Horror Fusionis
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ophthalmology Ophthalmology (, ) is the branch of medicine that deals with the diagnosis, treatment, and surgery of eye diseases and disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a ...
, horror fusionis is a condition in which the eyes have an unsteady deviation, with the extraocular muscles performing spasm-like movements that continuously shift the eyes away from the position in which they would be directed to the same point in space, giving rise to
diplopia Diplopia is the simultaneous perception of two images of a single object that may be displaced in relation to each other. Also called double vision, it is a loss of visual focus under regular conditions, and is often voluntary. However, when occ ...
. Even when the double vision images are made to nearly overlap using optical means such as
prism PRISM is a code name for a program under which the United States National Security Agency (NSA) collects internet communications from various U.S. internet companies. The program is also known by the SIGAD . PRISM collects stored internet ...
s, the irregular movements prevent binocular fusion. The name ''horror fusionis'' (Latin phrase literally meaning "fear of fusion") arises from the notion that the brain is, or at least appears to be, actively preventing binocular fusion. The condition is an extreme type of binocular fusion deficiency.


Symptoms

When the eye position is fully corrected (for example after surgical alignment of the eyes) or when the patient is provided with the best achievable prism correction, the patient does not experience binocular fusion and, instead, sees a double image that is very close to the fixation image and is perceived as "dancing around" it. The eyes display an unsteady misalignment.


Risk factors

''Horror fusionis'' is a rare condition and normally appears only in patients who have been treated by means of surgery or other interventions. Attempts to achieve stereoscopic vision, in particular anti-suppression therapy and other orthoptic exercises, may lead to double vision as undesired side effect, in particular also to ''horror fusionis''. In terms of outcome of strabismus surgery, monofixation syndrome is considered a better outcome than ''horror fusionis''.


Diagnosis

''Horror fusionis'' is diagnosed using a synoptophore: an image swept across the retina of the nonfixing eye at constant speed is perceived to change its speed in a specific way and then to "jump over" the fixation target. The specification of ''horror fusionis'' is usually distinguished from a more general condition called central fusion disruption syndrome, where the patient is unable to fuse or to suppress.


Management

Bielschowsky's original case was corrected by providing full optical correction to the underlying vision problem. Generally speaking, if the double vision is intractable by optical and other means and the patient needs relief from the disturbing double images, it may be indicated to use a more modest approach that simply ensures that the image of the weaker eye no longer interferes with the image of the dominant eye. This relieves the most disturbing symptoms, albeit at the cost of offering only subnormal binocular vision. Diplopia symptoms can be relieved by using
spectacles Glasses, also known as eyeglasses (American English), spectacles (Commonwealth English), or colloquially as specs, are Visual perception, vision eyewear with clear or tinted lens (optics), lenses mounted in a frame that holds them in front ...
that obscure or blur all or part of the view. This can be achieved for example by applying semi-opaque tape or clear
nail polish Nail polish (also known as nail varnish in British English or nail enamel) is a lacquer that can be applied to the human Nail (anatomy), fingernails or toenails to decorate and protect the nail plates. The formula has been revised repeatedly t ...
to a large central portion of one side of a pair of spectacles or to a part of both sides. Alternatively, an
opaque Opacity is the measure of impenetrability to electromagnetic or other kinds of radiation, especially visible light. In radiative transfer, it describes the absorption and scattering of radiation in a medium, such as a plasma, dielectric, shie ...
contact lens Contact lenses, or simply contacts, are thin lenses placed directly on the surface of the eyes. Contact lenses are ocular prosthetic devices used by over 150 million people worldwide, and they can be worn to correct vision or for cosmetic ...
that provides a fogging of the central area may offer better
cosmesis Cosmesis is the preservation, restoration, or bestowing of bodily beauty.'' Dorland's Medical Dictionary''. 25th ed. Philadelphia: W.B. Saunders Co.; 1995 In the medical context, it usually refers to the surgical correction of a disfiguring defect, ...
. Some patients can achieve
peripheral A peripheral device, or simply peripheral, is an auxiliary hardware device that a computer uses to transfer information externally. A peripheral is a hardware component that is accessible to and controlled by a computer but is not a core compo ...
fusion when it is merely a central area that is blended out in this manner. (See also binasal occlusion which obscures the nasal part of the field of view for both eyes.) A more drastic measure is the insertion of an opaque
intraocular lens An intraocular lens (IOL) is a lens (optics), lens implanted in the human eye, eye usually as part of a treatment for cataracts or for correcting other vision problems such as myopia, near-sightedness (myopia) and farsightedness, far-sightednes ...
to obscure the vision of one eye.


History

In 1935, ophthalmologist
Alfred Bielschowsky Alfred Bielschowsky (December 11, 1871 – April 5, 1940) was a German ophthalmologist. His specialty was physiology and pathology of the eye, particularly in regards to research of eye movement, space perception and diagnosis of oculomotor anomal ...
coined the term ''horror fusionis'' for this condition. In his case description, the condition was present years after surgical correction of strabismus acquired during childhood and co-existed with
aniseikonia Aniseikonia is an ocular condition where there is a significant difference in the perceived size of images. It can occur as an overall difference between the two eyes, or as a difference in a particular meridian. If the ocular image size in both ...
. Subsequently, spectacles for size correction ("iseikonic correction") allowed binocular fusion with depth perception to be achieved. Bielschowsky took note that the condition reappeared whenever the spectacles were not worn.
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References

{{Eye pathology Disorders of ocular muscles, binocular movement, accommodation and refraction Visual disturbances and blindness Vision