Dicentrine is an
aporphinic alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
found in several plant species, mainly from family
Lauraceae
Lauraceae, or the laurels, is a plant Family (biology), family that includes the bay laurel, true laurel and its closest relatives. This family comprises about 2850 known species in about 45 genus (biology), genera worldwide. They are dicotyled ...
, including ''
Lindera megaphylla''.
At high doses, dicentrine shows
antinociceptive activity in a
mouse model of pain.
It probably acts via a
TRPA1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Mustard and Wasabi Receptor, is a protein that in humans is encoded by the ''TRPA1'' (and in mice and rats by ...
-dependent mechanism.
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]
References
Aporphine alkaloids
Lindera
{{alkaloid-stub