Enoblituzumab is a monoclonal antibody designed for the treatment of cancer.
Statement On A Nonproprietary Name Adopted By The USAN Council - Enoblituzumab
''American Medical Association
The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
''. Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human B7-H3
Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the gene.
Structure
B7-H3 is a 316 amino acid-long type I transmembrane protein, existing in two isoforms determined by its extracellular domain. In ...
, a member of the B7 family of immune regulators.
This drug was developed by MacroGenics, Inc.
References
{{monoclonals for tumors
Monoclonal antibodies