Glutamatergic means "related to
glutamate
Glutamic acid (symbol Glu or E; known as glutamate in its anionic form) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a Essential amino acid, non-essential nutrient for humans, meaning that ...
". A glutamatergic agent (or drug) is a chemical that directly modulates the
excitatory amino acid (
glutamate
Glutamic acid (symbol Glu or E; known as glutamate in its anionic form) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a Essential amino acid, non-essential nutrient for humans, meaning that ...
/
aspartate
Aspartic acid (symbol Asp or D; the ionic form is known as aspartate), is an α-amino acid that is used in the biosynthesis of proteins. The L-isomer of aspartic acid is one of the 22 proteinogenic amino acids, i.e., the building blocks of protein ...
) system in the body or brain. Examples include
excitatory amino acid receptor agonist An excitatory amino acid receptor agonist, or glutamate receptor agonist, is a chemical substance which receptor agonist, agonizes one or more of the glutamate receptors.
Examples include:
* AMPA
* Glutamic acid
* Ibotenic acid
* Kainic acid
* N-M ...
s,
excitatory amino acid receptor antagonist An excitatory amino acid receptor antagonist, or glutamate receptor antagonist, is a chemical substance which antagonizes one or more of the glutamate receptors.
Examples include:
* AP5
* Barbiturates
* Dextromethorphan
* Dextrorphan
* Dizoci ...
s, and
excitatory amino acid reuptake inhibitor An excitatory amino acid reuptake inhibitor (EAARI) is a type of drug which inhibits the reuptake of the excitatory neurotransmitters glutamate and aspartate by blocking one or more of the excitatory amino acid transporters (EAATs).
Examples of ...
s.
See also
*
Adenosinergic
*
Adrenergic
Adrenergic means "working on adrenaline (epinephrine) or noradrenaline (norepinephrine)" (or on their receptors). When not further qualified, it is usually used in the sense of enhancing or mimicking the effects of epinephrine and norepinephrine ...
*
Cannabinoidergic
*
Cholinergic
*
Dopaminergic
Dopaminergic means "related to dopamine" (literally, "working on dopamine"), a common neurotransmitter. Dopaminergic substances or actions increase dopamine-related activity in the brain.
Dopaminergic pathways, Dopaminergic brain pathways facil ...
*
GABAergic
*
GHBergic
*
Glycinergic
*
Histaminergic
*
Melatonergic
*
Monoaminergic
*
Opioidergic
*
Serotonergic
*
Sigmaergic
References
Neurochemistry
Neurotransmitters
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