Foundation For Biomedical Research
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The Foundation for Biomedical Research (FBR) is an American nonprofit organization, 501(c)(3), located in Washington, DC. Established in 1981, the organization is dedicated to informing the news media, teachers, and other groups about the need for lab animals in medical and scientific research. The organization, together with its partner, the
National Association for Biomedical Research The National Association for Biomedical Research (NABR) is an American nonprofit organization, 501(c)(6), located in Washington, DC. NABR was formed in 1985 when the Association of Biomedical Research merged with the National Society for Medic ...
(NABR), argues that promoting animal research leads to improved health for both humans and animals. Its founding president is Frankie Trull.


Animal research

According to the U.S. Department of Agriculture (USDA), the total number of animals used in that country in 2005 was almost 1.2 million,2005 Report on Enforcement of the Animal Welfare Act
''U.S. Department of Agriculture'', Accessed 8 February 2008
excluding rats and mice. Some
animal rights Animal rights is the philosophy according to which many or all Animal consciousness, sentient animals have moral worth that is independent of their Utilitarianism, utility for humans, and that their most basic interests—such as avoiding s ...
supporters believe that
alternatives Founded in 1994, Alternatives, Action and Communication Network for International Development, is a non-governmental, international solidarity organization based in Montreal, Quebec, Canada. Alternatives works to promote justice and equality a ...
exist for animal models in research; however the vast majority of scientists believe there are no adequate alternatives which truly replace the roles which research animals play. In fact, recent research shows that 98% of the current drug pipeline relies on either dogs or non-human primates. According to the Foundation for Biomedical Research, animal research has been responsible for every medical breakthrough over the past century, although this position has been disputed by some animal rights activists and organizations. It cites animal research as leading to advances in antibiotics, blood transfusions, dialysis, organ transplantation, vaccinations, chemotherapy, bypass surgery, joint replacement, and methods for prevention, treatment, cure and control of disease, pain and suffering.


Nonhuman primates

Nonhuman primates have been at the forefront of animal research controversy over the last several years even though they represent less than one percent of all animals models used.The Critical Role of Nonhuman Primates in Research, https://fbresearch.org/wp-content/uploads/2016/08/NHP-White-Paper-Print-08-22-16.pdf. pg. 11. In August 2016, to counter criticism from animal rights' groups, a white paper coauthored by nine of the most premier scientific groups and titled
The Critical Role of Nonhuman Primates in Medical Research
' was released. Because of their incredible similarity to humans, primates such as rhesus macaques and chimpanzees, up until the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
ended public funding for chimpanzee research, have greatly contributed to many areas of medicine. Some specific advances, according to the white paper, are: the development of the MMR vaccine, the treatment of
leprosy Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damag ...
, HIV medication, a vaccine for
hepatitis B Hepatitis B is an infectious disease caused by the '' Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. ...
, and improvements in cancer treatment. One of the most recent advancements has been the development of a highly effective vaccine against the
Zika virus ''Zika virus'' (ZIKV; pronounced or ) is a member of the virus family ''Flaviviridae''. It is spread by daytime-active '' Aedes'' mosquitoes, such as '' A. aegypti'' and '' A. albopictus''. Its name comes from the Ziika Forest of Uganda, w ...
, which should soon be protecting both the people and primates that are most at risk of infection.


Dogs

Dogs have been used in research for decades and have been invaluable for treating many human and canine illnesses. Dogs contract many of the diseases humans do, from heart disease to cancer and they are also exposed to the same environment as humans. Canine research has led to many significant breakthroughs such as
hip replacement Hip replacement is a surgical procedure in which the hip joint is replaced by a prosthetic implant, that is, a hip prosthesis. Hip replacement surgery can be performed as a total replacement or a hemi (half) replacement. Such joint replacement o ...
s, development of cancer treatments, and research in stem cells,
diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ...
, and Alzheimer's disease.Dogs: The Essential Need for Animals in Medical Research, https://fbresearch.org/wp-content/uploads/2016/04/Dogs-In-Biomedical-Research-FBR.pdf Treatments for heartworms, parasites, and vaccinations against
parvovirus Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the p ...
,
rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, ...
, and
canine distemper Canine distemper virus (CDV) (sometimes termed footpad disease) is a viral disease that affects a wide variety of mammal families, including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felin ...
have also come from canine models.


Cats

Cats, like dogs, have also proven to be extremely helpful for developing treatments for both human and feline diseases. Cats have been a mainstay in research studies of neurological, cardiovascular, and respiratory diseases and the immune system. In particular, they have been valuable models for understanding the function of the
neuron A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. ...
, the chemical transmission of nerve impulses, and the functional organization of the brain. Neuroscientists studying cats have provided a map of the circuitry of the vertebral cortex revealing the major pathways that send signals from the eye to the brain. Cats have also been invaluable for the treatment of
leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ...
and both feline and human breast cancer. Feline leukemia used to be one of the most common killers of cats and about 85% died within three years of their diagnosis. However, with their help, scientists have developed a vaccine for feline leukemia and now more beloved pets get to spend more time with their families.


Rodents

In the U.S., the numbers of rats and mice used in animal research is estimated at 20 million a year, or 95% of the total number of lab animals. Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate. Mice also have genomes that are very similar to the human genome. This similarity allows researchers to recreate human diseases, such as breast cancer, in mice in order to understand how genes affect the development of disease. The Foundation advocates the highest quality of animal care and treatment, stating that the use of animals in research is a privilege, and that animals deserve our respect and the best possible care.


Activities

The Foundation for Biomedical Research conducts educational programs for the news media, teachers, students and parents, pet owners and other groups. FBR publishes a subscriber-based daily news service called Total E-clips featuring biomedical research news, medical breakthroughs, political and legislative and activism news. Since 1981, the FBR has monitored and analyzed the activities of animal rights organizations relating to researchers and institutions.


See also

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Animal testing Animal testing, also known as animal experimentation, animal research, and ''in vivo'' testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. This ...
*
History of animal testing The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. ...


References


External links


FBR websiteNABR websiteThe Lifesaving Benefits of Primate ResearchNHP White Paper
{{Authority control Animal testing Animal welfare organizations based in the United States