David Ernest James (born in Sydney in 1958) is a
cell biologist who discovered the glucose transporter
GLUT4
Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the ''SLC2A4'' gene. GLUT4 is the insulin-regulated glucose transporter found primarily in a ...
. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation to the cell surface, the topological mapping of the insulin signal transduction pathway, the creation of a method for studying ''in vivo'' metabolism in small animals, and the use of this method to gain insights into whole-animal fuel metabolism and homeostasis.
In 1979 he graduated with a BSc (Hons) from the
University of New South Wales
The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensiv ...
, and gained his
Ph.D. at the
Garvan Institute of Medical Research in 1985.
Subsequently he pursued
postdoc
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pu ...
research at
Boston University
Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original cam ...
and
Washington University in St. Louis in the
USA. In 1993 he returned to Australia, first to Brisbane and then once again at the Garvan Institute. In 2014 he moved to the
University of Sydney
The University of Sydney (USYD), also known as Sydney University, or informally Sydney Uni, is a public research university located in Sydney, Australia. Founded in 1850, it is the oldest university in Australia and is one of the country's si ...
.
He currently holds joint appointments as the Leonard P Ullmann Chair in Molecular Systems Biology and as the Domain Leader for Biology at the Charles Perkins Centre at The University of Sydney.
Awards and honours
* 1993–1997:
Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of Glaxo ...
Research Fellowship
* 1999: Glaxo Wellcome Australia Medal
* 2000: Mary Kugel Award for services to the Juvenile Diabetes Foundation
* 2006: Kellion Award from the Australian Diabetes Society
* 2007: Fellow of the
Australian Academy of Science
The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Soc ...
* 2008: Millennium Award, Diabetes Australian Research Trust
* 2014: ANZCDBS President’s Medal
* 2016: NSW Premier’s Prize for Medical Research
* 2020:
Australian Laureate Fellowship
The Australian Laureate Fellowship is an Australian professorial research fellowship awarded by the Australian Research Council. Up to 17 fellows are chosen each year for five-year awards.
Kathleen Fitzpatrick and Georgina Sweet fellowships
In 20 ...
See also
*
GLUT 4
*
Charles Perkins Centre
*
University of Sydney
The University of Sydney (USYD), also known as Sydney University, or informally Sydney Uni, is a public research university located in Sydney, Australia. Founded in 1850, it is the oldest university in Australia and is one of the country's si ...
References
External links
Professor David James, University of SydneyMetabolic Cybernetics LabCharles Perkins Centre
Australian biologists
Living people
1958 births
Fellows of the Australian Academy of Science
University of Sydney faculty
Garvan Institute of Medical Research alumni
University of New South Wales alumni
University of New South Wales faculty
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