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Hexobendine is a
The reaction between 3,4,5-trimethoxybenzoyl chloride
CID:12350731
029-24-9(3). The last step involves the reaction between two molar equivalents of 3 with one molar equivalent of N,N’-dimethylethanediamine 10-70-3(4) completing the synthesis of hexobendine (5).
vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...
that acts as an adenosine reuptake inhibitor.
Synthesis
The reaction between 3,4,5-trimethoxybenzoyl chloride 521-61-3
5 (five) is a number, numeral and digit. It is the natural number, and cardinal number, following 4 and preceding 6, and is a prime number. It has attained significance throughout history in part because typical humans have five digits on eac ...
(1) and 3-chloropropanol 27-30-5(2) gives the corresponding ester, i.e. 3-chloropropyl 3,4,5-trimethoxybenzoateCID:12350731
029-24-9(3). The last step involves the reaction between two molar equivalents of 3 with one molar equivalent of N,N’-dimethylethanediamine 10-70-3(4) completing the synthesis of hexobendine (5).
See also
*Dilazep
Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.
It is used for the treatment of cardiopathy and renal disorders. Synthesis
The reaction of bis-(3-hydroxypropyl)-ethylene diamine (1) with 1-Bromo-3-chloropropane (2) give ...
References
Vasodilators Phenol ethers Benzoate esters Amines Adenosine reuptake inhibitors {{cardiovascular-drug-stub