Ehud Zohary
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Ehud Zohary (; born Nov 8, 1958) is an Israeli scientist,
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin ...
of
neurobiology Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, ...
at the Edmond and Lilly Safra Center for Brain Science and Alexander Silberman Institute of Life Sciences, the
Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; ) is an Israeli public university, public research university based in Jerusalem. Co-founded by Albert Einstein and Chaim Weizmann in July 1918, the public university officially opened on 1 April 1925. ...
.


Biography

Ehud Zohary was born and raised in
Israel Israel, officially the State of Israel, is a country in West Asia. It Borders of Israel, shares borders with Lebanon to the north, Syria to the north-east, Jordan to the east, Egypt to the south-west, and the Mediterranean Sea to the west. Isr ...
. He did his B.Sc. in
biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
at the Hebrew University of Jerusalem,  and continued studying towards his  Ph.D. degree in neurobiology at the Hebrew University under the supervision of Prof. Shaul Hochstein. In 1992, Zohary went to the United States for postdoctoral studies at
Stanford University Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth ...
, to join the research group of Bill Newsome, studying the neural correlates of
motion perception Motion perception is the process of inferring the speed and direction of elements in a scene based on visual, vestibular and proprioceptive inputs. Although this process appears straightforward to most observers, it has proven to be a difficul ...
. Zohary returned to Israel in 1994, and established a visual neuroscience research group at the department of Neurobiology, the Alexander Silberman Institute of Life Sciences,
the Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; ) is an Israeli public research university based in Jerusalem. Co-founded by Albert Einstein and Chaim Weizmann in July 1918, the public university officially opened on 1 April 1925. It is the second-ol ...
. In 2010 he was invited to join the newly established Edmond and Lilly Safra Center for Brain Science, and is current member of its faculty. He is founder of the Jerusalem Brain Community, and headed it from 2013 to 2020. Zohary was a visiting prof. at
Harvard university Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...
in 2004-2005 and a Hillgardt visiting Prof. at Stanford university in 2012–2013 Zohary is a faculty-member at the Alexander Silberman life-science institute, Hebrew University, following the footsteps of his grandfather,
Michael Zohary Michael Zohary (; born 9 April 1898 in Bóbrka, Galicia (Austria-Hungary); died 16 April 1983 in Jerusalem) was a pioneering Israeli botanist. Biography Michael Schein (later Zohary) was born into a Jewish family in Bóbrka, near Lviv (then Aus ...
, and father,
Daniel Zohary Daniel (Dani) Zohary (; 24 April 1926 - 16 December 2016) was an Israeli plant geneticist, agronomist, and professor at the Hebrew University. He was the co-author of a comprehensive review of the origin and spread of domesticated plants in southw ...
. He is married to Rachel Ben Eliyahu, a father of three daughters, and lives in
Jerusalem Jerusalem is a city in the Southern Levant, on a plateau in the Judaean Mountains between the Mediterranean Sea, Mediterranean and the Dead Sea. It is one of the List of oldest continuously inhabited cities, oldest cities in the world, and ...
.


Research

Ehud Zohary is studying
visual perception Visual perception is the ability to detect light and use it to form an image of the surrounding Biophysical environment, environment. Photodetection without image formation is classified as ''light sensing''. In most vertebrates, visual percept ...
and its development in normal and abnormal conditions. Some of his achievements are summarized below.


''The sensitivity of single neurons and motion perception''

Zohary's early research (at Stanford) was focused on understanding the ''neural basis'' of motion perception. Using simultaneous recordings from pairs of MT neurons, Zohary found that the firing rates of direction-selective neurons were typically mildly correlated on a trial-by-trial basis. Theoretical considerations showed that this "correlated noise" severely limits the benefits of pooling and may explain why the animal (who is presumably integrating information across wide populations of neurons) is not more sensitive to motion signals than the ''average'' neuron. These findings were later reviewed and highlighted.


''Visual associative memory and sequence memory''

After establishing his own lab at the Hebrew University Zohary and colleagues studied the neural basis of associative memory. Using single unit recordings, coupled with neural network modelling techniques, they tested and verified key predictions that stem from ''attractor network theory.'' As expected from the theory, monkeys naturally categorized visual images according to their ordinal number''.''


''Reorganization of the visual cortex following blindness''  

The loss of vision does ''not'' render the
visual cortex The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalam ...
completely useless. Instead, regions in the occipital cortex of people blinded at early age are activated when they read
Braille Braille ( , ) is a Tactile alphabet, tactile writing system used by blindness, blind or visually impaired people. It can be read either on embossed paper or by using refreshable braille displays that connect to computers and smartphone device ...
. Yet Braille, being a ''reading process,'' involves more than just fine tactile judgments. Indeed, Zohary and colleagues found using
fMRI Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...
that in the congenitally blind, regions in the occipital lobe are activated during language processes (retrieval of words from memory, in the absence of any sensory input) and their activation level is correlated with memory capabilities. They further showed that blind have superior serial memory performance. Moreover, targeted disruption of the normal activity in the “visual” cortex during verb generation lead to errors in task performance in the congenitally blind but not in the sighted.  Thus, long term blindness from birth, dramatically alters the functional architecture of the human brain, in seemingly beneficial ways for the blind person. These initial findings were replicated and extended later and reviewed thoroughly. ''The possibilities and limits for visual function recovery after prolonged blindness from birth'' Zohary's latest research is focused on the development of vision functions following prolonged visual deprivation since birth. Zohary's Project Eye Opener, is centered around children in
Ethiopia Ethiopia, officially the Federal Democratic Republic of Ethiopia, is a landlocked country located in the Horn of Africa region of East Africa. It shares borders with Eritrea to the north, Djibouti to the northeast, Somalia to the east, Ken ...
that have been blind from birth for years due to untreated
cataract A cataract is a cloudy area in the lens (anatomy), lens of the eye that leads to a visual impairment, decrease in vision of the eye. Cataracts often develop slowly and can affect one or both eyes. Symptoms may include faded colours, blurry or ...
. Project eyeopener enables a rare assessment of vision restoration after the “critical period" for visual development. Contrary to this dogma, the utility of surgery at relatively late age for vision restoration is obvious. Still, there are some limits to the capabilities that can be attained.


Awards and honors

*1995: Alon Scholarship (given to the top 20 Israeli tenure track new lecturers in all fields and universities). SPONSOR: Council for Higher Education, Israel. *1998: Ben Porat presidential award, for the most prominent young investigator (under 40) in all fields at the Hebrew University of Jerusalem *1999: Golda Meir award for tenure track fellows. SPONSOR: Golda Meir Foundation *2004: 21st century science initiative award: Bridging Brain, Mind and Behavior SPONSOR: The McDonnel Foundation *2012-13: Hilgard award for visiting professor at Stanford University


References


External links

* * {{DEFAULTSORT:Zohary, Ehud Living people 1958 births Israeli neuroscientists