Excision BioTherapeutics is a
biopharmaceutical
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, t ...
company based in San Francisco focused on developing
gene therapies against HIV infection.
The company has a single,
CRISPR–Cas9 based therapy, EBT-101, under investigation. Initial investigation into the therapy was conducted by the lab of Kamel Khalili, a professor at
Temple University
Temple University (Temple or TU) is a public university, public Commonwealth System of Higher Education, state-related research university in Philadelphia, Philadelphia, Pennsylvania, United States. It was founded in 1884 by the Baptist ministe ...
. In July 2023 the US
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
granted EBT-101
fast-track status. In October 2023 an early-stage study on 3 people reported that the treatment appeared to be safe with no major side effects but no data on its effectiveness was disclosed.
See also
*
CRISPR gene editing#HIV/AIDS
References
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Pharmaceutical companies of the United States
Antiretroviral drugs
Gene therapy