system. The autonomic nervous system is responsible for regulat ...
nerve fibers originating from the
facial nerve The facial nerve, also known as the seventh cranial nerve, cranial nerve VII, or simply CN VII, is a cranial nerve that emerges from the pons of the brainstem, controls the muscles of facial expression, and functions in the conveyance of ta ...
.


Function

The two nasal cavities condition the air to be received by the other areas of the
respiratory tract The respiratory tract is the subdivision of the respiratory system involved with the process of conducting air to the alveoli for the purposes of gas exchange in mammals. The respiratory tract is lined with respiratory epithelium as respirato ...
. Owing to the large surface area provided by the
nasal concha In anatomy, a nasal concha (; : conchae; ; Latin for 'shell'), also called a nasal turbinate or turbinal, is a long, narrow, curled shelf of bone tissue, bone that protrudes into the breathing passage of the nose in humans and various other anim ...
e (also known as turbinates), the air passing through the nasal cavity is warmed or cooled to within 1 degree of
body temperature Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature ...
. In addition, the air is humidified, and dust and other particulate matter is removed by nasal hair in the nostrils. The entire mucosa of the nasal cavity is covered by a blanket of mucus, which lies superficial to the microscopic cilia and also filters inspired air. The
cilia The cilium (: cilia; ; in Medieval Latin and in anatomy, ''cilium'') is a short hair-like membrane protrusion from many types of eukaryotic cell. (Cilia are absent in bacteria and archaea.) The cilium has the shape of a slender threadlike proj ...
of the
respiratory epithelium Respiratory epithelium, or airway epithelium, is ciliated pseudostratified columnar epithelium a type of columnar epithelium found lining most of the respiratory tract as respiratory mucosa, where it serves to moisten and protect the airways ...
move the secreted mucus and particulate matter posteriorly towards the
pharynx The pharynx (: pharynges) is the part of the throat behind the human mouth, mouth and nasal cavity, and above the esophagus and trachea (the tubes going down to the stomach and the lungs respectively). It is found in vertebrates and invertebrates ...
where it passes into the
esophagus The esophagus (American English), oesophagus (British English), or œsophagus (Œ, archaic spelling) (American and British English spelling differences#ae and oe, see spelling difference) all ; : ((o)e)(œ)sophagi or ((o)e)(œ)sophaguses), c ...
and is digested in the stomach. The nasal cavity also houses the sense of smell and contributes greatly to taste sensation through its posterior communication with the mouth via the
choanae The choanae (: choana), posterior nasal apertures or internal nostrils are two openings found at the back of the nasal passage between the nasal cavity and the pharynx, in humans and other mammals (as well as crocodilians and most skinks). They ...
.


Clinical significance

Diseases of the nasal cavity include viral,
bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
l and
fungal A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as one of the tradit ...
infections, nasal cavity
tumors A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
, both benign and much more often malignant, as well as inflammations of the
nasal mucosa The nasal mucosa lines the nasal cavity. It is part of the respiratory mucosa, the mucous membrane lining the respiratory tract. The nasal mucosa is intimately adherent to the periosteum or perichondrium of the nasal conchae. It is continuous w ...
. Many problems can affect the nose, including: *
Deviated septum Nasal septum deviation is a physical disorder of the nose, involving a displacement of the nasal septum. Some displacement is common, affecting 80% of people, mostly without their knowledge. Signs and symptoms The nasal septum is the bone and ...
- a shifting of the wall that divides the nasal cavity into halves * Nasal polyps - soft growths that develop on the lining of the nose or sinuses *
Nosebleeds A nosebleed, also known as epistaxis, is an instance of bleeding from the nose. Blood can flow down into the stomach, and cause nausea and vomiting. In more severe cases, blood may come out of both nostrils. Rarely, bleeding may be so significan ...
*
Rhinitis Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. The inflammation is caused by viruses, bacteria, irritant ...
- inflammation of the nose and sinuses sometimes caused by
allergies Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include Allergic rhinitis, hay fever, Food allergy, food al ...
. The main symptom is a runny nose. *
Nasal fracture A nasal fracture, commonly referred to as a broken nose, is a fracture of one of the bones of the nose. Symptoms may include bleeding, swelling, bruising, and an inability to breathe through the nose. They may be complicated by other facial fra ...
s, also known as a broken nose *
Common cold The common cold, or the cold, is a virus, viral infectious disease of the upper respiratory tract that primarily affects the Respiratory epithelium, respiratory mucosa of the human nose, nose, throat, Paranasal sinuses, sinuses, and larynx. ...
* Sinonasal tumors


See also

*
Nasal irrigation Nasal irrigation (also called nasal lavage, nasal toilet, or nasal douche) is a personal hygiene practice in which the nasal cavity is washed to flush out mucus and debris from the nose and sinuses, in order to enhance nasal breathing. Nasal ir ...
*
Danger triangle of the face The danger triangle of the face consists of the area from the corners of the mouth to the bridge of the nose, including the nose and maxilla. Due to the special nature of the blood supply to the human nose and surrounding area, it is possib ...


References


External links

* * Gross anatomy dissection of the nasal cavity, vide

an

{{DEFAULTSORT:Nasal Cavity Nose Olfactory system Respiratory system Sensory organs Rhinology Otorhinolaryngology