Hydrophilization is a process used on hydrophobic drugs to increase their release rate from capsules, which depends on the rate of
dissolution, by covering the surfaces of their particles with minute droplets of a dissolved hydrophilic polymer (such as
methyl cellulose
Methyl cellulose (or methylcellulose) is a compound derived from cellulose. It is sold under a variety of trade names and is used as a thickener and emulsifier in various food and cosmetic products, and also as a bulk-forming laxative. Like cell ...
or
hydroxyethyl cellulose
Hydroxyethyl cellulose is a gelling and thickening agent derived from cellulose. It is widely used in cosmetics, cleaning solutions, and other household products.
Hydroxyethyl cellulose and methyl cellulose are frequently used with hydrophobic dr ...
).
In tablet or capsule formulations, this enhances the dissolution and disintegration of the drug.
[
]
References
{{Reflist
Dosage forms